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pro vyhledávání: '"Travis Anthoine"'
Autor:
Guilong Charles Cheng, Neil F. Langille, Alicia Zeng, Jenil Patel, Chris Scardino, Travis Anthoine, William E. Lake, Scott W. Roberts, Matthew G. Beaver, John L. Tucker, Shawn D. Walker, Dawn E. Cohen, William Powazinik, Peter K. Dornan, Sheng Cui, Simone Spada, Susan P. Lucas
Publikováno v:
Organic Process Research & Development. 24:481-489
Epoxyketone 4 is an isolated intermediate in the manufacturing route to the commercial proteasome inhibitor carfilzomib (Kyprolis). Commercial process development and optimization efforts toward th...