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pro vyhledávání: '"Traunbauer A"'
Akademický článek
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Autor:
Simon J. Hogg, Stephin J. Vervoort, Sumit Deswal, Christopher J. Ott, Jason Li, Leonie A. Cluse, Paul A. Beavis, Phillip K. Darcy, Benjamin P. Martin, Andrew Spencer, Anna K. Traunbauer, Irina Sadovnik, Karin Bauer, Peter Valent, James E. Bradner, Johannes Zuber, Jake Shortt, Ricky W. Johnstone
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2162-2174 (2017)
Summary: BET inhibitors (BETi) target bromodomain-containing proteins and are currently being evaluated as anti-cancer agents. We find that maximal therapeutic effects of BETi in a Myc-driven B cell lymphoma model required an intact host immune syste
Externí odkaz:
https://doaj.org/article/7831449cccec4074b10637bac98536e0
Autor:
Charles H. Adelmann, Anna K. Traunbauer, Kendall J. Condon, Brandon Chen, Tenzin Kunchok, David M. Sabatini, Caroline A. Lewis, Sze Ham Chan
Publikováno v:
Nature
Dozens of genes contribute to the vast variation in human pigmentation. Many of these encode proteins that localize to the melanosome, the lysosome-related organelle that synthesizes pigment, but have unclear functions 1,2. Here, we describe the Mela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7671fc6e457f6443954f58bd653bac0a
http://europepmc.org/articles/PMC7770032
http://europepmc.org/articles/PMC7770032
Autor:
Matthias Hinterndorfer, Max Gijsbertsen, Gintautas Vainorius, Johannes Zuber, Ulrich Elling, Thomas R Burkard, Tobias Neumann, Julian Jude, Maria Hubmann, Michaela Fellner, Alexander Schleiffer, Anna K. Traunbauer, Melanie Talata De Almeida, Georg Michlits
Publikováno v:
Nature Methods. 17:708-716
CRISPR-Cas9 screens have emerged as a transformative approach to systematically probe gene functions. The quality and success of these screens depends on the frequencies of loss-of-function alleles, particularly in negative-selection screens widely a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5796a0c8ff28b9823408cfd369ddbea7
https://doi.org/10.1038/s41592-020-0850-8
https://doi.org/10.1038/s41592-020-0850-8
Autor:
Ratna Tripathy, Andrew Edwards, Marco Repic, Anna Přistoupilová, Ivo Gut, Elliott H. Sherr, David J. Adams, Ines Leca, Tomas Honzik, Lukas Landler, Viktor Stránecký, Thomas Gstrein, Martin W. Breuss, Anna K. Traunbauer, Stanislav Kmoch, Marta Gut, Thomas M. Keane, Gavril Rosoklija, Karl Mechtler, David A. Keays, Sergi Beltran, Gerhard Dürnberger, Tobias Hochstoeger, Sandra Pilat-Carotta, Andi H. Hansen, Johannes Zuber, Jonathan Flint
Publikováno v:
Nature Neuroscience. 21:207-217
The formation of the vertebrate brain requires the generation, migration, differentiation and survival of neurons. Genetic mutations that perturb these critical cellular events can result in malformations of the telencephalon, providing a molecular w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fa41583ea8593ac16f72e814ec4969
https://doi.org/10.1038/s41593-017-0053-5
https://doi.org/10.1038/s41593-017-0053-5
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Christopher J. Ott, Sumit Deswal, Jason Li, Karin Bauer, Stephin J. Vervoort, Leonie A. Cluse, Anna K. Traunbauer, Ricky W. Johnstone, Irina Sadovnik, Johannes Zuber, Simon J. Hogg, James E. Bradner, Jake Shortt, Peter Valent, Paul A. Beavis, Phillip K. Darcy, Andrew Spencer, Benjamin P. Martin
Publikováno v:
Cell Reports
Cell Reports, Vol 18, Iss 9, Pp 2162-2174 (2017)
Cell Reports, Vol 18, Iss 9, Pp 2162-2174 (2017)
Summary BET inhibitors (BETi) target bromodomain-containing proteins and are currently being evaluated as anti-cancer agents. We find that maximal therapeutic effects of BETi in a Myc-driven B cell lymphoma model required an intact host immune system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa91098d46cd68f2f627d68e32d2977
Autor:
Daniel Gerlach, Sabine Olt, Stefanie Schlager, Sophia M Blake, Anja Ebert, Manfred Koegl, Oliver Bergner, Johannes Wachter, Anna K. Traunbauer, Mark Pearson, Norbert Kraut, Johannes Zuber, Christoph Albrecht, Barbara Drobits, Norbert Schweifer, Martina Minnich, Vittoria Zinzalla, Francesca Trapani, Matthias Hinterndorfer, Tilman Voss, Julian Jude, Darryl B. McConnell, Carina Salomon
Publikováno v:
Oncotarget
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphomas worldwide and is characterized by a high diversity of genetic and molecular alterations. Chromosomal translocations and mutations leading to deregulated expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e39bab60623b240ea21f21b00de8086
https://pubmed.ncbi.nlm.nih.gov/32180900
https://pubmed.ncbi.nlm.nih.gov/32180900
Autor:
Georg, Michlits, Julian, Jude, Matthias, Hinterndorfer, Melanie, de Almeida, Gintautas, Vainorius, Maria, Hubmann, Tobias, Neumann, Alexander, Schleiffer, Thomas Rainer, Burkard, Michaela, Fellner, Max, Gijsbertsen, Anna, Traunbauer, Johannes, Zuber, Ulrich, Elling
Publikováno v:
Nature methods. 17(7)
CRISPR-Cas9 screens have emerged as a transformative approach to systematically probe gene functions. The quality and success of these screens depends on the frequencies of loss-of-function alleles, particularly in negative-selection screens widely a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efe55b45f3c06d0c5e22dc18429d8dfe
https://pubmed.ncbi.nlm.nih.gov/32514112
https://pubmed.ncbi.nlm.nih.gov/32514112