Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Trang Huyen Lai"'
Publikováno v:
Adipocyte, Vol 13, Iss 1 (2024)
ABSTRACTAdipogenic differentiation and thermogenesis in brown adipose tissue (BAT) undergo dynamic processes, altering phenotypes and gene expressions. Proper reference genes in gene expression analysis are crucial to mitigate experimental variances
Externí odkaz:
https://doaj.org/article/e1ad14a139b8490681d625b37b8da2f7
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 759 (2024)
Delphinidin (Delp), a natural antioxidant, has shown promise in treating age-related ailments such as osteoarthritis (OA). This study investigates the impact of delphinidin on intervertebral disc degeneration (IVDD) using human nucleus pulposus cells
Externí odkaz:
https://doaj.org/article/128b945d12c94f49814e7c7b6c4f9c7f
Autor:
Trang Minh Pham, Mahmoud Ahmed, Trang Huyen Lai, Md Entaz Bahar, Jin Seok Hwang, Rizi Firman Maulidi, Quang Nhat Ngo, Deok Ryong Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2956 (2024)
BCR-ABL tyrosine kinase inhibitors are commonly employed for the treatment of chronic myeloid leukemia, yet their impact on human malignant melanoma remains uncertain. In this study, we delved into the underlying mechanisms of specific BCR-ABL tyrosi
Externí odkaz:
https://doaj.org/article/cb6ffd25c0c74a0fb42ba0499130aa8f
Autor:
Trang Huyen Lai, Mahmoud Ahmed, Jin Seok Hwang, Md Entaz Bahar, Trang Minh Pham, Jinsung Yang, Wanil Kim, Rizi Firman Maulidi, Dong-Kun Lee, Dong-Hee Kim, Hyun Joon Kim, Deok Ryong Kim
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Breast cancer is a common tumor type among women, with a high fatality due to metastasis. Metastasis suppressors encode proteins that inhibit the metastatic cascade independent of the primary tumor growth. Raf kinase inhibitory protein (RKIP) is one
Externí odkaz:
https://doaj.org/article/687edc80686e48f28398be70a04b20f8
Autor:
Sahib Zada, Jin Seok Hwang, Trang Huyen Lai, Trang Minh Pham, Mahmoud Ahmed, Omar Elashkar, Wanil Kim, Deok Ryong Kim
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Backgound Autophagy controls levels of cellular components during normal and stress conditions; thus, it is a pivotal process for the maintenance of cell homeostasis. In cancer, autophagy protects cells from cancerous transformations that ca
Externí odkaz:
https://doaj.org/article/de8d55ba3838421799470c7947d6a68f
Autor:
Mahmoud Ahmed, Trang Huyen Lai, Trang Minh Pham, Sahib Zada, Omar Elashkar, Jin Seok Hwang, Deok Ryong Kim
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
We previously showed that some adipogenic transcription factors such as CEBPB and PPARG directly and indirectly regulate autophagy gene expression in adipogenesis. The order and effect of these events are undetermined. In this study, we modeled the g
Externí odkaz:
https://doaj.org/article/cc5f4327f2a045f09749ab449a0bc3dd
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Differentiating 3T3-L1 pre-adipocytes are a mixture of non-identical culture cells. It is vital to identify the cell types that respond to the induction stimulus to understand the pre-adipocyte potential and the mature adipocyte behavior. To test thi
Externí odkaz:
https://doaj.org/article/8ce2093c1010468f8e91a633d9eacf71
Autor:
Jin Seok Hwang, Trang Huyen Lai, Mahmoud Ahmed, Trang Minh Pham, Omar Elashkar, Entaz Bahar, Deok Ryong Kim
Publikováno v:
Cancers, Vol 14, Iss 19, p 4845 (2022)
Metastasis is associated with poor prognosis and is the major cause of death in cancer patients. The epithelial to mesenchymal transition (EMT) is essential for cancer cells to acquire a highly migratory phenotype. Metabolic reprogramming is required
Externí odkaz:
https://doaj.org/article/2a8d2ca0b1ec44099029d9a84c082d87
Autor:
Md Entaz Bahar, Jin Seok Hwang, Mahmoud Ahmed, Trang Huyen Lai, Trang Minh Pham, Omar Elashkar, Kazi-Marjahan Akter, Dong-Hee Kim, Jinsung Yang, Deok Ryong Kim
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1571 (2022)
Intervertebral disc degeneration (IVDD) is a prevalent cause of low back pain. IVDD is characterized by abnormal expression of extracellular matrix components such as collagen and aggrecan. In addition, it results in dysfunctional growth, senescence,
Externí odkaz:
https://doaj.org/article/8ad337ad6c3a4f78abf6b6e8eedb2c76
Publikováno v:
Cancers, Vol 13, Iss 23, p 6098 (2021)
Drug screening strategies focus on quantifying the phenotypic effects of different compounds on biological systems. High-throughput technologies have the potential to understand further the mechanisms by which these drugs produce the desired outcome.
Externí odkaz:
https://doaj.org/article/91729af46cc642cb99532d54fcfae443