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pro vyhledávání: '"Translocase of the outer membrane"'
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Autor:
Sáiz Bonilla, María
[ES] Los virus de plantas son los agentes causales de un gran número de enfermedades en plantas que ocasionan grandes pérdidas económicas. El virus de las manchas necróticas del melón (MNSV), es un pequeño virus de RNA monocatenario de polarida
Externí odkaz:
http://hdl.handle.net/10251/195836
Publikováno v:
Journal of Physiology and Biochemistry. 77:1-11
Dexamethasone augments mitochondrial protein abundance. The translocase of the outer membrane (Tom) of mitochondria plays a major role in importing largely cytosolically synthesized proteins into mitochondria. We hypothesize that dexamethasone upregu
Autor:
Alexander Grevel, Thomas Becker
Publikováno v:
Biological Chemistry. 401:699-708
Mitochondria import the vast majority of their proteins via dedicated protein machineries. The translocase of the outer membrane (TOM complex) forms the main entry site for precursor proteins that are produced on cytosolic ribosomes. Subsequently, di
Autor:
Ian Collinson, Xia Liu, Mark S. Dillingham, Gonçalo C. Pereira, Holly C Ford, William J. Allen
Publikováno v:
Ford, H C, Allen, W J, Pereira, G C, Liu, X, Dillingham, M S & Collinson, I 2022, ' Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes ', eLife, vol. 11, e75426 . https://doi.org/10.7554/eLife.75426
Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting
Autor:
Milana Fraiberg, Boris Macek, Zvulun Elazar, Philipp J. Kahle, Anna Lechado Terradas, Katharina Zittlau
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
Mitochondria are important organelles in eukaryotes. Turnover and quality control of mitochondria are regulated at the transcriptional and posttranslational level by several cellular mechanisms. Removal of defective mitochondrial proteins is mediated
Publikováno v:
Journal of proteomics. 252
A role for reversible phosphorylation in regulation of mitochondrial proteins has been neglected for a long time. Particularly, the import machineries that mediate influx of more than 1000 different precursor proteins into the organelle were consider
Autor:
Tingting Zou, Xiaoqian Cao, Sixing Hong, Jinjin Zhuang, Ping Yin, Ling Yan, Zeyuan Guan, Zhu Liu, Liangbo Qi, Junjie Yan, Qiang Wang, Chen Wang, Chuangye Yan, Yan Wu, Delin Zhang, Jianbo Cao
Publikováno v:
Science (New York, N.Y.). 373(6561)
Barrels that build barrels Cells produce specialized machinery to produce functional β-barrel proteins that are involved in cross-membrane transport and membrane protein biogenesis in eukaryotic organelles and some bacteria. Wang et al . studied one
Autor:
Toshiya Endo, Haruka Sakaue
Publikováno v:
Biochemical Society Transactions. 47:1269-1277
Mitochondria are essential eukaryotic organelles responsible for primary cellular energy production. Biogenesis, maintenance, and functions of mitochondria require correct assembly of resident proteins and lipids, which require their transport into a
Autor:
Thomas Becker, Bettina Warscheid, Nicole Zufall, Kim Nguyen Doan, Jiyao Song, Lars Ellenrieder, Alessia Floerchinger, Silke Oeljeklaus, Felix Boos, Chantal Priesnitz, Christoph U. Mårtensson
Publikováno v:
Nature. 569:679-683
Mitochondrial biogenesis and functions depend on the import of precursor proteins via the 'translocase of the outer membrane' (TOM complex). Defects in protein import lead to an accumulation of mitochondrial precursor proteins that induces a range of