Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Travis E. Monnell"'
Autor:
Ravindra Kumar, Jasbir Seehra, Kathryn W. Underwood, R. Scott Pearsall, Jeffrey A. Ucran, Nicolas Solban, Travis E. Monnell, Roselyne Castonguay, Asya V. Grinberg, Aaron W. Mulivor, Eileen G. Pobre, Dianne Mitchell
Activin receptor–like kinase-1 (ALK1) is a type I, endothelial cell–specific member of the transforming growth factor-β superfamily of receptors known to play an essential role in modulating angiogenesis and vessel maintenance. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d62b66268345b52b0f0b8aa7db8311c
https://doi.org/10.1158/1535-7163.c.6532256
https://doi.org/10.1158/1535-7163.c.6532256
Autor:
Ravindra Kumar, Jasbir Seehra, Kathryn W. Underwood, R. Scott Pearsall, Jeffrey A. Ucran, Nicolas Solban, Travis E. Monnell, Roselyne Castonguay, Asya V. Grinberg, Aaron W. Mulivor, Eileen G. Pobre, Dianne Mitchell
Supplementary Table 1 from ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5eebbcf9ce0bdb38c2a3af3223ee68
https://doi.org/10.1158/1535-7163.22486142
https://doi.org/10.1158/1535-7163.22486142
Autor:
Jennifer Lachey, Kathryn W. Underwood, Matthew S. Spaits, Samuel M. Cadena, Kathleen N. Tomkinson, Ravindra Kumar, Travis E. Monnell, R. Scott Pearsall
Publikováno v:
Journal of Applied Physiology. 109:635-642
This is the first report that inhibition of negative regulators of skeletal muscle by a soluble form of activin type IIB receptor (ACE-031) increases muscle mass independent of fiber-type expression. This finding is distinct from the effects of selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531e1fd51c10a4aa9c6349a66ddb2f22
https://doi.org/10.1152/japplphysiol.00866.2009
https://doi.org/10.1152/japplphysiol.00866.2009
Autor:
Ravindra Kumar, Roselyne Castonguay, Travis E. Monnell, Jasbir Seehra, Kathryn W. Underwood, Dianne C. Mitchell, Aaron W. Mulivor, Eileen Pobre, R. Scott Pearsall, Nicolas Solban, Jeffrey A. Ucran, Asya Grinberg
Publikováno v:
Molecular Cancer Therapeutics. 9:379-388
Activin receptor–like kinase-1 (ALK1) is a type I, endothelial cell–specific member of the transforming growth factor-β superfamily of receptors known to play an essential role in modulating angiogenesis and vessel maintenance. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6d29c967b30e7e630139bda1ff6884
https://doi.org/10.1158/1535-7163.mct-09-0650
https://doi.org/10.1158/1535-7163.mct-09-0650
Autor:
Benjamin J. Roberts, Jeffrey A. Ucran, Mary L. Bouxsein, Jasbir Seehra, Amelia E. Pearsall, Monique V. Davies, Deepali Khanzode, Tod Marvell, R. Scott Pearsall, Kathryn W. Underwood, Ravindra Kumar, Travis E. Monnell, Roberto J. Fajardo, Rajaram K. Manoharan
Publikováno v:
Bone. 46:64-71
A recent study suggests that activin inhibits bone matrix mineralization, whereas treatment of mice with a soluble form of the activin type IIA receptor markedly increases bone mass and strength. To further extend these observations, we determined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6ebca4442ed11b941fc52adfa07cea
https://doi.org/10.1016/j.bone.2009.09.018
https://doi.org/10.1016/j.bone.2009.09.018
Autor:
Jasbir Seehra, Ben Umiker, Joseph Barberio, Kathryn W. Underwood, Jeffrey A. Ucran, Alan Koncarevic, June Liu, Katia Liharska, Matthew S. Spaits, Jennifer Lachey, Monique V. Davies, Scott Pearsall, Kathleen N. Tomkinson, Ravindra Kumar, Theresa Baker, Abigail Pullen, Travis E. Monnell, Elizabeth Howard, Sako Dianne S, Milton Cornwall-Brady, Asya Grinberg
Publikováno v:
Endocrinology. 151(9)
Androgen deprivation, a consequence of hypogonadism, certain cancer treatments, or normal aging in men, leads to loss of muscle mass, increased adiposity, and osteoporosis. In the present study, using a soluble chimeric form of activin receptor type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f08f742b552fecca4ccc8de8af2a1c1
https://pubmed.ncbi.nlm.nih.gov/20573726
https://pubmed.ncbi.nlm.nih.gov/20573726
Autor:
June Liu, Kathleen N. Tomkinson, Ravindra Kumar, Asya Grinberg, Travis E. Monnell, Eileen Pobre, Kathryn W. Underwood, R. Scott Pearsall, Monique V. Davies, Roselyne Castonguay, Jasbir Seehra, Sako Dianne S, Amy Andreucci, Jeffrey A. Ucran, Erik Martinez-Hackert, Silas Maniatis
The single transmembrane domain serine/threonine kinase activin receptor type IIB (ActRIIB) has been proposed to bind key regulators of skeletal muscle mass development, including the ligands GDF-8 (myostatin) and GDF-11 (BMP-11). Here we provide a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48dd8716b34614994e3d23060decabc
https://europepmc.org/articles/PMC2898293/
https://europepmc.org/articles/PMC2898293/
Autor:
Kathryn W. Underwood, Tod Marvell, Monique V. Davies, Jasbir Seehra, Ravindra Kumar, Jeffrey A. Ucran, Travis E. Monnell, Mary L. Bouxsein, Sutada Lotinun, Roland Baron, R. Scott Pearsall, Roberto J. Fajardo
Publikováno v:
Bone. 46(4)
Activin A belongs to the TGF-beta superfamily and plays an important role in bone metabolism. It was reported that a soluble form of extracellular domain of the activin receptor type IIA (ActRIIA) fused to the Fc domain of murine IgG, an activin anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eaeb7166924b617d5cd0dfa01dccdbd
https://pubmed.ncbi.nlm.nih.gov/20080223
https://pubmed.ncbi.nlm.nih.gov/20080223
Autor:
Benjamin Umiker, Milton Cornwall-Brady, Y. Kawamoto, June Liu, Sako Dianne S, Jasbir Seehra, Ravi Kumar, Kathryn W. Underwood, Shana Walrond, Nicolas Solban, Rita Steeves, R. Scott Pearsall, Kathleen N. Tomkinson, Travis E. Monnell
Publikováno v:
Bone. 46:S32-S33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4475b2730b77482eafadb1ac21b5c8be
https://doi.org/10.1016/j.bone.2010.01.067
https://doi.org/10.1016/j.bone.2010.01.067
Autor:
Kathryn W. Underwood, Sako Dianne S, Ravindra Kumar, Katia Liharska, Travis E. Monnell, Jeff Ucran, Samuel M. Cadena, Dianne C. Mitchell, R. Scott Pearsall, Rajasekhar N.V.S. Suragani
Publikováno v:
Blood. 116:4230-4230
Abstract 4230 We have previously shown that administration of ACE-536, a soluble form of a modified activin type IIB receptor, is an effective therapy in both acute and chronic animal models of anemia. We have further demonstrated that ACE-536 induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2f5b1f1a761a6f725750a7a8e7b9d2c
https://doi.org/10.1182/blood.v116.21.4230.4230
https://doi.org/10.1182/blood.v116.21.4230.4230