Výsledky vyhledávání - "Transcription Factors/ genetics/metabolism/ physiology"

New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study

Autor: Emmanuèle Barras, Walter Reith, Madeleine Zufferey, Michal Krawczyk, Krzysztof Masternak

Publikováno v: Molecular and Cellular Biology, Vol. 25, No 19 (2005) pp. 8607-8618

The transcription factors RFX and CIITA are major players in regulation of the expression of all classical and nonclassical major histocompatibility complex class II (MHC-II) genes. RFX nucleates the formation of a multiprotein complex, called the MH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02ca9c7733e753201efa83acf4cc818
https://pubmed.ncbi.nlm.nih.gov/16166641

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Expression of the Three Human Major Histocompatibility Complex Class II Isotypes Exhibits a Differential Dependence on the Transcription Factor RFXAP

Autor: Jean Villard, Madeleine Zufferey, Marie Peretti, Emmanuèle Barras, Walter Reith

Publikováno v: Molecular and Cellular Biology, Vol. 21, No 17 (2001) pp. 5699-5709

Major histocompatibility complex class II (MHCII) molecules play a pivotal role in the immune system because they direct the development and activation of CD4(+) T cells. There are three human MHCII isotypes, HLA-DR, HLA-DQ, and HLA-DP. Key transcrip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5dcb78d80ea1e763ca91e5643ae2fc
https://europepmc.org/articles/PMC87290/

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