Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Traudl Henn"'
Autor:
Stig Bojesen, Dirk Scharr, Uta Fuchs, Rainer M. Bohle, Petra Korth, Arndt Borkhardt, Traudl Henn, Oskar A. Haas, Susanne Viehmann, Jochen Harbott, Reinald Repp, Ulrich Jaeger, Dominique Bartelheimer, Fritz Lampert, Ivan F. Loncarevic
Publikováno v:
Proceedings of the National Academy of Sciences. 97:9168-9173
We have isolated the human GRAF gene (for GTPase regulator associated with the focal adhesion kinase pp125 FAK ). This gene was fused with MLL in a unique t(5;11)(q31;q23) that occurred in an infant with juvenile myelomonocytic leukemia. GRAF encodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c99933b54e96778636aaa6fa2128b9
https://doi.org/10.1073/pnas.150079597
https://doi.org/10.1073/pnas.150079597
Autor:
Gerhard Fritsch, Dieter Printz, Frank Stolz, Susanna Fischer, Oskar A. Haas, Helmut Gadner, Michael Dworzak, Traudl Henn, E. Renate Panzer-Grümayer, Gertraud Fröschl, Christine Fleischer
Publikováno v:
Experimental Hematology. 27:673-681
We recently investigated samples of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) and normal bone marrow (BM). We found that leukemic blasts, compared to their physiologic counterpart cells, frequently display aberrant phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51f96d5b1460915575e516aa4208d40d
https://doi.org/10.1016/s0301-472x(98)00071-x
https://doi.org/10.1016/s0301-472x(98)00071-x
Autor:
Marion Kos, Florian Überall, Alexander Egle, Andreas Villunger, Traudl Henn, Inge Tinhofer, Richard Greil, Karl Maly, Daniel Egle
Publikováno v:
British Journal of Haematology. 102:1069-1080
It has been shown that granulocyte/macrophage colony stimulating factor (GM-CSF) is able to support myeloma cell propagation in cooperation with interleukin (IL)-6, the major growth factor for malignant plasma cells, although the biological mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f91a0f5d25e4821f4affa250655314
https://doi.org/10.1046/j.1365-2141.1998.00880.x
https://doi.org/10.1046/j.1365-2141.1998.00880.x
Autor:
Jutta Hammermann, Oskar A. Haas, Thomas Leis, Jochen Harbott, R. Repp, Arndt Borkhardt, Traudl Henn, Fritz Lampert, Joachim Kreuder
Publikováno v:
Oncogene. 14:195-202
We report the cloning and characterization of the entire AFX gene which fuses to MLL in acute leukemias with a t(X;11)(q13;q23). AFX consists of two exons and encodes for a protein of 501 amino acids. We found that normal B- and T-cells contain simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87c276d7d6be916c3a3391d812007b4
https://doi.org/10.1038/sj.onc.1200814
https://doi.org/10.1038/sj.onc.1200814
Autor:
Christoph M. Barnas, Christoph Brunner, Elke Kleiner, Christoph Lengauer, Wilfried Ellmeier, Paula Stapleton, Traudl Henn, Andreas Weith, Patrick Onyango
Publikováno v:
Genomics. 29:607-615
In an approach to mapping physically the most distal 30 Mb of human chromosome 1p, region-specific clone libraries were generated by microdissection and microcloning. PFGE blot hybridization of single or low-copy microclones against rare-cutter diges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4e91503a1c4450d9e46320fdd5aca5
https://doi.org/10.1006/geno.1995.9006
https://doi.org/10.1006/geno.1995.9006
Autor:
Klaus Geissler, Theresia Maier-Dobersberger, Gerlinde Mitterbauer, Oskar A. Haas, A Gaiger, E Hörth, Christine Mannhalter, Hildegard Greinix, Klaus Lechner, Thomas Lion, Traudl Henn
Publikováno v:
Blood. 86:2371-2378
The translocation t(9;22) in chronic myeloid leukemia (CML) generates a bcr-abl fusion gene that codes for an aberrant chimeric mRNA. Cell lines established from CML patients in blast crisis show higher expression of this aberrant bcr-abl transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fef7f77621940dce013e938e5037a238
https://doi.org/10.1182/blood.v86.6.2371.bloodjournal8662371
https://doi.org/10.1182/blood.v86.6.2371.bloodjournal8662371
Publikováno v:
Europe PubMed Central
Interleukin-15 (IL-15) induces proliferation and promotes cell survival of human T and B lymphocytes, natural killer cells, and neutrophils. Here we report the constitutive expression of a functional IL-15 receptor (IL-15R) in 6 of 6 myeloma cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff63297158c771e052b4a0a4b70cc4ed
https://pubmed.ncbi.nlm.nih.gov/10627470
https://pubmed.ncbi.nlm.nih.gov/10627470
Autor:
Traudl Henn, Oskar A. Haas
Publikováno v:
Diagnostic Cytogenetics ISBN: 9783642478130
CGH is a fluorescence in situ hybridisation (FISH) technique that allows the genome-wide assessment of changes in the relative copy number of chromosome regions in tissues that are not accessible to conventional cytogenetic analysis (Kallioniemi et a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b270e1d0375f092d1da0b6a4bba9478
https://doi.org/10.1007/978-3-642-59918-7_21
https://doi.org/10.1007/978-3-642-59918-7_21
Publikováno v:
Genetic analysis, techniques and applications. 11(5-6)
A series of 80 microclone probes derived from the chromosomal region 1p36 was used to isolate corresponding clones from the ICRF human P1 library (see Francis et al., this issue). Hybridization screenings were performed using probe pools on high-dens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d83f504a1f5efc117fb720a834f6490
https://pubmed.ncbi.nlm.nih.gov/7710779
https://pubmed.ncbi.nlm.nih.gov/7710779
Publikováno v:
Lancet (London, England). 341(8840)
In patients with chronic myelogenous leukaemia (CML) treated by allogeneic bone marrow transplantation (BMT), detection of residual leukaemic cells carrying the characteristic bcr/abl rearrangement by highly sensitive techniques, such as qualitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2475619713a51d25f1db68c1c0bbeae9
https://pubmed.ncbi.nlm.nih.gov/8093920
https://pubmed.ncbi.nlm.nih.gov/8093920