Zobrazeno 1 - 10
of 700
pro vyhledávání: '"Translation control"'
Autor:
Rosario Francisco-Velilla, Salvador Abellan, Juan Antonio Garcia-Martin, Juan Carlos Oliveros, Encarnacion Martinez-Salas
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 23-34 (2024)
GEMIN5 is a multifunctional protein involved in various aspects of RNA biology, including biogenesis of snRNPs and translation control. Reduced levels of GEMIN5 confer a differential translation to selective groups of mRNAs, and biallelic variants re
Externí odkaz:
https://doaj.org/article/f01c44795ddc421a916214668f534734
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract Background The design of nucleotide sequences with defined properties is a long-standing problem in bioengineering. An important application is protein expression, be it in the context of research or the production of mRNA vaccines. The rate
Externí odkaz:
https://doaj.org/article/a78a5b201ef04a668d211fb2231ee451
Autor:
Pan Zhao, Lin Xia, Dan Chen, Wei Xu, Huanping Guo, Yinying Xu, Bingbing Yan, Xiao Wu, Yuxia Li, Yunfang Zhang, Xi Zhang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background RNA modifications have been proven to play fundamental roles in regulating cellular biology process. Recently, maladjusted N7-methylguanosine (m7G) modification and its modifiers METTL1/WDR4 have been confirmed an oncogene role in
Externí odkaz:
https://doaj.org/article/c51804a50f0749e4b7d115ad558bdb4e
Autor:
Sara Esther Ramos-Lorente, Beatriz Berzal-Herranz, Cristina Romero-López, Alfredo Berzal-Herranz
Publikováno v:
Virus Research, Vol 343, Iss , Pp 199340- (2024)
Flaviviral RNA genomes are composed of discrete RNA structural units arranged in an ordered fashion and grouped into complex folded domains that regulate essential viral functions, e.g. replication and translation. This is achieved by adjusting the o
Externí odkaz:
https://doaj.org/article/4188eac997214cc1a558923c968b2f73
Publikováno v:
Virus Research, Vol 341, Iss , Pp 199309- (2024)
Newcastle disease virus (NDV) is an avian virus and a promising vector for the development of vaccines for veterinary and human use. The optimal vaccine vector performance requires a stable high-level expression of a transgene. The foreign genes are
Externí odkaz:
https://doaj.org/article/20c42b5747184ad5897f8619b6577a7b
Autor:
Denisa UNGUREAN, Loredana PUNGĂ
Publikováno v:
Scientific Bulletin of the Politehnica University of Timişoara: Transactions on Modern Languages, Vol 22, Iss 1, Pp 65-78 (2023)
This article explores the challenges of setting up a coherent legal translation quality assessment system at a national – Romanian, and international – European level. It begins by providing an overview of the importance of accurate legal transla
Externí odkaz:
https://doaj.org/article/dba9aad5686844f7977fb14801115d11
Autor:
Debjit Khan, Paul L. Fox
Publikováno v:
Viruses, Vol 16, Iss 3, p 468 (2024)
Viruses are obligate, intracellular parasites that co-opt host cell machineries for propagation. Critical among these machineries are those that translate RNA into protein and their mechanisms of control. Most regulatory mechanisms effectuate their a
Externí odkaz:
https://doaj.org/article/35e6ffebdf9c42df8ae28c8dc136c0bb
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract The YTH N 6 -methyladenosine RNA binding proteins (YTHDFs) mediate the functional effects of N 6 -methyladenosine (m6A) on RNA. Recently, a report proposed that all YTHDFs work redundantly to facilitate RNA decay, raising questions about the
Externí odkaz:
https://doaj.org/article/490fa0bda2f6410d87d99b5a1f72bc47
Autor:
Madeline E. Sherlock, Gadareth Higgs, Diane Yu, Danielle L. Widner, Neil A. White, Narasimhan Sudarsan, Harini Sadeeshkumar, Kevin R. Perkins, Gayan Mirihana Arachchilage, Sarah N. Malkowski, Christopher G. King, Kimberly A. Harris, Glenn Gaffield, Ruben M. Atilho, Ronald R. Breaker
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1059-1076 (2022)
Riboswitch architectures that involve the binding of a single ligand to a single RNA aptamer domain result in ordinary dose-response curves that require approximately a 100-fold change in ligand concentration to cover nearly the full dynamic range fo
Externí odkaz:
https://doaj.org/article/d97719da4d29432b890e0c781466c70c
Autor:
Deborah Bell-Pedersen, Kathrina D. Castillo, Teresa M. Lamb, Emily D. Chapa, Madhusree Gangopadhyay
Publikováno v:
F1000Research, Vol 11 (2023)
Background: In Neurospora crassa, the circadian clock controls rhythmic mRNA translation initiation through regulation of the eIF2α kinase CPC-3 (the homolog of yeast and mammalian GCN2). Active CPC-3 phosphorylates and inactivates eIF2α, leading t
Externí odkaz:
https://doaj.org/article/3e12b07c180c4974a51d6d75b5c6c988