Zobrazeno 1 - 10
of 8 386
pro vyhledávání: '"Transverse aortic constriction (TAC)"'
Autor:
Xinlu Zhang, Ting Feng, Xin-Xin I. Zeng, Hongbin Liang, Bo Situ, Qiuxia Zhang, Fengyun Zhou, Yejia Chen, Tao Wang, Du Cai, Xinxin Lin, Jiancheng Xiu, Lei Zheng
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Arterial remodeling is a major pathological consequence of hypertension, which is recognized as the most common chronic non-communicable disease. However, the detailed mechanism of how arterial remodeling is induced by hypertension has not yet been f
Externí odkaz:
https://doaj.org/article/79fc2ffe511d49c385c42ad945da5b51
Akademický článek
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Autor:
Qiang Wen, Rui Zhang, Kejun Ye, Jun Yang, Hangchuan Shi, Zhu Liu, Yangpeng Li, Ting Liu, Shiyu Zhang, Wanpei Chen, Jingjing Wu, Weichao Liu, Xiaoqiu Tan, Ming Lei, Christopher L.-H. Huang, Xianhong Ou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract We explored physiological effects of the sodium-glucose co-transporter-2 inhibitor empagliflozin on intact experimentally hypertrophic murine hearts following transverse aortic constriction (TAC). Postoperative drug (2–6 weeks) challenge r
Externí odkaz:
https://doaj.org/article/7a7224d6282a486ca9a2c8a589c4d075
Publikováno v:
Clinical and Experimental Hypertension, Vol 45, Iss 1 (2023)
Background Gasdermin D (GSDMD) forms membrane pores to execute pyroptosis. But the mechanism of how cardiomyocyte pyroptosis induces cardiac remodeling in pressure overload remains unclear. We investigated the role of GSDMD-mediated pyroptosis in the
Externí odkaz:
https://doaj.org/article/a6aa200829be422a977724c5050b5245
Autor:
Wen, Qiang1 (AUTHOR), Zhang, Rui2 (AUTHOR), Ye, Kejun2 (AUTHOR), Yang, Jun2 (AUTHOR), Shi, Hangchuan3,4 (AUTHOR), Liu, Zhu2 (AUTHOR), Li, Yangpeng2 (AUTHOR), Liu, Ting2 (AUTHOR), Zhang, Shiyu2 (AUTHOR), Chen, Wanpei2 (AUTHOR), Wu, Jingjing1 (AUTHOR), Liu, Weichao2 (AUTHOR), Tan, Xiaoqiu2 (AUTHOR), Lei, Ming2,5 (AUTHOR), Huang, Christopher L.-H.2,6,7 (AUTHOR) clh11@cam.ac.uk, Ou, Xianhong2,8 (AUTHOR) oxh8081@swmu.edu.cn
Publikováno v:
Scientific Reports. 7/8/2024, Vol. 14 Issue 1, p1-18. 18p.
Publikováno v:
Chinese Journal of Pathophysiology. Feb2024, Vol. 40 Issue 2, p193-203. 11p.
Autor:
Mahito Matsuno, Shunichi Yokoe, Takehiro Nagatsuka, Hirofumi Morihara, Kazumasa Moriwaki, Michio Asahi
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
O-GlcNAc transferase (OGT) modulates many functions of proteins via O-GlcNAcylation that adds O-linked β-N-acetylglucosamine (O-GlcNAc) to the serine/threonine residues of proteins. However, the role of O-GlcNAcylation in cardiac remodeling and func
Externí odkaz:
https://doaj.org/article/da8a0d57575f45aaaab0b8210cb8cc44
Publikováno v:
Journal of Shanghai Jiaotong University (Medical Science). Sep2022, Vol. 42 Issue 9, p1275-1287. 13p.
Akademický článek
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Publikováno v:
Drug Design, Development and Therapy, Vol Volume 14, Pp 5699-5710 (2020)
Xiaohan Xu, Junhong Wang, Xiaowei Wang Department of Cardiovascular Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, People’s Republic of ChinaCorrespondence: Xiaowei WangDepartment of Cardiovascular Surgery,
Externí odkaz:
https://doaj.org/article/3d3d430db8074cfdb764b9263ab63851