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Direct and quantitative evaluation of the major human CYP contribution (fmCYP) to drug clearance using the in vitro Silensomes™ model.

Autor: Parmentier Y; a Department of Biopharmaceutical Research , Technologie Servier , Orléans Cedex , France., Pothier C; a Department of Biopharmaceutical Research , Technologie Servier , Orléans Cedex , France., Hewitt N; b Scientific Writing Services , Erzhausen , Germany., Vincent L; a Department of Biopharmaceutical Research , Technologie Servier , Orléans Cedex , France., Caradec F; a Department of Biopharmaceutical Research , Technologie Servier , Orléans Cedex , France., Liu J; c SIMM-SERVIER Joint Biopharmacy Laboratory, Shanghai Institute of Materia Medica , Shanghai , China., Lin F; c SIMM-SERVIER Joint Biopharmacy Laboratory, Shanghai Institute of Materia Medica , Shanghai , China., Trancart MM; d Eurosafe , Saint-Grégoire , France , and., Guillet F; d Eurosafe , Saint-Grégoire , France , and., Bouaita B; e Biopredic International , Rennes , France., Chesne C; e Biopredic International , Rennes , France., Walther B; a Department of Biopharmaceutical Research , Technologie Servier , Orléans Cedex , France.

Publikováno v: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2019 Jan; Vol. 49 (1), pp. 22-35. Date of Electronic Publication: 2018 Jan 10.

Effect of cryopreservation on the activity of OATP1B1/3 and OCT1 in isolated human hepatocytes.

Autor: Badolo L; Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark. laba@lundbeck.com, Trancart MM, Gustavsson L, Chesné C

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2011 Apr 25; Vol. 190 (2-3), pp. 165-70. Date of Electronic Publication: 2011 Feb 26.