Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Trang M. Tran"'
Autor:
Alethea B. Tabor, Fiona Bellany, Trang M. Tran, Helen Allan, Ivan Gout, A. W. Edith Chan, Yugo Tsuchiya
Publikováno v:
Bioorganic & Medicinal Chemistry. 40:116106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1ebb4e224fad319d68939fa3f0123bd
https://doi.org/10.1016/j.bmc.2021.116106
https://doi.org/10.1016/j.bmc.2021.116106
Autor:
Trang M. Tran, A. W. Edith Chan, Alethea B. Tabor, Ivan Gout, Helen Allan, Yugo Tsuchiya, Fiona Bellany
Publikováno v:
Bioorg Med Chem
Coenzyme A (CoA) is a highly selective inhibitor of the mitotic regulatory enzyme Aurora A kinase, with a novel mode of action. Herein we report the design and synthesis of analogues of CoA as inhibitors of Aurora A kinase. We have designed and synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9e960c67af80823182bc8deb19cb6c
https://doi.org/10.1016/j.bmc.2020.115740
https://doi.org/10.1016/j.bmc.2020.115740
Autor:
Bess Yi Kun Yu, Alexander Zhyvoloup, Richard Bayliss, Mark Skehel, John L. Carroll, Trang M. Tran, Claire E. Eyers, Yugo Tsuchiya, Samantha Ferries, Ivan Gout, Fiona Bellany, Jovana Baković, Valeriy Filonenko, Selena G. Burgess, Lalitha Guruprasad, Yueyang Huang, Aw Edith Chan, Sew Y. Peak-Chew, Jenny Bormann, Matthias Vonderach, Oleg Garifulin, Alethea B. Tabor, Patrick A. Eyers, Dominic P. Byrne
Publikováno v:
Redox Biology
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology, Vol 28, Iss, Pp-(2020)
Aurora A kinase is a master mitotic regulator whose functions are controlled by several regulatory interactions and post-translational modifications. It is frequently dysregulated in cancer, making Aurora A inhibition a very attractive antitumor targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c870c2e91d80ca1c1f6f8af1beb10abe
https://doi.org/10.1016/j.redox.2019.101318
https://doi.org/10.1016/j.redox.2019.101318
Autor:
Alethea B. Tabor, Valeriy Filonenko, Yueyan Huang, Patrick A. Eyers, Jenny Bormann, Oleg Garifulin, Claire E. Eyers, Selena G. Burgess, Yugo Tsuchiya, Richard Bayliss, Fiona Bellany, Alexander Zhyvoloup, John L. Carroll, Trang M. Tran, Sew Y. Peak-Chew, Samantha Ferries, Jovana Baković, Mark Skehel, Ivan Gout, Lalitha Guruprasad, Dominic P. Byrne, Aw Edith Chan
SummaryAurora A is a cell cycle protein kinase implicated in multiple human cancers, and several Aurora A-specific kinase inhibitors have progressed into clinical trials. In this study, we report structural and cellular analysis of a novel biochemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f59ea812a860b16428ca8c6587b969
Autor:
Stefano Ongarello, Jennifer Cohn, Trang M. Tran, Laura F. White, Claudia M. Denkinger, Philippa Easterbrook, Samuel G Schumacher, J. Morgan Freiman, Benjamin P. Linas
Background Diagnosis of chronic hepatitis C virus (HCV) infection requires both a positive HCV antibody screen and confirmatory nucleic acid testing (NAT). Testing for hepatitis C virus core antigen (HCVcAg) is a potential alternative to NAT. Purpose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c683c334825da0849cd637bd34aa003d
https://europepmc.org/articles/PMC5345254/
https://europepmc.org/articles/PMC5345254/
Publikováno v:
The lancet. HIV. 3(10)
Summary Background Many HIV-positive children in low-income and middle-income countries remain undiagnosed. Although HIV testing in children at health facilities is recommended by WHO, it is not well implemented. This systematic review and meta-analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d61e1e560737728c879490a5495120b
https://pubmed.ncbi.nlm.nih.gov/27658877
https://pubmed.ncbi.nlm.nih.gov/27658877
Autor:
Eleni, Pontiki, Dimitra, Hadjipavlou-Litina, Alexandros, Patsilinakos, Trang M, Tran, Charles M, Marson
Publikováno v:
Future medicinal chemistry
Background Reactive oxygen species are associated with inflammation implicated in cancer, atherosclerosis and autoimmune diseases. The complex nature of inflammation and of oxidative stress suggests that dual-target agents may be effective in combati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8b580d19df5f26b2214308db09ebd9a3
http://hdl.handle.net/11573/1019033
http://hdl.handle.net/11573/1019033
Autor:
Sushanta K. Banerjee, Robert S. Richards, Prateek Sharma, Trang M Tran, Allan P. Weston, Rachel Cherian
Publikováno v:
American Journal of Gastroenterology. 96:1355-1362
OBJECTIVES: The presence of low grade dysplasia (LGD) within Barrett’s esophagus (BE) has a multitude of ramifications. Identification of markers that could risk stratify LGD would be of great clinical benefit. We aimed to prospectively evaluate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a289340884efff8008c60b15e6ec18b
https://doi.org/10.1111/j.1572-0241.2001.03851.x
https://doi.org/10.1111/j.1572-0241.2001.03851.x
Autor:
Lourdes Castañeda, James R. Baker, Vijay Chudasama, Elizabeth A. Hull, Richard J. Fitzmaurice, Antoine Maruani, João P. Nunes, Cristina Marculescu, Mark E. B. Smith, Trang M. Tran, Zoë V. F. Wright, Stephen Caddick, Lyn H. Jones
Publikováno v:
Tetrahedron Letters
Graphical abstract
Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability
Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f2f4c810d38c5edaed3bd0ca177f80
https://pubmed.ncbi.nlm.nih.gov/24058217
https://pubmed.ncbi.nlm.nih.gov/24058217