Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Travis E. Faust"'
Autor:
Travis E. Faust, Philip A. Feinberg, Ciara O’Connor, Riki Kawaguchi, Andrew Chan, Hayley Strasburger, Maximilian Frosch, Margaret A. Boyle, Takahiro Masuda, Lukas Amann, Klaus-Peter Knobeloch, Marco Prinz, Anne Schaefer, Dorothy P. Schafer
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113031- (2023)
Summary: Cre/loxP technology has revolutionized genetic studies and allowed for spatial and temporal control of gene expression in specific cell types. Microglial biology has particularly benefited because microglia historically have been difficult t
Externí odkaz:
https://doaj.org/article/8f955c3906d442979396cdb0bef5da10
Autor:
Charlotte R. Wayne, Luca Bremner, Travis E. Faust, Violeta Durán-Laforet, Nicole Ampatey, Sarah J. Ho, Philip A. Feinberg, Panos Arvanitis, Bogoljub Ciric, Chunsheng Ruan, Wassim Elyaman, Shannon L. Delaney, Wendy S. Vargas, Susan Swedo, Vilas Menon, Dorothy P. Schafer, Tyler Cutforth, Dritan Agalliu
Publikováno v:
bioRxiv
SUMMARYGroup AStreptococcus(GAS) infections can cause neuropsychiatric sequelae in children due to post-infectious encephalitis. Multiple GAS infections induce migration of Th17 lymphocytes from the nose into the brain, which are critical for microgl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b5fcccbd67454e32dcaac804d21a3e
https://europepmc.org/articles/PMC10197575/
https://europepmc.org/articles/PMC10197575/
Autor:
Sol Beccari, Virginia Sierra-Torre, Jorge Valero, Marta Pereira-Iglesias, Mikel García-Zaballa, Federico N. Soria, Laura De Las Heras-Garcia, Alejandro Carretero-Guillen, Estibaliz Capetillo-Zarate, Maria Domercq, Paloma R. Huguet, David Ramonet, Ahmed Osman, Wei Han, Cecilia Dominguez, Travis E. Faust, Omar Touzani, Olatz Pampliega, Patricia Boya, Dorothy Schafer, Guillermo Mariño, Emmanuelle Canet-Soulas, Klas Blomgren, Ainhoa Plaza-Zabala, Amanda Sierra
Publikováno v:
Scopus
31 p.-12 fig.-1 tab. We dedicate this paper to Takashi Umekawa, who generated the HI model at the Karolinska Institute, and unfortunately passed away in 2018.
Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neuron
Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014b66a4df545c9971c93aa98a94ab37
Autor:
Philip A. Feinberg, Shannon C. Becker, Leeyup Chung, Loris Ferrari, David Stellwagen, Christelle Anaclet, Violeta Durán-Laforet, Travis E. Faust, Rachita K. Sumbria, Dorothy P. Schafer
Publikováno v:
J Neurosci
Interferon regulatory factor 8 (IRF8) is a transcription factor necessary for the maturation of microglia, as well as other peripheral immune cells. It also regulates the transition of microglia and other immune cells to a pro-inflammatory phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5026e33398d9e72dde9db2ded2fbaa0
https://europepmc.org/articles/PMC9374154/
https://europepmc.org/articles/PMC9374154/
Autor:
I-Hao Wang, Evan Murray, Greg Andrews, Hao-Ching Jiang, Sung Jin Park, Elisa Donnard, Violeta Durán-Laforet, Daniel M. Bear, Travis E. Faust, Manuel Garber, Christina E. Baer, Dorothy P. Schafer, Zhiping Weng, Fei Chen, Evan Z. Macosko, Paul L. Greer
Publikováno v:
Nat Neurosci
The olfactory system’s ability to detect and discriminate between the vast array of chemicals present in the environment is critical for an animal’s survival. In mammals, the first step of this odor processing is executed by olfactory sensory neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e372fecd09e95875510bb7d6168bae1
https://europepmc.org/articles/PMC9281876/
https://europepmc.org/articles/PMC9281876/
Autor:
Jorge Valero, Ahmed M. Osman, Alejandro Carretero-Guillén, Guillermo Mariño, Amanda Sierra, Wei Han, Mikel Garcia-Zaballa, David Ramonet, Dorothy P. Schafer, Omar Touzani, Travis E Faust, Patricia Boya, Estibaliz Capetillo-Zarate, Virginia Sierra-Torre, Emmanuelle Canet-Soulas, Ainhoa Plaza-Zabala, Paloma Huguet, María Domercq, Sol Beccari, Klas Blomgren, Cecilia A. Dominguez
Microglial phagocytosis is rapidly emerging as a therapeutic target in neurodegenerative and neurological disorders. An efficient removal of cellular debris is necessary to prevent buildup damage of neighbor neurons and the development of an inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007996eefa8fa4774f8410200781ea41
https://doi.org/10.1101/2021.11.12.468358
https://doi.org/10.1101/2021.11.12.468358
Autor:
Travis E Faust, Dorothy P. Schafer
Publikováno v:
Immunity
Summary Early prenatal inflammatory conditions are thought to be a risk factor for different neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy causes abnormal behavior in offspring, but whether these defects resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129dda4b0ebdfe8306f56c4e68b953cb
https://pubmed.ncbi.nlm.nih.gov/34758338
https://pubmed.ncbi.nlm.nih.gov/34758338
Publikováno v:
Nat Rev Neurosci
Nearly 60 years have passed since the initial discovery by Hubel and Wiesel that changes in neuronal activity can elicit developmental rewiring of the central nervous system (CNS). Over this time, we have gained a more comprehensive picture of how bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed909307a6b9cbcda582d07b43b304c
https://pubmed.ncbi.nlm.nih.gov/34545240
https://pubmed.ncbi.nlm.nih.gov/34545240
Autor:
Daniel Wood, Brian K. Lee, Travis E. Faust, Hanna Jaaro-Peled, Tyler Cash-Padgett, Trexy Palen, Sneha Saha, Dwight E. Bergles, Jed W. Fahey, Amit Agarwal, Antonello Bonci, Wendy Xin, Akira Sawa
Mutations in the astrocyte-enriched enzyme aldehyde dehydrogenase 7a1 (ALDH7A1) cause a neonatal epilepsy accompanied by treatment-resistant, inter-ictal neuropsychiatric symptoms. Nevertheless, the mechanistic impact of ALDH7A1 dysfunction in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bc8b5ce10e21075b01b6d4cdf1c591
Mitochondria play a crucial role in neuronal function, especially in energy production, generation of reactive oxygen species, and calcium signaling. Multiple lines of evidence have suggested possible involvement of mitochondrial deficits in major ps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e486fca4cd12bf07c00f4e1a90220fac
https://europepmc.org/articles/PMC6469392/
https://europepmc.org/articles/PMC6469392/