Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Translational & Clinical Immunology"'
Autor:
Michael M. Awad, Carlos A. Puyo, Alexander Earhart, Marin H. Kollef, Nicholas Staten, Colleen Haug, Oliver A. Prince
Publikováno v:
Journal of Leukocyte Biology
Tracheitis secondary to placement of an endotracheal tube (ETT) is characterized by neutrophil accumulation in the tracheal lumen, which is generally associated with epithelial damage. Mitochondrial DNA (mtDNA), has been implicated in systemic inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c39c3289ae932ffd6fb4ef3fd7cd9c6
http://europepmc.org/articles/PMC7379990
http://europepmc.org/articles/PMC7379990
Autor:
Xiang-Yang Wang, Harry D. Bear, Laura Graham, Michael O. Idowu, Kyle K. Payne, Rebecca C. Keim, Savannah E. Butler, Wen Wan, Hussein F. Aqbi, Masoud H. Manjili
Publikováno v:
Journal of Leukocyte Biology
Conventional APCs that express MHC class II (MHCII) and co‐stimulatory molecules include dendritic cells (DCs) and macrophages. Beyond these conventional APCs, immune stimulatory cells have been more recently shown to extend to a class of atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f476dfc1782d8aac8fadbd3454e7894
https://doi.org/10.1002/jlb.5a0717-276rr
https://doi.org/10.1002/jlb.5a0717-276rr
Autor:
Jiafeng Zhang, Hao Wu, Elizabeth Ogunrinde, Zhuang Wan, Zejun Zhou, Guoyang Liao, Lei Huang, Zhiqiang Qin, Zhen Li, Tao Zhang, Lei Ma, Sonya L. Heath, Wei Jiang, Lisa Martin, Zhenwu Luo, Tongwen Ou
Publikováno v:
Journal of Leukocyte Biology. 102:1481-1486
Although effective antiretroviral therapy (ART) suppresses HIV viral replication, prevents AIDS-related complications, and prolongs life, a proportion of patients fails to restore the patients’ CD4+ T cell number to the level of healthy individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70e7c1c19372a4472a597ef66f984d0
https://doi.org/10.1189/jlb.5a0617-219r
https://doi.org/10.1189/jlb.5a0617-219r
Autor:
David C. Dale, Vahagn Makaryan, Audrey Anna Bolyard, Merideth L. Kelley, Breanna Fletcher, A. Andrew Aprikyan
Publikováno v:
Journal of Leukocyte Biology. 102:1143-1151
Mutations in ELANE, the gene for neutrophil elastase (NE), a protease expressed early in neutrophil development, are the most frequent cause of cyclic (CyN) and severe congenital neutropenia (SCN). We hypothesized that inhibitors of NE, acting either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a29fe4e0b08754c0ab1819494ca3e0
https://doi.org/10.1189/jlb.5a1016-445r
https://doi.org/10.1189/jlb.5a1016-445r
Autor:
Zhi Q. Yao, Zhan S. Jia, Jonathan P. Moorman, Jun P. Ren, Ying Zhang, Guang Y. Li, Yun Zhou, Chang X. Huang, Shun B. Ning, Jian Q. Lian, Ling Wang, Juan Zhao
Publikováno v:
Journal of Leukocyte Biology. 100:1201-1211
T cell dysfunction has a crucial role in establishing and maintaining viral persistence. We have previously shown a decline in miR-181a, which regulates CD4+ T cell responses via DUSP6 overexpression, in individuals with hepatitis C virus (HCV) infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee946cde1cae30286aeed3112cb6ed74
https://doi.org/10.1189/jlb.5a0316-119rr
https://doi.org/10.1189/jlb.5a0316-119rr
Autor:
Laura Graham, Rebecca C. Keim, Harry D. Bear, Wen Wan, Amir A. Toor, Masoud H. Manjili, Michael O. Idowu, Xiang-Yang Wang, Kyle K. Payne
Publikováno v:
Journal of Leukocyte Biology
Quiescent, but not indolent, dormant tumor cells are resistant to immunoediting, and best targets for immunotherapy of cancer.
Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppre
Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9773d11831054f957ff4c1520ecd7812
http://europepmc.org/articles/PMC4982610
http://europepmc.org/articles/PMC4982610
Autor:
Johan Grunewald, Rico Lepzien, Gregory Rankin, Anders Eklund, Ala Muala, Anna Smed-Sörensen, Jamshid Pourazar, Anders Blomberg
Publikováno v:
Journal of Leukocyte Biology
Sarcoidosis is a T‐cell driven inflammatory disease characterized by granuloma formation. Mononuclear phagocytes (MNPs)—macrophages, monocytes, and dendritic cells (DCs)—are likely critical in sarcoidosis as they initiate and maintain T cell ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09f7771ad7f0267a68f69b816efc1b2
https://pubmed.ncbi.nlm.nih.gov/30742337
https://pubmed.ncbi.nlm.nih.gov/30742337
Autor:
Philippa T. K. Saunders, Hilary O. D. Critchley, Jacqueline A. Maybin, Gregory M. Armstrong, Erin Greaves, Uma Thiruchelvam
Publikováno v:
Journal of Leukocyte Biology
Thiruchelvam, U, Maybin, J A, Armstrong, G M, Greaves, E, Saunders, P T K & Critchley, H O D 2016, ' Cortisol regulates the paracrine action of macrophages by inducing vasoactive gene expression in endometrial cells ', Journal of Leukocyte Biology, vol. 99, no. 6, pp. 440-448 . https://doi.org/10.1189/jlb.5A0215-061RR
Thiruchelvam, U, Maybin, J A, Armstrong, G M, Greaves, E, Saunders, P T K & Critchley, H O D 2016, ' Cortisol regulates the paracrine action of macrophages by inducing vasoactive gene expression in endometrial cells ', Journal of Leukocyte Biology, vol. 99, no. 6, pp. 440-448 . https://doi.org/10.1189/jlb.5A0215-061RR
Cortisol regulation of macrophages induces angiogenic gene expression in endometrial cells at menstruation.
The human endometrium undergoes inflammation and tissue repair during menstruation. We hypothesized that the local availability of bioact
The human endometrium undergoes inflammation and tissue repair during menstruation. We hypothesized that the local availability of bioact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deda7aca7dc74155ded2408b23615402
https://doi.org/10.1189/jlb.5a0215-061rr
https://doi.org/10.1189/jlb.5a0215-061rr
Autor:
Ian Sanne, Matthew Fair, Jocelin Joseph, Luis J. Montaner, Juan Sierra-Madero, Livio Azzoni, Sean C. Patro, Mohammed Rassool
Publikováno v:
Journal of Leukocyte Biology. 100:223-231
Reversal of monocyte and macrophage activation and the relationship to viral suppression and T cell activation are unknown in patients with advanced HIV-1 infection, initiating antiretroviral therapy. This study aimed to determine whether reduction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8854f888a24a4eb4b44d4fe9eb8ac5ad
https://doi.org/10.1189/jlb.5ab0915-406r
https://doi.org/10.1189/jlb.5ab0915-406r
Publikováno v:
Journal of Leukocyte Biology. 99:495-503
The lectin galectin-9 may help establish and maintain chronic hepatitis C virus infection. Galectin-9 is elevated in the liver and sera of hepatitis C virus patients, induces apoptosis of hepatitis C virus-specific T cells, and increases inhibitory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69959803f2c477d949e2e36a3153ee42
https://doi.org/10.1189/jlb.5a1214-582r
https://doi.org/10.1189/jlb.5a1214-582r