Zobrazeno 1 - 10
of 27 145
pro vyhledávání: '"Translation (biology)"'
Autor:
Dermot Harnett, Mateusz C. Ambrozkiewicz, Ulrike Zinnall, Alexandra Rusanova, Ekaterina Borisova, Amelie N. Drescher, Marta Couce-Iglesias, Gabriel Villamil, Rike Dannenberg, Koshi Imami, Agnieszka Münster-Wandowski, Beatrix Fauler, Thorsten Mielke, Matthias Selbach, Markus Landthaler, Christian M. T. Spahn, Victor Tarabykin, Uwe Ohler, Matthew L. Kraushar
Publikováno v:
Nature Structural and Molecular Biology
Translation modulates the timing and amplification of gene expression after transcription. Brain development requires uniquely complex gene expression patterns, but large-scale measurements of translation directly in the prenatal brain are lacking. W
Autor:
Valina L. Dawson, Guo Li Ming, Kimberly M. Christian, Stephanie J. Temme, Weidong Li, Stephen M. Eacker, Kuei Sen Hsu, Stefan Canzar, Ki Jun Yoon, Francisca Rojas Ringeling, Ted M. Dawson, Ha Nam Nguyen, Bo Xiao, Paul F. Worley, Yu Ting Lin, Namshik Kim, Hongjun Song, Ying Zhou
Publikováno v:
Biological Psychiatry. 92:815-826
Background Gene dosage imbalance caused by copy number variations (CNVs) is a prominent contributor to brain disorders. In particular, 15q11.2 CNV duplications and deletions have been associated with autism spectrum disorder and schizophrenia, respec
Autor:
Silvestre I, Sílvia Duarte, Sobral R, Luís Vieira, Alexandra Nunes, João Paulo Gomes, Borges, Maria José Borrego
Publikováno v:
Cellular and Molecular Biology. 68:1-8
Streptococcus agalactiae is a leading cause of neonatal infections and an increasing cause of infections in adults with underlying diseases. One of the first S. agalactiae isolates to be subjected to whole genome sequencing was NEM316, a strain respo
Autor:
Luigi Cristiano
Publikováno v:
Genes & Diseases. 9:941-958
The eukaryotic translation elongation factors (EEFs), i.e. EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1G, EEF1E1 and EEF2, are coding-genes that play a central role in the elongation step of translation but are often altered in cancer. Less investigated are t
Publikováno v:
Methods
Enzymatic modification of the 5′-cap is a versatile approach to modulate the properties of mRNAs. Transfer of methyl groups from S-adenosyl- l -methionine (AdoMet) or functional moieties from non-natural analogs by methyltransferases (MTases) allow
Autor:
Felix Naef, Cédric Gobet
Publikováno v:
Methods. 203:10-16
Protein synthesis is an energy consuming process characterised as a pivotal and highly regulated step in gene expression. The net protein output is dictated by a combination of translation initiation, elongation and termination rates that have remain
Publikováno v:
Nat Struct Mol Biol
Organismal growth and development rely on RNA Polymerase II (RNAPII) synthesizing the appropriate repertoire of messenger RNAs (mRNAs) from protein-coding genes. Productive elongation of full-length transcripts is essential for mRNA function, however
Autor:
Sadia Belkhir
Publikováno v:
Cognitive Linguistic Studies. 9:110-127
Metaphoric proverbs represent interesting cultural instances of conventional metaphors (Belkhir 2014, 2012). The ubiquity of metaphoric proverbs in language and the problems this phenomenon causes in translation is an issue that requires close attent
Publikováno v:
Nucleic Acids Research. 50:5029-5046
Bacterial mRNAs have short life cycles, in which transcription is rapidly followed by translation and degradation within seconds to minutes. The resulting diversity of mRNA molecules across different life-cycle stages impacts their functionality but
Autor:
Mauricio M. Oliveira, Eric Klann
Publikováno v:
Semin Cell Dev Biol
Memory storage is a conserved survivability feature, present in virtually any complex species . During the last few decades, much effort has been devoted to understanding how memories are formed and which molecular switches define whether a memory sh