Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Translational attenuation"'
Akademický článek
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Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Ribosome stalling on ermBL at the tenth codon (Asp) is believed to be a major mechanism of ermB induction by erythromycin (Ery). In this study, we demonstrated that the mechanism of ermB induction by Ery depends not only on ermBL expression but also
Externí odkaz:
https://doaj.org/article/1f328e9ca7a242f985ffdd530b526081
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13748
The UPR is sustainably activated in degenerating retinas, leading to translational inhibition via p-eIF2α. Recent findings have demonstrated that ablation of growth arrest and DNA damage-inducible protein 34 (GADD34), a protein phosphatase 1 regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcdbc6a995612e14092d670613379f4
Akademický článek
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Autor:
Martin K. M. Engqvist, Mikael Molin, Veronica Gast, Kate Campbell, Verena Siewers, Cecilia Picazo
Publikováno v:
Applied and Environmental Microbiology. 87
Recombinant protein production is a known source of oxidative stress. However, knowledge of which reactive oxygen species are involved or the specific growth phase in which stress occurs remains lacking. Using modern, hypersensitive genetic H2O2-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be98468ba7c94bc9adf7d4adc2cbeefd
https://doi.org/10.1128/aem.00301-21
https://doi.org/10.1128/aem.00301-21
Autor:
Youn Jung Kim, Jung-Wook Kim, John Timothy Wright, Jan C.-C. Hu, Hong Zhang, Yejin Lee, James P. Simmer
Publikováno v:
Biomedicines, Vol 9, Iss 456, p 456 (2021)
Amelogenesis imperfecta (AI) is a collection of rare genetic conditions affecting tooth enamel. The affected enamel can be of insufficient quantity and/or altered quality, impacting structural content, surface integrity and coloration. Heterozygous m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4248a05492734b5cad3de4d5aeceddc
https://www.mdpi.com/2227-9059/9/5/456
https://www.mdpi.com/2227-9059/9/5/456
Autor:
Vikas Arige, Nitish R. Mahapatra, Ananthamohan Kalyani, S Santosh Reddy, Abrar A. Khan, Heena Agarwal, Manoj Kumar Barthwal, Bhargavi Natarajan, Vinayak Gupta
Publikováno v:
Mol Cell Biol
Hypercholesterolemia is a strong predictor of cardiovascular diseases. The 3-hydroxy-3-methylglutaryl coenzyme A reductase gene (Hmgcr) coding for the rate-limiting enzyme in the cholesterol biosynthesis pathway is a crucial regulator of plasma chole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d04a22850d1c6b46ca22fb153c0e3f
https://doi.org/10.1128/mcb.00470-19
https://doi.org/10.1128/mcb.00470-19
Autor:
Annika Weber, Maximillian M. Dalglish, Jörg Morf, Kim Schneider, Laura M. Luh, Anne Bertolotti, Geoffrey M. Nelson, Joseph L. Watson
Publikováno v:
Cell Reports
Summary Phosphorylation of the translation initiation factor eIF2α is a rapid and vital response to many forms of stress, including protein-misfolding stress in the endoplasmic reticulum (ER stress). It is believed to cause a general reduction in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3cdd37d0779dab380dee3445e71f48
https://pubmed.ncbi.nlm.nih.gov/32937139
https://pubmed.ncbi.nlm.nih.gov/32937139
Autor:
Liliana Comerio, Vanessa Capone, Valentina Grande, Michele Sallese, Francesca Ornaghi, Jeffrey M. Axten, Fabio Fiordaliso, Roberto Chiesa, Nicholas J. Laping, Daniele Tolomeo, Alessandro Corbelli, Antonio Masone, Elena Restelli
Publikováno v:
Human Molecular Genetics. 27:2477-2489
Marinesco-Sjögren syndrome (MSS) is a rare, early onset, autosomal recessive multisystem disorder characterized by cerebellar ataxia, cataracts and myopathy. Most MSS cases are caused by loss-of-function mutations in the gene encoding SIL1, a nucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884ae91cdf092fccbde7f359adfa4a19
https://doi.org/10.1093/hmg/ddy152
https://doi.org/10.1093/hmg/ddy152
Autor:
Hyung Don Ryoo, Deepika Vasudevan
Publikováno v:
BMB Reports
The Integrated Stress Response (ISR) refers to a signaling pathway initiated by stress-activated eIF2α kinases. Once activated, the pathway causes attenuation of global mRNA translation while also paradoxically inducing stress response gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd340718787406166fdfd8ebdbb7cb0c
https://doi.org/10.5483/bmbrep.2017.50.11.157
https://doi.org/10.5483/bmbrep.2017.50.11.157