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The Structure and Function of the Bacterial Osmotically Inducible Protein Y.

Autor: Iyer A; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands. Electronic address: a.s.iyer@rug.nl., Frallicciardi J; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., le Paige UBA; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands., Narasimhan S; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands., Luo Y; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands., Sieiro PA; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., Syga L; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., van den Brekel F; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., Tran BM; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., Tjioe R; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., Schuurman-Wolters G; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., Stuart MCA; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands., Baldus M; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands., van Ingen H; NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands. Electronic address: h.vaningen@uu.nl., Poolman B; Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands. Electronic address: b.poolman@rug.nl.

Publikováno v: Journal of molecular biology [J Mol Biol] 2024 Aug 15; Vol. 436 (16), pp. 168668. Date of Electronic Publication: 2024 Jun 20.

Renin-Angiotensin Inhibitor, Captopril, Attenuates Growth of Patient-Derived Colorectal Liver Metastasis Organoids.

Autor: Riddiough GE; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Lance Townsend Building, Level 8, 145 Studley Road, Heidelberg, VIC 3084, Australia.; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute, Melbourne, VIC 3000, Australia., Fifis T; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Lance Townsend Building, Level 8, 145 Studley Road, Heidelberg, VIC 3084, Australia., Muralidharan V; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Lance Townsend Building, Level 8, 145 Studley Road, Heidelberg, VIC 3084, Australia., Christophi C; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Lance Townsend Building, Level 8, 145 Studley Road, Heidelberg, VIC 3084, Australia., Tran BM; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute, Melbourne, VIC 3000, Australia., Perini MV; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Lance Townsend Building, Level 8, 145 Studley Road, Heidelberg, VIC 3084, Australia., Vincan E; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute, Melbourne, VIC 3000, Australia.; Victorian Infectious Diseases Reference Laboratory, The Peter Doherty Institute, Melbourne, VIC 3000, Australia.; Curtin Medical School, Curtin University, Perth, WA 6102, Australia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 14; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 14.

Assessment of hepatitis B virus infection and interhost cellular responses using intrahepatic cholangiocyte organoids.

Autor: Lim CK; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Doherty Institute of Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.; Research Centre for Infectious Diseases and Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Romeo O; Research Centre for Infectious Diseases and Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Tran BM; Department of Infectious Diseases, Doherty Institute of Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia., Flanagan DJ; Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Kirby EN; Research Centre for Infectious Diseases and Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia., McCartney EM; Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, Victoria, Australia., Tse E; Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, Victoria, Australia., Vincan E; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Doherty Institute of Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia., Beard MR; Research Centre for Infectious Diseases and Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia.

Publikováno v: Journal of medical virology [J Med Virol] 2023 Nov; Vol. 95 (11), pp. e29232.

Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors.

Autor: Westhaus A; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Cabanes-Creus M; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Dilworth KL; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Zhu E; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Salas Gómez D; Gene Therapy and Regulation of Gene Expression Department, IdiSNA, Instituto de Investigación Sanitaria de Navarra, Universidad de Navarra, CIMA, Pamplona, Spain., Navarro RG; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Amaya AK; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Scott S; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Australian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Sydney, Australia., Kwiatek M; Military Institute of Hygiene and Epidemiology, The Biological Threats Identification and Countermeasure Centre, Puławy, Poland., McCorkindale AL; Inventia Life Science Pty Ltd., Sydney, Australia., Hayman TE; Inventia Life Science Pty Ltd., Sydney, Australia., Frahm S; Stem Cell Technology Platform, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany., Perocheau DP; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; Metabolic Medicine Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.; National Institute of Health Research Great Ormond Street Hospital Biomedical Research Centre, London, United Kingdom., Tran BM; Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Vincan E; Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Curtin Medical School, Curtin University, Perth, Australia., Wong SL; Molecular and Integrative Cystic Fibrosis (miCF) Research Centre, University of New South Wales and Sydney Children's Hospital, Sydney, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia., Waters SA; Molecular and Integrative Cystic Fibrosis (miCF) Research Centre, University of New South Wales and Sydney Children's Hospital, Sydney, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia.; Department of Respiratory Medicine, Sydney Children's Hospital, Faculty of Medicine, University of New South Wales, Sydney, Australia., Riddiough GE; Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Heidelberg, Australia., Perini MV; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Heidelberg, Australia., Wilson LOW; Australian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Sydney, Australia.; Applied BioSciences, Faculty of Science and Engineering, Macquarie University, Sydney, Australia., Baruteau J; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; Metabolic Medicine Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.; National Institute of Health Research Great Ormond Street Hospital Biomedical Research Centre, London, United Kingdom., Diecke S; Stem Cell Technology Platform, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany., González-Aseguinolaza G; Gene Therapy and Regulation of Gene Expression Department, IdiSNA, Instituto de Investigación Sanitaria de Navarra, Universidad de Navarra, CIMA, Pamplona, Spain., Santilli G; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Thrasher AJ; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Lisowski L; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Vector and Genome Engineering Facility, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warszawa, Poland.

Publikováno v: Human gene therapy [Hum Gene Ther] 2023 Apr; Vol. 34 (7-8), pp. 273-288.