Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Trans-synaptic signaling"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
GABAergic interneuron diversity is a key feature in the brain that helps to create different brain activity patterns and behavioral states. Cell type classification schemes—based on anatomical, physiological and molecular features—have provided u
Externí odkaz:
https://doaj.org/article/eb21b792ca6144cdb909aaa766257c64
Autor:
William M. Parkinson, Michelle Dookwah, Mary Lynn Dear, Cheryl L. Gatto, Kazuhiro Aoki, Michael Tiemeyer, Kendal Broadie
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 5, Pp 513-527 (2016)
Congenital disorders of glycosylation (CDGs) constitute a rapidly growing family of human diseases resulting from heritable mutations in genes driving the production and modification of glycoproteins. The resulting symptomatic hypoglycosylation cause
Externí odkaz:
https://doaj.org/article/98b6a7d8a49343b58de1cfca70d9ee51
Publikováno v:
The Journal of Neuroscience
Homeostatic matching of pre- and postsynaptic function has been observed in many species and neural structures, but whether transcriptional changes contribute to this form of trans-synaptic coordination remains unknown. To identify genes whose expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3895e8e2c4b3efc58743b610f94a5450
https://doi.org/10.1523/jneurosci.2979-20.2021
https://doi.org/10.1523/jneurosci.2979-20.2021
Publikováno v:
Neurochemical Research. 47:2591-2601
The mammalian brain contains multiple types of neuronal cells with complex assemblies and distinct structural and functional properties encoded by divergent gene programs. There is increasing evidence that alternative splicing (AS) plays fundamental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a999259ed9ce454e980c2d9db138513c
https://doi.org/10.1007/s11064-021-03384-0
https://doi.org/10.1007/s11064-021-03384-0
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 12, Pp 1365-1378 (2014)
Classic galactosemia (CG) is an autosomal recessive disorder resulting from loss of galactose-1-phosphate uridyltransferase (GALT), which catalyzes conversion of galactose-1-phosphate and uridine diphosphate (UDP)-glucose to glucose-1-phosphate and U
Externí odkaz:
https://doaj.org/article/2a3650bf7249489a891406cedcf8be88
Akademický článek
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Publikováno v:
Neural Development
Neural Development, Vol 15, Iss 1, Pp 1-17 (2020)
Neural Development, Vol 15, Iss 1, Pp 1-17 (2020)
Synapses are the sites of neuron-to-neuron communication and form the basis of the neural circuits that underlie all animal cognition and behavior. Chemical synapses are specialized asymmetric junctions between a presynaptic neuron and a postsynaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3191d98d1e69be3d3e6273c0210e0d
https://doi.org/10.1186/s13064-020-00147-5
https://doi.org/10.1186/s13064-020-00147-5
Publikováno v:
Journal of Cell Science. 133
The exceedingly narrow synaptic cleft (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bf48b9838a145dbf8d29190ed3f1eed
https://doi.org/10.1242/jcs.244186
https://doi.org/10.1242/jcs.244186
Publikováno v:
The Journal of Neuroscience. 38:8388-8406
Excitatory synapses are specialized cell–cell contacts located on actin-rich dendritic spines that mediate information flow and storage in the brain. The postsynaptic adhesion-G protein-coupled receptor (A-GPCR) BAI1 is a critical regulator of exci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbed53df99719811988bfbd4c6d91c2
https://doi.org/10.1523/jneurosci.3461-17.2018
https://doi.org/10.1523/jneurosci.3461-17.2018
Autor:
Guangchen Ji, Ratnamala Pavuluri, Gajanan P. Shelkar, Volker Neugebauer, Jinxu Liu, Sukanya G Gakare, Dinesh Y. Gawande, Shashank M. Dravid, Bishal Misra, Takaki Kiritoshi, Pauravi J. Gandhi
Publikováno v:
Cells
Cells, Vol 10, Iss 2644, p 2644 (2021)
Volume 10
Issue 10
Cells, Vol 10, Iss 2644, p 2644 (2021)
Volume 10
Issue 10
Chronic pain is a debilitating condition involving neuronal dysfunction, but the synaptic mechanisms underlying the persistence of pain are still poorly understood. We found that the synaptic organizer glutamate delta 1 receptor (GluD1) is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c132d756b410ff2d1818eb6bc82eac75
https://doi.org/10.3390/cells10102644
https://doi.org/10.3390/cells10102644