Zobrazeno 1 - 10
of 1 340
pro vyhledávání: '"Transglutaminase 2"'
Autor:
Yurika Ninomiya, Shinji Matsuda, Shigeki Suzuki, Shizu Hirata-Tsuchiya, Tomoya Ueda, Fuminori Nakashima, Keisuke Yasuda, Shogo Shimada, Takumi Memida, Tetsuya Yoshimoto, Satoru Yamada, Kazuhisa Ouhara, Noriyoshi Mizuno
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background This study aimed to elucidate the pathogenesis of idiopathic gingival fibromatosis (IGF). Methods Human gingival fibroblasts (hGFs) were isolated from patients with IGF and periodontitis. Differential gene expression in the hGFs w
Externí odkaz:
https://doaj.org/article/dac052aecf2d49e993a57583e0d1c692
Publikováno v:
陆军军医大学学报, Vol 46, Iss 19, Pp 2188-2196 (2024)
Objective To explore the role and mechanism of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) overexpressing transglutaminase 2 (TGM2) in lactate-mediated oxidative stress-induced apoptosis in nucleus pulposus cells. Methods Twenty
Externí odkaz:
https://doaj.org/article/016f55e7057e4a98b6a5c31d416b3a15
Autor:
Ibrahim Wichka, Pin-Kuang Lai
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3669-3679 (2024)
Celiac disease poses a significant health challenge for individuals consuming gluten-containing foods. While the availability of gluten-free products has increased, there is still a need for therapeutic treatments. The advancement of computational dr
Externí odkaz:
https://doaj.org/article/cf856de826aa42019b81ec5742025b4b
Autor:
Bo Liu, Zhiyuan Cai, Yan Wang, Xinye Liu, Bin Zhang, Qian Zheng, Jingye Li, Cien Li, Yuanbo Cui, Pengju Lv, Dongwei Yang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionEndothelial cell (EC) calcification is an important marker of atherosclerotic calcification. ECs play a critical role not only in atherogenesis but also in intimal calcification, as they have been postulated to serve as a source of osteop
Externí odkaz:
https://doaj.org/article/42ba8f256ccf46ac8415e78fe042252f
Autor:
Mengxin Li, Xuanzhong Wang, Jinghui Hong, Juanjuan Mao, Jiasi Chen, Xuyang Chen, Ye Du, Dong Song
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Transglutaminase 2 (TG2) is a widely distributed multifunctional protein with various enzymatic and non-enzymatic activities. It is becoming increasingly evident that high levels of TG2 in tumors induce the occurrence of epithelial to mesenchymal tra
Externí odkaz:
https://doaj.org/article/b5051f406cf6472e856d8a9b1df5fb6e
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4251-4270 (2024)
Hepatocellular carcinoma (HCC) is a heterogeneous malignancy with complex carcinogenesis. Although there has been significant progress in the treatment of HCC over the past decades, drug resistance to chemotherapy remains a major obstacle in its succ
Externí odkaz:
https://doaj.org/article/7ffad542163f4609896d1b815cbb9e4c
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103438- (2024)
RAS-selective lethal small molecule 3 (RSL3) is a small-molecule compound that triggers ferroptosis by inactivating glutathione peroxidase 4. However, its effect on the radioresistance of glioma cells and the underlying mechanisms remains unclear. In
Externí odkaz:
https://doaj.org/article/29a2821395b948d185628bd746754e15
Akademický článek
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Autor:
Ergülen Elvan, Akdoğan Güner Gül
Publikováno v:
Türk Biyokimya Dergisi, Vol 49, Iss 2, Pp 289-295 (2024)
Transglutaminase 2 (TG2) is a unique protein having enzymatic and nonenzymatic functions that have been implicated in various biological and pathological processes such as cell survival and apoptosis, cell signaling, differentiation, adhesion and mig
Externí odkaz:
https://doaj.org/article/4d3a52e05550461398bd7d049ae8f81a
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 4, Pp 31-46 (2023)
In normal tissue, cellular homeostasis is largely driven by two catabolic pathways: apoptosis and autophagy. Apoptosis, or programmed cell death, is regulated by pro-apoptotic factors, and promotes the removal of problematic cells. Autophagy, which i
Externí odkaz:
https://doaj.org/article/8e488d380d6e4393a810e0fd77f33f96