Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Trans-Activators/metabolism"'
Autor:
Yu Ting Ong, Jorge Andrade, Max Armbruster, Chenyue Shi, Marco Castro, Ana S. H. Costa, Toshiya Sugino, Guy Eelen, Barbara Zimmermann, Kerstin Wilhelm, Joseph Lim, Shuichi Watanabe, Stefan Guenther, Andre Schneider, Francesca Zanconato, Manuel Kaulich, Duojia Pan, Thomas Braun, Holger Gerhardt, Alejo Efeyan, Peter Carmeliet, Stefano Piccolo, Ana Rita Grosso, Michael Potente
Publikováno v:
Nature Metabolism
Funding Information: The research in the M.P. laboratory was supported by the Max Planck Society, the European Research Council (ERC) Consolidator Grant EMERGE (no. 773047), the Deutsche Forschungsgemeinschaft (DFG, Project-ID 75732319 – SFB 834),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949e298d1cb95c83b830f240881e3703
https://doi.org/10.1038/s42255-022-00584-y
https://doi.org/10.1038/s42255-022-00584-y
Autor:
Liu, B., Liu, Y. F., Du, Y. R., Mardaryev, A. N., Yang, W., Chen, H., Xu, Z. M., Xu, C. Q., Zhang, X. R., Botchkarev, V. A., Zhang, Y., Xu, G. L.
Thymic epithelial cells (TECs) are the main component of the thymic stroma, which supports T-cell proliferation and repertoire selection. Here, we demonstrate that Cbx4, a Polycomb protein that is highly expressed in the thymic epithelium, has an ess
Externí odkaz:
http://hdl.handle.net/10454/6068
Autor:
Ariane Rochat, Thimios A. Mitsiadis, Yann Barrandon, Hideo Oshima, Christèle Gonneau, Michael Nicolas, Jun-ichi Sakabe, Stéphanie Claudinot, Paola Bonfanti, Daniel Littman, Geert A. Martens
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature communications, vol. 11, no. 1, pp. 5645
Nature Communications
Nature communications, vol. 11, no. 1, pp. 5645
The formation of hair follicles, a landmark of mammals, requires complex mesenchymal–epithelial interactions and it is commonly believed that embryonic epidermal cells are the only cells that can respond to hair follicle morphogenetic signals in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425cf172c4b9191d9b55357e76f8f50e
https://doi.org/10.1038/s41467-020-19485-3
https://doi.org/10.1038/s41467-020-19485-3
Autor:
Michel Strubin, Rudolf K. F. Beran, Laetitia Gerossier, Simon P. Fletcher, Christine M. Livingston, Fabien Abdul, Pieter C van Breugel, Henrik Mueller, Congrong Niu, Adrien Decorsiere, Olivier Hantz
Publikováno v:
Nature
Nature, Vol. 531, No 7594 (2016) pp. 386-389
Nature, Nature Publishing Group, 2016, 531 (7594), pp.386-389. ⟨10.1038/nature17170⟩
Nature, Vol. 531, No 7594 (2016) pp. 386-389
Nature, Nature Publishing Group, 2016, 531 (7594), pp.386-389. ⟨10.1038/nature17170⟩
Chronic hepatitis B virus infection is a leading cause of cirrhosis and liver cancer. Hepatitis B virus encodes the regulatory HBx protein whose primary role is to promote transcription of the viral genome, which persists as an extrachromosomal DNA c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64462e2ec856d32508eaa7900d6ba34d
http://archive-ouverte.unige.ch/unige:85682
http://archive-ouverte.unige.ch/unige:85682
Autor:
Galvan, Laurie, Francelle, Laetitia, Gaillard, Marie-Claude, De Longprez, Lucie, Carrillo-de Sauvage, Maria-Angeles, Liot, Géraldine, Cambon, Karine, Stimmer, Lev, Luccantoni, Sophie, Flament, Julien, Valette, Julien, De Chaldée, Michel, Auregan, Gwenaëlle, Guillermier, Martine, Joséphine, Charlène, Petit, Fanny, Jan, Caroline, Jarrige, Margot, Dufour, Noëlle, Bonvento, Gilles, Humbert, Sandrine, Saudou, Frédéric, Hantraye, Philippe, Mérienne, Karine, Bemelmans, Alexis-Pierre, Perrier, Anselme, Déglon, Nicole, Brouillet, Emmanuel
Publikováno v:
Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain-A Journal of Neurology, 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain
Brain, vol. 141, no. 5, pp. 1434-1454
Brain-A Journal of Neurology, Oxford University Press (OUP), 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain-A Journal of Neurology, 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain
Brain, vol. 141, no. 5, pp. 1434-1454
