Zobrazeno 1 - 10 of 377 pro vyhledávání: '"Transdução de Sinal"'
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Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells
Autor: Márcia Faria, José Vareda, Micaella Miranda, Maria João Bugalho, Ana Luísa Silva, Paulo Matos
Publikováno v: Cancers; Volume 14; Issue 21; Pages: 5362
This article belongs to the Special Issue Thyroid Carcinoma While most cases of differentiated thyroid carcinoma (DTC) are associated with a good prognosis, a significant number progress to advanced disease exhibiting aggressive clinical characterist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dca6535249773983bb36e5516856a77
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3
Akademický článek
Overview of the biochemical and genetic processes in malignant mesothelioma
Autor: Leonardo Vinícius Monteiro de Assis, Mauro César Isoldi
Publikováno v: Jornal Brasileiro de Pneumologia, Vol 40, Iss 4, Pp 429-442 (2014)
Malignant mesothelioma (MM) is a highly aggressive form of cancer, has a long latency period, and is resistant to chemotherapy. It is extremely fatal, with a mean survival of less than one year. The development of MM is strongly correlated with expos
Externí odkaz: https://doaj.org/article/754d37f0db8f41b39712701a3a12e887
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4
Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia
Autor: Mariana Lazarini, Letícia V. Costa-Lotufo, Hugo Passos Vicari, Keli Lima, Fabiola Traina, Jean Carlos Lipreri da Silva, Juan L Coelho-Silva, João Agostinho Machado-Neto
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Despite great advances that have been made in the understanding of the molecular complexity of acute myeloid leukemia (AML), very little has been translated into new therapies. Here, we set out to investigate the impact of cytoskeleton regulatory gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f8e88b1df83997bbe8fbd11d4e0a07
https://doi.org/10.1007/s13402-021-00621-0
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5
A Signaling View into the Inflammatory Tumor Microenvironment
Autor: Peter Jordan, Joana Pereira, Paulo Matos
Publikováno v: Immuno, Vol 1, Iss 7, Pp 91-118 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The development of tumors requires an initiator event, usually exposure to DNA damaging agents that cause genetic alterations such as gene mutations or chromosomal abnormalities, leading to deregulated cell proliferation. Although the mere stochastic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289e96f6d0f73d26ad2b7e98e4ede9bf
https://www.mdpi.com/2673-5601/1/2/7
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6
Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways
Autor: Waldiceu A. Verri, Leonardo N. Seito, Maria das Graças M. O. Henriques, Luana Barbosa Correa, Elaine Cruz Rosas, Marília F. Manchope, Thiago M. Cunha
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Methyl gallate (MG) is a prevalent polyphenol in the plant kingdom, which may be related to the effects of several medicinal plants. Although it is widely reported that polyphenols have therapeutic effects, there are few studies demonstrating that MG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786b2dfd0cd25ca6936de621b85d4750
https://doi.org/10.1007/s00011-020-01407-0
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7
Cytotoxicity and genotoxicity of MWCNT-7 and crocidolite: assessment in alveolar epithelial cells versus their coculture with monocyte-derived macrophages
Autor: Bárbara Marques, Paulo Matos, António Sousa-Uva, Peter Jordan, Joana Pereira, Célia Ventura, Maria João Silva
Publikováno v: Nanotoxicology. 14:479-503
In the past years, several in vitro studies have addressed the pulmonary toxicity of multi-walled carbon nanotubes (MWCNT) and compared it with that caused by asbestos fibers, but their conclusions have been somewhat inconsistent and difficult to ext
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4a78c45c8b7b550037638fcee9a726
https://doi.org/10.1080/17435390.2019.1695975
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8
Pro-Inflammatory Cytokines Trigger the Overexpression of Tumour-Related Splice Variant RAC1B in Polarized Colorectal Cells
Autor: Joana F. S. Pereira, Cláudia Bessa, Paulo Matos, Peter Jordan
Publikováno v: Cancers; Volume 14; Issue 6; Pages: 1393
Simple Summary: Tumours are now known to develop more quickly when the tumour cell mass is located in a tissue that shows signs of chronic inflammation. Under such conditions, inflammatory cells from the surrounding tumour microenvironment provide su
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74229f81ce6bd30c49cfbfbf5f4e9cce
https://hdl.handle.net/10400.18/8432
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9
Effect of Aflatoxin B1 in both Caco-2 and Caco-2/HT29-MTX models
Autor: Serrenho, I., Vidal, N., Rolo, D., Louro, H., Pereira, J., Matos, P., Jordan, P., Alvito, P.
About effect of Aflatoxin B1 in both Caco-2 and Caco-2/HT29-MTX models within the scope of the intestinal absorption assessment and enabling formulations. FCT/MCTES for funding with national funds related to theearlyMYCO project (PTDC/MED-TOX/28762/2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2016::893ab2673b00b2d5722a65d911ea22f3
https://hdl.handle.net/10400.18/8251
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10
Akademický článek
Signal transduction in Plasmodium-Red Blood Cells interactions and in cytoadherence
Autor: Laura N. Cruz, Yang Wu, Alister G. Craig, Célia R.S. Garcia
Publikováno v: Anais da Academia Brasileira de Ciências, Vol 84, Iss 2, Pp 555-572 (2012)
Malaria is responsible for more than 1.5 million deaths each year, especially among children (Snow et al. 2005). Despite of the severity of malaria situation and great effort to the development of new drug targets (Yuan et al. 2011) there is still a
Externí odkaz: https://doaj.org/article/29b3f8f4fb424ab584dd124affa1f405
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