Zobrazeno 1 - 10
of 1 880
pro vyhledávání: '"Transcriptional silencing"'
Autor:
Josephine Rybchuk, Wei Xiao
Publikováno v:
mLife, Vol 3, Iss 2, Pp 207-218 (2024)
Abstract The Saccharomyces cerevisiae silencing information regulator (SIR) complex contains up to four proteins, namely Sir1, Sir2, Sir3, and Sir4. While Sir2 encodes a NAD‐dependent histone deacetylase, other SIR proteins mainly function as struc
Externí odkaz:
https://doaj.org/article/d318388b64cf4dc3959f7c91e073d9e5
Autor:
Paraskevi Kallemi, Frederic Verret, Christos Andronis, Nikolaos Ioannidis, Nikolaos Glampedakis, Kiriakos Kotzabasis, Kriton Kalantidis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Plants respond to biotic and abiotic stress by activating and interacting with multiple defense pathways, allowing for an efficient global defense response. RNA silencing is a conserved mechanism of regulation of gene expression directed by
Externí odkaz:
https://doaj.org/article/aa18c61211474f9aacada2e5c2c8c98f
Autor:
Stephen P. Goff
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
The unintegrated HIV-1 DNAs formed by reverse transcription in the early hours after infection are subject to profound transcriptional silencing. The repression of expression of foreign DNA, as an aspect of the innate immune system, serves to restric
Externí odkaz:
https://doaj.org/article/4efb43aa91e44297b215972e7b971f82
Autor:
Miqdam M. Obaid AL-Jumaili
Publikováno v:
The Korean Journal of Gastroenterology, Vol 83, Iss 1, Pp 6-16 (2024)
Background/Aims: Colorectal cancer is the most common cancer in oncopathology, with an increasing incidence among the elderly during the last decade. Various genetic and environmental factors play important roles in the emergence of colorectal adenoc
Externí odkaz:
https://doaj.org/article/b97a856e8a8f4a91820c6f148b21af1f
Publikováno v:
Viruses, Vol 16, Iss 5, p 764 (2024)
The hepatitis B virus (HBV) infects hepatocytes and hijacks host cellular mechanisms for its replication. Host proteins can be frontline effectors of the cell’s defense and restrict viral replication by impeding multiple steps during its intracellu
Externí odkaz:
https://doaj.org/article/249a04dd8e184ee8acb66971ab7e0917
Autor:
Taylor M. Gerson, Audrey M. Ott, Monika M. A. Karney, Jillian N. Socea, Daren R. Ginete, Lakshminarayan M. Iyer, L. Aravind, Ronald K. Gary, Helen J. Wing
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without virB, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional
Externí odkaz:
https://doaj.org/article/fc3cc248550549869b8473588cb9be2a
Publikováno v:
Viruses, Vol 16, Iss 5, p 714 (2024)
Transposons are integral genome constituents that can be domesticated for host functions, but they also represent a significant threat to genome stability. Transposon silencing is especially critical in the germline, which is dedicated to transmittin
Externí odkaz:
https://doaj.org/article/21b20277764b495895d8f95176f49d5b
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Akademický článek
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Autor:
A.E. Abaturov, V.L. Babуch
Publikováno v:
Zdorovʹe Rebenka, Vol 17, Iss 5, Pp 256-261 (2022)
This scientific review deals with the mechanisms of action of cytoplasmic microRNAs, namely post-transcriptional silencing: recruitment of the DCP1-DCP2 decapping complex and disruption of the interaction of mRNA with ribosomes. To write the article,
Externí odkaz:
https://doaj.org/article/bf47f04139f349b795e4a8785ba747d4