Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Transcriptional rewiring"'
Publikováno v:
eLife, Vol 12 (2023)
The GAL pathway of yeasts has long served as a model system for understanding of how regulatory mode of eukaryotic metabolic pathways evolves. While Gal4 mode has been well-characterized in Saccharomycetaceae clade, little is known about the regulati
Externí odkaz:
https://doaj.org/article/96c367eead9848cea1a9de0cac7fb9d1
Akademický článek
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Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Candida albicans is a commensal member of the human microbiota that colonizes multiple niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary tracts of healthy individuals. It is also the most common human fungal p
Externí odkaz:
https://doaj.org/article/f9fb9ac62c054d9abad91db3f9478574
Autor:
Jose L Orgaz, Victoria Sanz-Moreno
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 3 (2020)
Myosin II and its regulator Rho-associated coiled-coil containing protein kinase (ROCK) are essential for cell invasion and metastatic dissemination. Our recent findings show that this molecular machinery is also involved in drug resistance in melano
Externí odkaz:
https://doaj.org/article/7f997344a0564fe9b058fff5a433b77e
Autor:
Manfred Schartl, Susanne Schories, Yuko Wakamatsu, Yusuke Nagao, Hisashi Hashimoto, Chloé Bertin, Brigitte Mourot, Cornelia Schmidt, Dagmar Wilhelm, Lazaro Centanin, Yann Guiguen, Amaury Herpin
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background Sex determination relies on a hierarchically structured network of genes, and is one of the most plastic processes in evolution. The evolution of sex-determining genes within a network, by neo- or sub-functionalization, also requi
Externí odkaz:
https://doaj.org/article/d2e711a503d541508902dfa7584ed90c
Autor:
Tzu-Chiao Lu, Jun-Yi Leu, Chia-Wei Liao, Ahmed A. A. Amine, Yu-Ting Jhou, Po-Chen Hsu, Po-Hsiang Hung
Publikováno v:
Molecular Biology and Evolution
Prior and extensive plastic rewiring of a transcriptional network, followed by a functional switch of the conserved transcriptional regulator, can shape the evolution of a new network with diverged functions. The presence of three distinct iron regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3871725bd24fcef344c2418e38d0a1c2
https://doi.org/10.1093/molbev/msab192
https://doi.org/10.1093/molbev/msab192
Akademický článek
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Autor:
Chiraj K Dalal, Ignacio A Zuleta, Kaitlin F Mitchell, David R Andes, Hana El-Samad, Alexander D Johnson
Publikováno v:
eLife, Vol 5 (2016)
Evolutionary changes in transcription networks are an important source of diversity across species, yet the quantitative consequences of network evolution have rarely been studied. Here we consider the transcriptional ‘rewiring’ of the three GAL
Externí odkaz:
https://doaj.org/article/02c1cf5216aa42ed90e79cd2431e22b2
Publikováno v:
Journal of molecular biology. 433(15)
Genetics is at the basis of cancer initiation and evolution, but emerging evidence indicates that mutations are not sufficient to produce cancer, indicating a role for epigenetic contributions to the different stages of tumorigenesis. While the genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316a4f65e92f47a2024a8dd462d299ce
https://pubmed.ncbi.nlm.nih.gov/34119490
https://pubmed.ncbi.nlm.nih.gov/34119490
Autor:
Jose L. Orgaz, Victoria Sanz-Moreno
Publikováno v:
DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Molecular & Cellular Oncology
Universidad Francisco de Vitoria
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Molecular & Cellular Oncology
Myosin II and its regulator Rho-associated coiled-coil containing protein kinase (ROCK) are essential for cell invasion and metastatic dissemination. Our recent findings show that this molecular machinery is also involved in drug resistance in melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7939c8c55314b03d8610f4b0770518
http://hdl.handle.net/10641/2302
http://hdl.handle.net/10641/2302
