Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Trang T.T. Nguyen"'
Autor:
Trang T.T. Nguyen, M. Hojny
Publikováno v:
Archives of Foundry Engineering, Vol vol. 22, Iss No 3, Pp 67-80 (2022)
Smoothed Particle Hydrodynamics (SPH) is a Lagrangian formula-based non-grid computational method for simulating fluid flows, solid deformation, and fluid structured systems. SPH is a method widely applied in many fields of science and engineering, e
Externí odkaz:
https://doaj.org/article/e3baf17117414b1ba4da2aedcdedd22c
Autor:
Markus D. Siegelin, Peter Canoll, Jeffrey N. Bruce, Georg Karpel-Massler, Catarina M. Quinzii, Mike-Andrew Westhoff, Elena Bianchetti, Giulio Kleiner, Maria J. Sanchez-Quintero, Consuelo Torrini, Chang Shu, Junfei Zhao, Aayushi Mahajan, Nelson Humala, Angeliki Mela, Enyuan Shang, Trang T.T. Nguyen, Yiru Zhang
Figure S1. Crizotinib resistant cells reveal a reprogrammed tumor metabolism. Figure S2. Crizotinib modulates fatty acid metabolism and mitochondrial parameters. Figure S3. Tracing analysis reveals distinct modulation of metabolism by MET inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3ca270b2531ae2a9908279f0411cd4
https://doi.org/10.1158/0008-5472.22423917.v1
https://doi.org/10.1158/0008-5472.22423917.v1
Autor:
Markus D. Siegelin, Joshua E. Allen, Varun V. Prabhu, Georg Karpel-Massler, Mike-Andrew Westhoff, Catarina M. Quinzii, Maria J. Sanchez-Quintero, Giulio Kleiner, Trang T.T. Nguyen, Chang Shu, Elena Bianchetti, Yiru Zhang, Chiaki T. Ishida
Purpose: The goal of this study is to enhance the efficacy of imipridones, a novel class of AKT/ERK inhibitors that displayed limited therapeutic efficacy against glioblastoma (GBM).Experimental Design: Gene set enrichment, LC/MS, and extracellular f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a1bacae2ecb3e358c90ecca13396b5
https://doi.org/10.1158/1078-0432.c.6529275.v1
https://doi.org/10.1158/1078-0432.c.6529275.v1
Autor:
Markus D. Siegelin, Georg Karpel-Massler, Mike-Andrew Westhoff, Joshua E. Allen, Varun V. Prabhu, Hasan Orhan Akman, Chang Shu, Consuelo Torrini, Salveena Schiffgens, Enyuan Shang, Trang T.T. Nguyen
Supplementary Data from Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab5484a8c37e8dc01f67fc65c6d43ca
https://doi.org/10.1158/1078-0432.22482102.v1
https://doi.org/10.1158/1078-0432.22482102.v1
Autor:
Markus D. Siegelin, Peter Canoll, Jeffrey N. Bruce, Georg Karpel-Massler, Catarina M. Quinzii, Mike-Andrew Westhoff, Elena Bianchetti, Giulio Kleiner, Maria J. Sanchez-Quintero, Consuelo Torrini, Chang Shu, Junfei Zhao, Aayushi Mahajan, Nelson Humala, Angeliki Mela, Enyuan Shang, Trang T.T. Nguyen, Yiru Zhang
The receptor kinase c-MET has emerged as a target for glioblastoma therapy. However, treatment resistance emerges inevitably. Here, we performed global metabolite screening with metabolite set enrichment coupled with transcriptome and gene set enrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6927c0d5296b85502a38feeb20f8211
https://doi.org/10.1158/0008-5472.c.6511608.v1
https://doi.org/10.1158/0008-5472.c.6511608.v1
Autor:
Markus D. Siegelin, Joshua E. Allen, Varun V. Prabhu, Georg Karpel-Massler, Mike-Andrew Westhoff, Catarina M. Quinzii, Maria J. Sanchez-Quintero, Giulio Kleiner, Trang T.T. Nguyen, Chang Shu, Elena Bianchetti, Yiru Zhang, Chiaki T. Ishida
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5a9bcbb49c9b971f9059198bda4d09
https://doi.org/10.1158/1078-0432.22476039
https://doi.org/10.1158/1078-0432.22476039
Autor:
Markus D. Siegelin, Georg Karpel-Massler, Mike-Andrew Westhoff, Joshua E. Allen, Varun V. Prabhu, Hasan Orhan Akman, Chang Shu, Consuelo Torrini, Salveena Schiffgens, Enyuan Shang, Trang T.T. Nguyen
Purpose:Novel therapeutic targets are critical to unravel for the most common primary brain tumor in adults, glioblastoma (GBM). We have identified a novel synthetic lethal interaction between ClpP activation and HDAC1/2 inhibition that converges on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3b6c6a44a2c49842334d5fe11b40b9
https://doi.org/10.1158/1078-0432.c.6530823
https://doi.org/10.1158/1078-0432.c.6530823
Autor:
Markus D. Siegelin, Joshua E. Allen, Varun V. Prabhu, Georg Karpel-Massler, Mike-Andrew Westhoff, Catarina M. Quinzii, Maria J. Sanchez-Quintero, Giulio Kleiner, Trang T.T. Nguyen, Chang Shu, Elena Bianchetti, Yiru Zhang, Chiaki T. Ishida
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bee458ece33afb8bfc8c05e0978f484
https://doi.org/10.1158/1078-0432.22476045.v1
https://doi.org/10.1158/1078-0432.22476045.v1
Autor:
Markus D. Siegelin, Joshua E. Allen, Varun V. Prabhu, Georg Karpel-Massler, Mike-Andrew Westhoff, Catarina M. Quinzii, Maria J. Sanchez-Quintero, Giulio Kleiner, Trang T.T. Nguyen, Chang Shu, Elena Bianchetti, Yiru Zhang, Chiaki T. Ishida
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8b622d645b50d7c95cba899fb8e671
https://doi.org/10.1158/1078-0432.22476042.v1
https://doi.org/10.1158/1078-0432.22476042.v1
Autor:
Kyung Min Chung, Hyunha Kim, Cláudio Gouveia Roque, Ethan P. McCurdy, Trang T.T. Nguyen, Markus D. Siegelin, Jee-Yeon Hwang, Ulrich Hengst
Publikováno v:
Cell reports. 41(3)
Cells possess several conserved adaptive mechanisms to respond to stress. Stress signaling is initiated to reestablish cellular homeostasis, but its effects on the tissue or systemic levels are far less understood. We report that the secreted luminal