Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Transcription Factors/*genetics/metabolism"'
Autor:
Luis Lopez-Molina, Anuja Dave, Min Chen, Steven Penfield, Dana R. MacGregor, Naichao Zhang, Mayumi Iwasaki
Publikováno v:
The Plant Journal
Plant Journal, Vol. 98, No 2 (2019) pp. 277-290
Plant Journal, Vol. 98, No 2 (2019) pp. 277-290
Summary Seed dormancy is a widespread and key adaptive trait that is essential for the establishment of soil seed banks and prevention of pre‐harvest sprouting. Herein we demonstrate that the endosperm‐expressed transcription factors ZHOUPI (ZOU)
Autor:
Nico Fischer, Tina Dahlby, Melissa Koomen, Thomas Mandrup-Poulsen, Charna Dibner, Volodymyr Petrenko, Phillip Alexander Keller Andersen, Seyed Mojtaba Ghiasi, Peter Horskjær Rose
Publikováno v:
International Journal of Molecular Sciences
Andersen, P A K, Petrenko, V, Rose, P H, Koomen, M, Fischer, N, Ghiasi, S M, Dahlby, T, Dibner, C & Mandrup-Poulsen, T 2021, ' Proinflammatory cytokines perturb mouse and human pancreatic islet circadian rhythmicity and induce uncoordinated β-cell clock gene expression via nitric oxide, lysine deacetylases, and immunoproteasomal activity ', International Journal of Molecular Sciences, vol. 22, no. 1, 83, pp. 1-25 . https://doi.org/10.3390/ijms22010083
International Journal of Molecular Sciences, Vol. 22, No 1 (2020) P. 83
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 83, p 83 (2021)
Andersen, P A K, Petrenko, V, Rose, P H, Koomen, M, Fischer, N, Ghiasi, S M, Dahlby, T, Dibner, C & Mandrup-Poulsen, T 2021, ' Proinflammatory cytokines perturb mouse and human pancreatic islet circadian rhythmicity and induce uncoordinated β-cell clock gene expression via nitric oxide, lysine deacetylases, and immunoproteasomal activity ', International Journal of Molecular Sciences, vol. 22, no. 1, 83, pp. 1-25 . https://doi.org/10.3390/ijms22010083
International Journal of Molecular Sciences, Vol. 22, No 1 (2020) P. 83
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 83, p 83 (2021)
Pancreatic &beta
cell-specific clock knockout mice develop &beta
cell oxidative-stress and failure, as well as glucose-intolerance. How inflammatory stress affects the cellular clock is under-investigated. Real-time recording of Per2:lucife
cell-specific clock knockout mice develop &beta
cell oxidative-stress and failure, as well as glucose-intolerance. How inflammatory stress affects the cellular clock is under-investigated. Real-time recording of Per2:lucife
Autor:
Antonio Cuadrado, Jürgen Hescheler, Natalia Robledinos-Antón, Karl-Heinz Krause, Eveline Marie Gutzwiller, Vincent Jaquet, Marie José Stasia, Tomo Saric, Marilena Colaianna, Zeynab Nayernia, Elisavet Stathaki, Yousef Hibaoui, Frédérique Sloan-Béna
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 82-93 (2017)
Redox Biology, Vol. 13 (2017) pp. 82-93
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
Redox Biology
Redox Biology, Vol. 13 (2017) pp. 82-93
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
Redox Biology
There is emerging evidence for the involvement of reactive oxygen species (ROS) in the regulation of stem cells and cellular differentiation. Absence of the ROS-generating NADPH oxidase NOX2 in chronic granulomatous disease (CGD) patients, predominan
Autor:
Francesca Frigerio, Søren Fisker Schmidt, Lars la Cour Poulsen, Pierre Maechler, Michael Boergesen, Susanne Mandrup
Publikováno v:
The Journal of biological chemistry
Boergesen, M, Poulsen, L L C, Schmidt, S F, Frigerio, F, Maechler, P & Mandrup, S 2011, ' ChREBP Mediates Glucose Repression of Peroxisome Proliferator-activated Receptor {alpha} Expression in Pancreatic {beta}-Cells ', Journal of Biological Chemistry, vol. 286, no. 15, pp. 13214-13225 . https://doi.org/10.1074/jbc.M110.215467
Journal of Biological Chemistry, Vol. 286, No 15 (2011) pp. 13214-25
Boergesen, M, Poulsen, L L C, Schmidt, S F, Frigerio, F, Maechler, P & Mandrup, S 2011, ' ChREBP Mediates Glucose Repression of Peroxisome Proliferator-activated Receptor {alpha} Expression in Pancreatic {beta}-Cells ', Journal of Biological Chemistry, vol. 286, no. 15, pp. 13214-13225 . https://doi.org/10.1074/jbc.M110.215467
Journal of Biological Chemistry, Vol. 286, No 15 (2011) pp. 13214-25
Chronic exposure to elevated levels of glucose and fatty acids leads to dysfunction of pancreatic β-cells by mechanisms that are only partly understood. The transcription factor peroxisome proliferator-activated receptor α (PPARα) is an important
