Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tran, Lekhanh O."'
Autor:
Staas, Donnette D., Savage, Kelly L., Sherman, Vanessa L., Shimp, Heidi L., Lyle, Terry A., Tran, Lekhanh O., Wiscount, Catherine M., McMasters, Daniel R., Sanderson, Philip E.J., Williams, Peter D., Lucas, Bobby J., Jr., Krueger, Julie A., Dale Lewis, S., White, Rebecca B., Yu, Sean, Wong, Bradley K., Kochansky, Christopher J., Reza Anari, M., Yan, Youwei, Vacca, Joseph P.
Publikováno v:
In Bioorganic & Medicinal Chemistry 2006 14(20):6900-6916
Autor:
Vanessa L. Sherman, M. Reza Anari, Catherine M. Wiscount, Julie A. Krueger, Christopher J. Kochansky, Bobby J. Lucas, Tran Lekhanh O, Joseph P. Vacca, Terry A. Lyle, Bradley K. Wong, Sanderson Philip E, Heidi L. Shimp, Peter D. Williams, Sean Yu, Donnette D. Staas, Kelly L. Savage, S. Dale Lewis, Rebecca B. White, Youwei Yan, Daniel R. McMasters
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:6900-6916
Previous reports from our laboratories described potent tripeptide thrombin inhibitors which incorporate heterocycle-substituted chlorophenyl groups in the P1 position. Using these as lead compounds for further optimization, we identified sites of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0f376b03a161dd0c0e74d58d1df6a5
https://doi.org/10.1016/j.bmc.2006.06.040
https://doi.org/10.1016/j.bmc.2006.06.040
Autor:
Lori J. Gabryelski, Mark Embrey, Thorsten E. Fisher, Alysha M. Day, Linda T. Ecto, John S. Wai, Christopher J. Kochansky, Donnette D. Staas, Carl F. Homnick, Catherine M. Wiscount, Kara A. Stillmock, Michael D. Miller, Joseph P. Vacca, Tran Lekhanh O, Daria J. Hazuda, Peter J. Felock, Vanessa L. Sherman, Terry A. Lyle, M. Reza Anari, ZiQiang Wang, Daniel J. DiStefano, Peter D. Williams, William A. Schleif, Marc V. Witmer
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(16)
A series of 10-hydroxy-7,8-dihydropyrazino[1′,2′:1,5]pyrrolo[2,3- d ]pyridazine-1,9(2 H ,6 H )-diones was synthesized and tested for their inhibition of HIV-1 replication in cell culture. Structure–activity studies indicated that high antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dada49ba689c4c1df560dda97a0f8a0
https://pubmed.ncbi.nlm.nih.gov/18657970
https://pubmed.ncbi.nlm.nih.gov/18657970
Autor:
Adel M. Naylor-Olsen, Melissa S. Egbertson, Tran Lekhanh O, Thorsten E. Fisher, Kara A. Stillmock, Joseph P. Vacca, M. Katharine Holloway, Steven D. Young, James P. Guare, Peter J. Felock, Vanessa E. Grey, H. Marie Langford, Mark Embrey, John S. Wai, Linghang Zhuang, Daria J. Hazuda, Abigail Wolfe, Payne Linda S, William A. Schleif, Jeffrey Y. Melamed, Lori J. Gabryelski
Publikováno v:
Journal of medicinal chemistry. 43(26)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c145842551cba722b2a7f1512b450a5
https://pubmed.ncbi.nlm.nih.gov/11150161
https://pubmed.ncbi.nlm.nih.gov/11150161
Autor:
Wiscount, Catherine M., Williams, Peter D., Tran, Lekhanh O., Embrey, Mark W., Fisher, Thorsten E., Sherman, Vanessa, Homnick, Carl F., Donnette Staas, D., Lyle, Terry A., Wai, John S., Vacca, Joseph P., Wang, ZiQiang, Felock, Peter J., Stillmock, Kara A., Witmer, Marc V., Miller, Michael D., Hazuda, Daria J., Day, Alysha M., Gabryelski, Lori J., Ecto, Linda T., Schleif, William A., DiStefano, Daniel J., Kochansky, Christopher J., Reza Anari, M.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2008 18(16):4581-4583
Autor:
P. S. Anderson, William C. Lumma, Terry A. Lyle, Payne Linda S, Tran Lekhanh O, Joel R. Huff, Steven D. Young, S S Carroll, David B. Olsen, Susan F. Britcher
The clinical benefit of the human immunodeficiency virus type 1 (HIV-1) nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) is limited by the rapid selection of inhibitor-resistant viral variants. However, it may be possible to enhance the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d74dcf65b9950e2cfa7a255d8120c5
https://europepmc.org/articles/PMC162996/
https://europepmc.org/articles/PMC162996/
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