Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tran Khac Dien"'
Autor:
Peter J. Vries, Nguyen Xuan Khanh, Tran Khac Dien, Le Nguyen Binh, Nguyen Thi Yen, Dao Dinh Due, Chris J. Boxtel, Piet A. Kager, Bob Berg, Jan Butter, Bui Hien, R. Koopman, Els Portier, Pham Song, Nguyen Cam Thach
Publikováno v:
Tropical Medicine & International Health. 2:957-962
Artemisinin is mainly eliminated by hepatic transformation. To investigate whether the clearance of artemisinin in patients with liver cirrhosis is different from healthy volunteers, a pharmacokinetic study was performed in male Vietnamese patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68db57c3488e5bcaeb30b0bf279dcb4f
https://doi.org/10.1046/j.1365-3156.1997.d01-155.x
https://doi.org/10.1046/j.1365-3156.1997.d01-155.x
Autor:
C. J. Van Boxtel, Piet A. Kager, P. J. de Vries, Dao Dinh Duc, Richard P. Koopmans, Tran Khac Dien, Nguyen Xuan Khanh, Le Nguyen Binh
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:1069-1072
The influence of food intake on the pharmacokinetics of artemisinin was studied with six healthy Vietnamese male subjects. In a crossover study, artemisinin capsules (500 mg) were administered with and without food after an overnight fast. Plasma sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372d285f12e3108b35f646c43e077497
https://doi.org/10.1128/aac.41.5.1069
https://doi.org/10.1128/aac.41.5.1069
Autor:
Chris J. van Boxtel, Piet A. Kager, Tran Khac Dien, Peter J. de Vries, Nguyen Xuan Khanh, Dao Dinh Duc, Richard P. Koopmans
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene, 92(4), 434-436. Elsevier
Eight male Vietnamese malaria patients received 600 mg of artemisinin in a single dose of 3 suppositories containing 200 mg each; 24 h later they received a single oral dose of mefloquine, 15 mg/kg. Plasma artemisinin concentrations were measured unt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf27322e9058680918e3abf12f7202a
https://doi.org/10.1016/s0035-9203(98)91082-3
https://doi.org/10.1016/s0035-9203(98)91082-3
Autor:
Piet A. Kager, Dao Dinh Duc, C. J. Van Boxtel, Le Dang Ha, Tran Khac Dien, P. J. de Vries, Nguyen Xuan Khanh, Richard P. Koopmans
Publikováno v:
The American journal of tropical medicine and hygiene. 60(2)
Eight healthy Vietnamese male subjects received 400 mg artemisinin formulated into fatty suppositories (FS), and six different subjects received 500 mg of artemisinin formulated in polyethylene glycol suppositories (PEGS). Plasma concentrations were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a1c97facf054db45173675f5192c09
https://pubmed.ncbi.nlm.nih.gov/10072143
https://pubmed.ncbi.nlm.nih.gov/10072143
Autor:
Tran Khac Dien, C. A. A. Van Der Graaf, C. J. van Boxtel, M. A. van Agtmael, Richard P. Koopmans
Publikováno v:
Van Agtmael, M A, Van der Graaf, C A A, Dien, T K, Koopmans, R P & Van Boxtel, C J 1998, ' The contribution of the enzymes CYP2D6 and CYP2C19 in the demethylation of artemether in healthy subjects ', European Journal of Drug Metabolism and Pharmacokinetics, vol. 23, no. 3, pp. 429-436 . https://doi.org/10.1007/BF03192305
European Journal of Drug Metabolism and Pharmacokinetics, 23(3), 429-436. Springer Paris
European Journal of Drug Metabolism and Pharmacokinetics, 23(3), 429-436. Springer Paris
The contribution of the enzymes CYP2D6 and CYP2C19 to the metabolism of artemether was evaluated in a cross-over study in seven healthy adult Caucasian subjects. The pharmacokinetic properties of artemether and its active metabolite dihydroartemisini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea2c901d193f7a713504b4689faf917
https://pubmed.ncbi.nlm.nih.gov/9842988
https://pubmed.ncbi.nlm.nih.gov/9842988