Autor:
Marc Y. Donath, Anne Wojtusciszyn, Bernhard O. Boehm, Kai Hui Hu He, Kathrin Maedler, Piero Marchetti, Nadine S. Sauter, Roberto Lupi, Benoit R. Gauthier, Thierry Brun
Publikováno v:
BASE-Bielefeld Academic Search Engine
Human molecular genetics, Vol. 17, No 4 (2008) pp. 478-89
Human molecular genetics, Vol. 17, No 4 (2008) pp. 478-89
We previously demonstrated that the transcription factor Pax4 is important for beta-cell replication and survival in rat islets. Herein, we investigate Pax4 expression in islets of non-diabetic and diabetic donors, its regulation by mitogens, glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c9b2c00f8a68d3a9851326c5e5a334
http://doc.rero.ch/record/299485/files/ddm325.pdf
http://doc.rero.ch/record/299485/files/ddm325.pdf
Autor:
Yin, Ruohe
Publikováno v:
Trends in Plant Science, Vol. 22, No 6 (2017) pp. 447-449
PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) is a key transcriptional regulator promoting plant responses to elevated ambient temperatures. A recent study reported that the ultraviolet B radiation (UV-B) photoreceptor UVR8 signaling pathway inhibits PIF4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1400::a7b868ef6ca95b205c91853553ed560e
https://archive-ouverte.unige.ch/unige:103126
https://archive-ouverte.unige.ch/unige:103126
Autor:
Lajos László, Karl-Heinz Krause, Krisztina Pesti, Abinaya Chandrasekaran, Arpad Mike, Phetcharat Phanthong, Julianna Kobolák, Tamás Bellák, Orsolya Biró, Lone N. Rösingh, Vanessa Jane Hall, Narisorn Kitiyanant, Hasan X. Avci, Andras Dinnyes, Kinga Molnár, Annamária Téglási, Anna Ochalek
Publikováno v:
Stem Cell Research, Vol. 25 (2017) pp. 139-151
Stem Cell Research
Chandrasekaran, A, Avci, H, Ochalek, A, Rosingh, L, Molnar, K, Laszlo, L, Bellak, T, Teglasi, A, Pesti, K, Mike, A, Phanthong, P, Biro, O, Hall, V J, Kitiyanant, N, Krause, K-H, Kobolak, J & Dinnyés, A 2017, ' Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells ', Stem Cell Research, vol. 25, pp. 139-151 . https://doi.org/10.1016/j.scr.2017.10.010
Stem Cell Research, Vol 25, Iss C, Pp 139-151 (2017)
Stem Cell Research
Chandrasekaran, A, Avci, H, Ochalek, A, Rosingh, L, Molnar, K, Laszlo, L, Bellak, T, Teglasi, A, Pesti, K, Mike, A, Phanthong, P, Biro, O, Hall, V J, Kitiyanant, N, Krause, K-H, Kobolak, J & Dinnyés, A 2017, ' Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells ', Stem Cell Research, vol. 25, pp. 139-151 . https://doi.org/10.1016/j.scr.2017.10.010
Stem Cell Research, Vol 25, Iss C, Pp 139-151 (2017)
Neural progenitor cells (NPCs) from human induced pluripotent stem cells (hiPSCs) are frequently induced using 3D culture methodologies however, it is unknown whether spheroid-based (3D) neural induction is actually superior to monolayer (2D) neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4125c7cf944c89e664f916809f20bc94
https://archive-ouverte.unige.ch/unige:112338
https://archive-ouverte.unige.ch/unige:112338
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Vol. 45, No 3 (2017) pp. 1186-1199
Nucleic Acids Research, Vol. 45, No 3 (2017) pp. 1186-1199
Acetylation of histones regulates gene expression in eukaryotes. In the yeast Saccharomyces cerevisiae it depends mainly upon the ADA and SAGA histone acetyltransferase complexes for which Gcn5 is the catalytic subunit. Previous screens have determin
Autor:
Caroline Poisson, Mounia Heddad Masson, Jacques Philippe, Yvan Gosmain, Audrey Guérardel, Claire Cheyssac
Publikováno v:
Endocrinology, Vol. 153, No 9 (2012) pp. 4204-15
The Pax6 transcription factor is crucial for pancreatic α-cells. Indeed, Pax6-deficient mouse models are characterized by markedly altered α-cell differentiation. Our objective was to investigate the role of Pax6 in glucagon secretion process. We u
Autor:
Cécile Lebrand, Jozsef Zoltan Kiss, O Riccio, Sahana Murthy, Alexandre Dayer, Gábor Szabó, Laszlo Vutskits, Tania Vitalis
Publikováno v:
Cerebral cortex (New York N.Y. : 1991)
Cerebral Cortex
Cerebral Cortex, vol. 22, no. 1, pp. 86-98
Cerebral Cortex, Vol. 22, No 1 (2012) pp. 86-98
Cerebral Cortex
Cerebral Cortex, vol. 22, no. 1, pp. 86-98
Cerebral Cortex, Vol. 22, No 1 (2012) pp. 86-98
The migration of cortical γ-aminobutyric acidergic interneurons has been extensively studied in rodent embryos, whereas few studies have documented their postnatal migration. Combining in vivo analysis together with time-lapse imaging on cortical sl