Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Trans-activators/genetics/metabolism"'
Autor:
Rudolf Grosschedl, Duygu Akbas, Dirk Schübeler, Robert Nechanitzky, Rabih Murr, Senthilkumar Ramamoorthy, Sören Boller, Lukas Burger
Publikováno v:
Immunity
Immunity, Vol. 44, No 3 (2016) pp. 527-541
Immunity, Vol. 44, No 3 (2016) pp. 527-541
Lymphopoiesis requires the activation of lineage-specific genes embedded in naive, inaccessible chromatin or in primed, accessible chromatin. The mechanisms responsible for de novo gain of chromatin accessibility, known as "pioneer" function, remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c23e9cb7044ab1cf64d6d8b293541ad
Autor:
Antoinette Monod, Dindo Reyes, Gongyi Zhang, Diego O. Andrey, Ambrose L. Cheung, William L. Kelley
Publikováno v:
Journal of Bacteriology
Journal of Bacteriology, Vol. 193, No 21 (2011) pp. 6020-31
Journal of Bacteriology, Vol. 193, No 21 (2011) pp. 6020-31
The agr locus of Staphylococcus aureus is composed of two divergent transcripts (RNAII and RNAIII) driven by the P2 and P3 promoters. The P2-P3 intergenic region comprises the SarA/SarR binding sites and the four AgrA boxes to which AgrA binds. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d49dbe8f5faa84379a9d055a2471e5
http://jb.asm.org/content/193/21/6020.long
http://jb.asm.org/content/193/21/6020.long
Autor:
Agnieszka Ochoda, Irène Dunn-Siegrist, Geneviève Drifte, Jérôme Pugin, Pierre Tissières, Tanguy Araud
Publikováno v:
Journal of Biological Chemistry, Vol. 284, No 39 (2009) pp. 26261-72
The Journal of biological chemistry
The Journal of biological chemistry
Myeloid differentiation factor 2 (MD-2) binds Gram-negative bacterial lipopolysaccharide with high affinity and is essential for Toll-like receptor 4-dependent signal transduction. MD-2 has recently been recognized as a type II acute phase protein. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4e90364c8c0f1c09418b7dbd591ef3
https://doi.org/10.1074/jbc.m109.042580
https://doi.org/10.1074/jbc.m109.042580
Autor:
William E. Delaney, Christine M. Livingston, Guofeng Cheng, Eduardo Salas, Dhivya Ramakrishnan, Rudolf K. F. Beran, Stephane Daffis, Leanne Peiser, Mei Yu, Hilario Ramos, Li Li, Congrong Niu, Simon P. Fletcher, Dara Burdette, Michel Strubin
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169648 (2017)
PLoS ONE
PLOS ONE, Vol. 12, No 1 (2017) P. e0169648
PLoS ONE
PLOS ONE, Vol. 12, No 1 (2017) P. e0169648
The structural maintenance of chromosome 5/6 complex (Smc5/6) is a restriction factor that represses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing HBV X protein (HBx), which targets Smc5/6 for degradation. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07526c853cf81ca400349bd1786779f4
https://doi.org/10.1371/journal.pone.0169648
https://doi.org/10.1371/journal.pone.0169648
Autor:
Giuseppina Caretti, Fabienne Cocchiarella, Cristina Sidoli, Marie Peretti, Roberto Mantovani, Jean Villard, Walter Reith
Publikováno v:
Journal of Molecular Biology, Vol. 302, No 3 (2000) pp. 539-552
Transcription of major histocompatibility complex (MHC) class II genes depends upon the trimeric complexes RFX and NF-Y binding to the conserved X-Y promoter elements. We produced and purified the RFX subunits from Escherichia coli, reconstituted DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d952dd8593f29f0a8c869e2c44b769
https://doi.org/10.1006/jmbi.2000.4028
https://doi.org/10.1006/jmbi.2000.4028
Autor:
Mark A. Magnuson, Weiping Yuan, Klaus H. Kaestner, Brandon L. Taylor, Jacqueline R. Benthuysen, Catherine Lee May, Pedro Luis Herrera, Fabrizio Thorel, Jingxuan Liu, Ashleigh E. Schaffer, Yang Jiao, Maike Sander
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003274 (2013)
PLoS Genetics
PLOS Genetics, Vol. 9, No 1 (2013) P. e1003274
PLoS Genetics
PLOS Genetics, Vol. 9, No 1 (2013) P. e1003274
All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f76441d64224df86e7ff6a7ed2b329f
http://europepmc.org/articles/PMC3561089?pdf=render
http://europepmc.org/articles/PMC3561089?pdf=render
Autor:
Yvan Gosmain, Jacques Philippe, Caroline Poisson, Liora S. Katz, Mounia Heddad Masson, Claire Cheyssac
Publikováno v:
Molecular Endocrinology, Vol. 26, No 4 (2012) pp. 696-709
The Pax6 transcription factor is crucial for endocrine cell differentiation and function. Indeed, mutations of Pax6 are associated with a diabetic phenotype and a drastic decrease of insulin-positive cell number. Our aim was to better define the β-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a58cb8bdd3e490d75964eb100b2896a
https://archive-ouverte.unige.ch/unige:31925
https://archive-ouverte.unige.ch/unige:31925
Publikováno v:
Journal of Biological Chemistry, Vol. 286, No 8 (2011) pp. 6049-60
Resveratrol, a polyphenol compound, is known for its effects on energy homeostasis. With properties of energy sensors mediating effects of calorie restriction, sirtuins are targets of resveratrol. The mammalian sirtuin homolog SIRT1 is a protein deac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93cfd497823e39ed4b2f2f39a3347cf2
https://archive-ouverte.unige.ch/unige:25240
https://archive-ouverte.unige.ch/unige:25240
Publikováno v:
Genes and Development, Vol. 25, No 16 (2011) pp. 1680-5
Using single transcription factors to reprogram cells could produce important insights into the epigenetic mechanisms that direct normal differentiation, or counter inappropriate plasticity, or even provide new ways of manipulating normal ontogeny in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64b7ac8a429b42abce7f2ad243b4a2d
https://archive-ouverte.unige.ch/unige:25633
https://archive-ouverte.unige.ch/unige:25633
Autor:
Tzika, A. A., Astrakas, L. G., Cao, H., Mintzopoulos, D., Zhang, Q., Padfield, K., Yu, H., Mindrinos, M. N., Rahme, L. G., Tompkins, R. G.
It has been suggested that intramyocellular lipids (IMCLs) may serve as biomarkers of insulin resistance and mitochondrial dysfunction. Using a hind-limb mouse model of burn trauma, we tested the hypothesis that severe localized burn trauma involving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::4f89d2c4993e7242bbc5b56eaffae551
http://olympias.lib.uoi.gr/jspui/handle/123456789/19849
http://olympias.lib.uoi.gr/jspui/handle/123456789/19849