Zobrazeno 1 - 10
of 644
pro vyhledávání: '"Transcutaneous immunization"'
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractConventional treatments for tumors were frequently accompanied by drawbacks and side effects. It might be useful to use the revolutionary microneedle technology which combines photothermal therapy with tumor immunotherapy. In this study, we c
Externí odkaz:
https://doaj.org/article/4b47241c56754996a920167b52393fa4
Autor:
Joschka Bartneck, Ann-Kathrin Hartmann, Lara Stein, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Federico Marini, Jonas Pielenhofer, Sophie Luise Meiser, Peter Langguth, Matthias Mack, Sabine Muth, Hans-Christian Probst, Hansjörg Schild, Markus Philipp Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor development and progression is shaped by the tumor microenvironment (TME), a heterogeneous assembly of infiltrating and resident host cells, their secreted mediators and intercellular matrix. In this context, tumors are infiltrated by various i
Externí odkaz:
https://doaj.org/article/b6b81cbb0f6c4c90b928a7619a5c1a38
Akademický článek
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Autor:
Aihua Wu, Yingzhi Chen, Hairui Wang, Ya Chang, Meng Zhang, Pengfei Zhao, Yisi Tang, Qin Xu, Zhuangzhi Zhu, Yang Cao, Yongzhuo Huang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3622-3635 (2021)
An essential step for cancer vaccination is to break the immunosuppression and elicit a tumor-specific immunity. A major hurdle against cancer therapeutic vaccination is the insufficient immune stimulation of the cancer vaccines and lack of a safe an
Externí odkaz:
https://doaj.org/article/eda5c3f270624e1ebbeea6bba12704d1
Akademický článek
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Autor:
Momo Kamei, Kazuhiko Matsuo, Haruka Imanishi, Yuta Hara, Ying-Shu Quen, Fumio Kamiyama, Naoki Oiso, Akira Kawada, Naoki Okada, Takashi Nakayama
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 3, Pp 182-187 (2020)
Memory CD8+ cytotoxic T-lymphocytes (CTLs) play a key role in protective immunity against infection and cancer. However, the induction of memory CTLs with currently available vaccines remains difficult. The chemokine receptor XCR1 is predominantly ex
Externí odkaz:
https://doaj.org/article/6de5574a618a41fa85bc6d011c3aa815
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Transcutaneous immunization (TCI) via needle-free and non-invasive drug delivery systems is a promising approach for overcoming the current limitations of conventional parenteral vaccination methods. The targeted access to professional antigen-presen
Externí odkaz:
https://doaj.org/article/9c4e4b8a3676434b9acaaddaa753823d
Autor:
Sachiko Hirobe, Taki Yamasaki, Sayami Ito, Ying-Shu Quan, Fumio Kamiyama, Masashi Tachibana, Naoki Okada
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 385 (2022)
We are interested in promoting the development of transcutaneous immunization using microneedle technology and attempting to apply an adjuvant with transcutaneous immunization to improve the efficacy and reduce the amount of antigen and number of adm
Externí odkaz:
https://doaj.org/article/976aa4da38cb4633a9b2a0669c5e2124
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1480 (2021)
In this study, we investigated the mechanism of transcutaneous adjuvant activity of the CpG-oligonucleotide (K3) in mice. Transcutaneous immunization (TCI) with an ovalbumin-loaded self-dissolving microneedle patch (OVA-sdMN) and K3-loaded hydrophili
Externí odkaz:
https://doaj.org/article/380281181acc4e6394f5451dbaba5e21
Akademický článek
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