Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Transepithelial permeability"'
Publikováno v:
AMB Express, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract In 2009, the FDA approved bevacizumab for the treatment of adult patients diagnosed with recurrent glioblastoma. However, the poor permeability of the macromolecules across the blood–brain barrier, determined by multifactorial anatomical a
Externí odkaz:
https://doaj.org/article/a9be7bb6c90a47a287ee4b57302bcebe
Synthesis of taurine–fluorescein conjugate and evaluation of its retina-targeted efficiency in vitro
Autor:
Meihong Huang, Jiaqi Song, Bingzheng Lu, Huizhi Huang, Yizhen Chen, Wei Yin, Wenbo Zhu, Xinwen Su, Chuanbin Wu, Haiyan Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 6, Pp 447-453 (2014)
In this work, retinal penetration of fluorescein was achieved in vitro by covalent attachment of taurine to fluorescein, yielding the F–Tau conjugate. Nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HRMS) were used to confir
Externí odkaz:
https://doaj.org/article/20f0a2ba471d49abb6f1b54719ffb9ee
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 43, Iss 4, Pp 330-337 (2010)
The objectives of this study were to determine the effect of tumor necrosis factor alpha (TNF-α) on intestinal epithelial cell permeability and the expression of tight junction proteins. Caco-2 cells were plated onto Transwell® microporous filters
Externí odkaz:
https://doaj.org/article/c94a9dd168644788874d1ed296a214e8
Autor:
Paula Veríssimo, Ricardo Gaspar, Euclides Pires, Ana Todo-Bom, Luísa Cortes, Mafalda Ramos de Matos, Isabel Nunes-Correia
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 10
International Journal of Molecular Sciences, Vol 21, Iss 3578, p 3578 (2020)
Volume 21
Issue 10
International Journal of Molecular Sciences, Vol 21, Iss 3578, p 3578 (2020)
Allergic diseases are a major health concern worldwide. Pollens are important triggers for allergic rhinitis, conjunctivitis and asthma. Proteases released upon pollen grain hydration appear to play a major role in the typical immunological and infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e0cfb1eaf8521381afbc65af359a7f
Publikováno v:
Therapeutic Delivery. 6:1365-1376
Effective drug delivery to the eye is an ongoing challenge due to poor patient compliance coupled with numerous physiological barriers. Eye drops for the front of the eye and ocular injections for the back of the eye are the most prevalent delivery m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f332b7f1f1fdfe88e222d4ec5bf1e1c
https://doi.org/10.4155/tde.15.75
https://doi.org/10.4155/tde.15.75
Akademický článek
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Synthesis of taurine–fluorescein conjugate and evaluation of its retina-targeted efficiency in vitro
Autor:
Yizhen Chen, Huizhi Huang, Jiaqi Song, Meihong Huang, Chuanbin Wu, Bingzheng Lu, Xinwen Su, Wei Yin, Haiyan Hu, Wenbo Zhu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 6, Pp 447-453 (2014)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
In this work, retinal penetration of fluorescein was achieved in vitro by covalent attachment of taurine to fluorescein, yielding the F–Tau conjugate. Nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HRMS) were used to confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc13711d1d4694c69b8faa850210f179
http://www.sciencedirect.com/science/article/pii/S2211383514001051
http://www.sciencedirect.com/science/article/pii/S2211383514001051
Akademický článek
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Akademický článek
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Publikováno v:
Current Eye Research. 37:234-238
To investigate the influence of osmolarity on the transepithelial permeability of riboflavin solutions in a cross-linking procedure.Several riboflavin 0.1% solutions that contained different NaCl and benzalkonium chloride (BAC) concentrations were ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edfcbd07dae001fa8e161c6e8a32caf
https://doi.org/10.3109/02713683.2011.637656
https://doi.org/10.3109/02713683.2011.637656