Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Transcription Factors - biosynthesis"'
Autor:
Ivan Stamenkovic, Miguel Rivera, Angela Volorio, Sowmya Iyer, Liliane C. Broye, Nicolo Riggi, Gaylor Boulay
Publikováno v:
Genes & development, vol. 32, no. 15-16, pp. 1008-1019
Various types of repetitive sequences are dysregulated in cancer. In Ewing sarcoma, the oncogenic fusion protein EWS-FLI1 induces chromatin features typical of active enhancers at GGAA microsatellite repeats, but the function of these sites has not b
Autor:
Veerle Baert, H. Joseph Yost, Nathalie Jurisch-Yaksi, Przemko Tylzanowski, Tim Raemaekers, Applonia Josephine Rose, Guy Froyen, Wendy Vermeire, Cammon B. Arrington, Huiqi Lu, Roel Vandepoel, Emre Yaksi, Daphne Verleyen, Wim Annaert, Pieter Baatsen, Sebastian Munck, Thomy de Ravel, Suzie J. Scales
Publikováno v:
The Journal of Cell Biology
Rer1p is an ER/cis-Golgi membrane protein that maintains ciliary length and function by reducing γ-secretase complex assembly and activity (thereby balancing Notch signaling) and increasing Foxj1a expression.
Cilia project from the surface of m
Cilia project from the surface of m
Autor:
Walter L. Eckalbar, Jingjing Zhao, Betty M. Booker, Katherine S. Pollard, Nicola Illing, Malcolm Logan, Mandy K. Mason, Nadav Ahituv, Tara Friedrich, Julia E. VanderMeer
Publikováno v:
PLOS Genetics
Booker, B M, Friedrich, T, Mason, M K, VanderMeer, J E, Zhao, J, Eckalbar, W L, Logan, M, Illing, N, Pollard, K S & Ahituv, N 2016, ' Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus ', PL o S Genetics, vol. 12, no. 3, pp. e1005738 . https://doi.org/10.1371/journal.pgen.1005738
PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005738 (2016)
Booker, B M, Friedrich, T, Mason, M K, VanderMeer, J E, Zhao, J, Eckalbar, W L, Logan, M, Illing, N, Pollard, K S & Ahituv, N 2016, ' Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus ', PL o S Genetics, vol. 12, no. 3, pp. e1005738 . https://doi.org/10.1371/journal.pgen.1005738
PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005738 (2016)
The molecular events leading to the development of the bat wing remain largely unknown, and are thought to be caused, in part, by changes in gene expression during limb development. These expression changes could be instigated by variations in gene r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6b7d3c13dfd52f2547c73b7d6067ac
http://hdl.handle.net/11427/18857
http://hdl.handle.net/11427/18857
Autor:
Dorothée Caille, Romano Regazzi, E. Roggli, Sonia Gattesco, Christian Boitard, Paolo Meda, Claire Briet
Publikováno v:
Diabetes, vol. 61, no. 7, pp. 1742-1751
Diabetes
Diabetes
During the initial phases of type 1 diabetes, pancreatic islets are invaded by immune cells, exposing β-cells to proinflammatory cytokines. This unfavorable environment results in gene expression modifications leading to loss of β-cell functions. T
Autor:
Paul Schedl, Fisun Hamaratoglu, David Requena, Dimitri Bieli, Carlos Estella, Matthew Slattery, Oguz Kanca, Daryl M. Gohl, Markus Affolter, Martin Müller
Publikováno v:
Plos Genetics, vol. 11, no. 10, pp. e1005376
PLoS Genetics, Vol 11, Iss 10, p e1005376 (2015)
PLoS Genetics
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
PLoS Genetics, Vol 11, Iss 10, p e1005376 (2015)
PLoS Genetics
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
The subdivision of cell populations in compartments is a key event during animal development. In Drosophila, the gene apterous (ap) divides the wing imaginal disc in dorsal vs ventral cell lineages and is required for wing formation. ap function as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e43ebfbb4f0711adea81663e64d3c7
https://orca.cardiff.ac.uk/id/eprint/118484/1/journal.pgen.1005376.PDF
https://orca.cardiff.ac.uk/id/eprint/118484/1/journal.pgen.1005376.PDF
Autor:
Stéphane König, Laurent Bernheim, Serge Arnaudeau, Nicolas Holzer, Charles R. Bader, Gael Potter, Valérie Hinard
Publikováno v:
Journal of Biological Chemistry, Vol. 279, No 27 (2004) pp. 28187-28196
It is widely thought that myogenin is one of the earliest detectable markers of skeletal muscle differentiation. Here we show that, during human myoblast differentiation, an inward rectifier K(+) channel (Kir2.1) and its associated hyperpolarization
Autor:
Maejima, T., Inoue, T., Kanki, Y., Kohro, T., Li, G., Ohta, Y., Kimura, Hiroshi, Kobayashi, M., Taguchi, A., Tsutsumi, S., Iwanari, H., Yamamoto, S., Aruga, H., Dong, S., Stevens, J. F., Poh, H. M., Yamamoto, K., Kawamura, T., Mimura, I., Suehiro, J., Sugiyama, A., Kaneki, K., Shibata, H., Yoshinaka, Y., Doi, T., Asanuma, A., Tanabe, S., Tanaka, T., Minami, T., Hamakubo, T., Sakai, J., Nozaki, N., Aburatani, H., Nangaku, M., Ruan, X., Tanabe, H., Ruan, Y., Ihara, S., Endo, A., Kodama, T., Wada, Y.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e96005 (2014)
PLoS ONE, Vol 9, Iss 5, p e96005 (2014)
Statins exert atheroprotective effects through the induction of specific transcriptional factors in multiple organs. In endothelial cells, statin-dependent atheroprotective gene up-regulation is mediated by Kruppel-like factor (KLF) family transcript
Publikováno v:
Proceedings of the National Academy of Sciences. 98:6180-6185
Tissue remodeling often reflects alterations in local mechanical conditions and manifests as an integrated response among the different cell types that share, and thus cooperatively manage, an extracellular matrix. Here we examine how two different c
Autor:
Frédérique Brockly, Tiphanie Gomard, Tamara Salem, Gabriel Moquet-Torcy, Thierry Forné, Franck Court, Marc Piechaczyk
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2013, 41 (19), pp.8908--25. ⟨10.1093/nar/gkt669⟩
Nucleic Acids Research, Oxford University Press, 2013, 41 (19), pp.8908--25. ⟨10.1093/nar/gkt669⟩
The junb gene behaves as an immediate early gene in bacterial lipopolysaccharide (LPS)-stimulated dendritic cells (DCs), where its transient transcriptional activation is necessary for the induction of inflammatory cytokines. junb is a short gene and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3340518e974068323ac67f3d49c5d0fb
https://hal.archives-ouvertes.fr/hal-02193675
https://hal.archives-ouvertes.fr/hal-02193675
Autor:
Philippe Lewalle, Pedro Romero, Redouane Rouas, Makram Merimi, Philippe Martiat, Hussein Fayyad-Kazan, Bassam Badran, Arsène Burny, Eva Hamade, Nabil El Zein, Rabih Badran, Mohammad Fayyad-Kazan, Fadi Jebbawi, Medhi Najar
Publikováno v:
The Journal of biological chemistry, 287 (13
Regulatory T cells (Tregs) are characterized by a high expression of IL-2 receptor α chain (CD25) and of forkhead box P3 (FOXP3), the latter being essential for their development and function. Another major player in the regulatory function is the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bf37050da1f9d75630bfbd500152df
https://europepmc.org/articles/PMC3365745/
https://europepmc.org/articles/PMC3365745/