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pro vyhledávání: '"Translational Therapeutics"'
Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Osteosarcoma is a malignant primary tumor of bone, arising from transformed progenitor cells with osteoblastic differentiation and osteoid production. While categorized as a rare tumor, most patients diagnosed with osteosarcoma are adolescents in the
Externí odkaz:
https://doaj.org/article/b6f1a0df81d247859fdae0aceac0e9a5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Xin Wang, Hong Zhao, Bin S. Teh, Monika Vishnoi, Stephen T. C. Wong, Jenny C. Chang, Robert C. Rostomily, Ding Ren, Hao Cheng
Publikováno v:
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Systemic therapies for primary breast cancer have made great progress over the past two decades. However, oncologists confront an insidious and particularly difficult problem: in those patients with metastatic breast cancer, up to 50% of human epider
Autor:
Yao Lin, A. Robertson, Duncan I. Jodrell, Jo L. Bramhall, Jennifer Harrington, Daniella Zheleva, Tashinga E. Bapiro, Frances M. Richards, B-F Krippendorff
Publikováno v:
British Journal of Cancer
BACKGROUND: Amplification of aurora kinase A (AK-A) overrides the mitotic spindle assembly checkpoint, inducing resistance to taxanes. RNA interference targeting AK-A in human pancreatic cancer cell lines enhanced taxane chemosensitivity. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2a40840c1c7c497781bc2aeb45ad98
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Osteosarcoma is a malignant primary tumor of bone, arising from transformed progenitor cells with osteoblastic differentiation and osteoid production. While categorized as a rare tumor, most patients diagnosed with osteosarcoma are adolescents in the
Publikováno v:
British Journal of Cancer
Background: Adoptive transfer of genetically engineered T-cells to express antigen-specific T-cell receptor (TCR) is a feasible and effective therapeutic approach for numerous types of cancers, including Epstein–Barr virus (EBV)-associated malignan
Autor:
Mei Zhao, Hailong Ma, Shufang Jin, Wen-Yi Yang, Ge Zhou, Jingzhou Hu, Sijie Fang, Zhiyuan Zhang
Publikováno v:
British Journal of Cancer
Background: The epidermal growth factor receptor (EGFR)-targeted therapies have been tested in the clinic as treatments for head and neck squamous cell carcinoma (HNSCC). Owing to intrinsic or acquired resistance, EGFR-targeted therapies often lead t
Autor:
Junnian Zheng, Hong Yao, Zan Shen, Peng-Jin Mei, Gang Wang, Qing Zhang, Hsiangfu Kung, Jian Zhang, Qian Zhang, Wenyan Zhang, Raymond Zhang, Longzhen Zhang, Xiaoge Gao, Marie C. Lin, Mengxue Wei, William K C Cheung, Hong-Lin Chen, Rui Duan
Publikováno v:
British Journal of Cancer
Background: The therapeutic resistance to ionising radiation (IR) and anti-angiogenesis mainly impair the prognosis of patients with glioblastoma. The primary and secondary MET aberrant activation is one crucial factor for these resistances. The krin