Expression of the neuronal kinase DCLK3 is reduced in Huntington’s disease. Galvan et al. report that DCLK3 silencing in the mouse striatum exacerbates the toxicity of mutant huntingtin, whereas DCLK3 overexpression is neuroprotective, and show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eb0c82958019d7f33356d092f6de6863
https://hal.archives-ouvertes.fr/hal-02459743
https://hal.archives-ouvertes.fr/hal-02459743
Autor:
Alexia Paturel, Fabien Filleton, Laetitia Gerossier, Janet E. Hall, Fabien Abdul, Lucie Etienne, Michel Strubin
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2018, 92 (16), ⟨10.1128/JVI.00769-18⟩
Journal of Virology, 2018, 92 (16), ⟨10.1128/JVI.00769-18⟩
Journal of Virology, Vol. 92, No 16 (2018) pp. e00769-18
Journal of Virology, American Society for Microbiology, 2018, 92 (16), ⟨10.1128/JVI.00769-18⟩
Journal of Virology, 2018, 92 (16), ⟨10.1128/JVI.00769-18⟩
Journal of Virology, Vol. 92, No 16 (2018) pp. e00769-18
International audience; Chronic infection with hepatitis B virus (HBV) is a major cause of liver disease and cancer in humans. HBVs (family Hepadnaviridae) have been associated with mammals for millions of years. Recently, the Smc5/6 complex, known f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1225137b99535bc394d05ba2e9ea7bc
https://hal.archives-ouvertes.fr/hal-01911198
https://hal.archives-ouvertes.fr/hal-01911198
Autor:
Yung Hae Kim, Jacques-Antoine Haefliger, Chai An Mao, Anne Grapin-Botton, David Martin, Dror Sever
Publikováno v:
Developmental Biology, vol. 405, no. 2, pp. 316-327
Developmental biology
Developmental biology
To contribute to devise successful beta-cell differentiation strategies for the cure of Type 1 diabetes we sought to uncover barriers that restrict endocrine fate acquisition by studying the role of the transcriptional repressor REST in the developin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b56bf5e0c72b260fda4d146f46f850
Autor:
Mohcine Elmessaoudi-Idrissi, Arnaud Blondel, Anass Kettani, Marc P. Windisch, Sayeh Ezzikouri, Soumaya Benjelloun
Publikováno v:
Current Medicinal Chemistry
Current Medicinal Chemistry, Bentham Science Publishers, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, Bentham Science Publishers, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Hepatitis B Virus (HBV) is a major global health burden. Interferon alpha and nucleos(t)ide analogues are currently the standard-of-care for chronic HBV infection. However, these antiviral agents have limited efficacy and do not result in a sustained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5619f110d1c8caa76ef3dfca0e7a17e0
https://pubmed.ncbi.nlm.nih.gov/29473495
https://pubmed.ncbi.nlm.nih.gov/29473495
Autor:
François Mach, Roberta Sanguineti, Alessandra Puddu, Giorgio Luciano Viviani, Fabrizio Montecucco, Alessio Nencioni, Arianna Durante
Publikováno v:
Mediators of Inflammation, Vol. 2013 (2013) P. 317120
Mediators of Inflammation
Mediators of Inflammation, Vol 2013 (2013)
Mediators of Inflammation
Mediators of Inflammation, Vol 2013 (2013)
Advanced glycation end products (AGEs) might play a pathophysiological role in the development of diabetes and its complications. AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e81936c2739939c2843eb8a253f1e9
https://doi.org/10.1155/2013/317120
https://doi.org/10.1155/2013/317120
Autor:
Joy L. Nishikawa, Dominique Sanglard, Anders M. Näär, Riccardo Torelli, Luís A. Vale-Silva, Maurizio Sanguinetti, Brunella Posteraro, Haribabu Arthanari, Andras Boeszoermenyi, Ruslan I. Sadreyev, Jayaram Bhyravabhotla, Goutam Dev Mukherjee, Gerhard Wagner, Fei Ji, Sara J. Buhrlage, Nathanael S. Gray, Yoo-Jin Sohn, Vladimir Gelev
Publikováno v:
Nature
Europe PubMed Central
Nature, vol. 530, no. 7591, pp. 485-489
Europe PubMed Central
Nature, vol. 530, no. 7591, pp. 485-489
Eukaryotic transcription activators stimulate the expression of specific sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting Mediator complex. Aberrant function of transcription activators has been impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387b05bb85fa8b6fb9b167c377f136ee
http://hdl.handle.net/10807/72311
http://hdl.handle.net/10807/72311