Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Travis E. Hartman"'
Autor:
Ritu Sharma, Travis E. Hartman, Tiago Beites, Jee-Hyun Kim, Hyungjin Eoh, Curtis A. Engelhart, Linnan Zhu, Daniel J. Wilson, Courtney C. Aldrich, Sabine Ehrt, Kyu Young Rhee, Dirk Schnappinger
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Nicotinamide adenine dinucleotide (NAD) and its phosphorylated derivative (NADP) are essential cofactors that participate in hundreds of biochemical reactions and have emerged as therapeutic targets in cancer, metabolic disorders, neurodegen
Externí odkaz:
https://doaj.org/article/58351c1678134138a2c61182375d718c
Autor:
Kaj M. Kreutzfeldt, Robert S. Jansen, Travis E. Hartman, Alexandre Gouzy, Ruojun Wang, Inna V. Krieger, Matthew D. Zimmerman, Martin Gengenbacher, Jansy P. Sarathy, Min Xie, Véronique Dartois, James C. Sacchettini, Kyu Y. Rhee, Dirk Schnappinger, Sabine Ehrt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Drug tolerance complicates the treatment of tuberculosis. Here, Kreutzfeldt et al. show that the protein CinA mediates drug tolerance in Mycobacterium tuberculosis by cleaving NAD-drug adducts, suggesting CinA as a potential target to shorten tubercu
Externí odkaz:
https://doaj.org/article/0ffbbce15de04ec482009cd19552b697
Autor:
Shilpika Pandey, Amrita Singh, Guangli Yang, Felipe B. d’Andrea, Xiuju Jiang, Travis E. Hartman, John W. Mosior, Ronnie Bourland, Ben Gold, Julia Roberts, Annie Geiger, Su Tang, Kyu Rhee, Ouathek Ouerfelli, James C. Sacchettini, Carl F. Nathan, Kristin Burns-Huang
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Phosphopantetheinyl hydrolase, PptH (Rv2795c), is a recently discovered enzyme from Mycobacterium tuberculosis that removes 4′-phosphopantetheine (Ppt) from holo-carrier proteins (CPs) and thereby opposes the action of phosphopantetheinyl
Externí odkaz:
https://doaj.org/article/87cd1111aab44680835d04e045364dcd
Autor:
JoAnn M. Tufariello, Christopher A. Kerantzas, Catherine Vilchèze, R. Brent Calder, Eric K. Nordberg, Jack A. Fischer, Travis E. Hartman, Eva Yang, Timothy Driscoll, Laura E. Cole, Robert Sebra, Shahina B. Maqbool, Alice R. Wattam, William R. Jacobs
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Mycobacterium haemophilum is an emerging pathogen associated with a variety of clinical syndromes, most commonly skin infections in immunocompromised individuals. M. haemophilum exhibits a unique requirement for iron supplementation to suppo
Externí odkaz:
https://doaj.org/article/90a51ee400054f14b7349d432b7286d1
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT The new medicinal compound bedaquiline (BDQ) kills Mycobacterium tuberculosis by inhibiting F1Fo-ATP synthase. BDQ is bacteriostatic for 4 to 7 days and kills relatively slowly compared to other frontline tuberculosis (TB) drugs. Here we sho
Externí odkaz:
https://doaj.org/article/69aa159f87974e569df926655462ea6a
Autor:
Vijay Soni, Travis E. Hartman
This book Introduces the extensive applications of metabolomics from all possible areas of research and development so that not only an undergraduate can understand the advancement of metabolomics, but an entrepreneur can harness the knowledge to add