Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tram B. Doan"'
Autor:
Tram B. Doan, Vanessa Cheung, Colin D. Clyne, Heidi N. Hilton, Natalie Eriksson, Morag J. Young, John W. Funder, George E. O. Muscat, Peter J. Fuller, Christine L. Clarke, J. Dinny Graham
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-16 (2020)
Abstract Background The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling
Externí odkaz:
https://doaj.org/article/d75a54fc0c0d4205964f8c51ddcf97ff
Autor:
Rachel F. Dear, James French, Tram B. Doan, Michelle White, Elisabeth N. Elder, Jeremy Hsu, Stephen B. Fox, Rina Hui, Meagan Brennan, Paul R. Harnett, G. Bruce Mann, Elgene Lim, Farid Meybodi, Masrura Kabir, Nirmala Pathmanathan, Nicholas Wilcken, Phuong Dinh, Kirsty Stuart, Tim Wang, Verity Ahern, J. Dinny Graham
Publikováno v:
Breast Cancer Research and Treatment. 191:501-511
PURPOSE Genomic tests improve accuracy of risk prediction for early breast cancers but these are expensive. This study evaluated the clinical utility of EndoPredict®, in terms of impact on adjuvant therapy recommendations and identification of param
Autor:
Mahdi Moradi Marjaneh, Edwin P. Kirk, Ralph Patrick, Dimuthu Alankerage, David T. Humphreys, Gonzalo Del Monte-Nieto, Paola Cornejo-Paramo, Vaibhao Janbandhu, Tram B. Doan, Sally L. Dunwoodie, Emily S. Wong, Chris Moran, Ian C.A. Martin, Peter C. Thomson, Richard P. Harvey
Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely emergent phenomena arising from multilayer, multiscale and highly interconnected interactions. Atrial and ventricular septal defects are the most common fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb1d5ef3551c3b6e0b1bf051361d06f
https://doi.org/10.1101/2022.10.31.514499
https://doi.org/10.1101/2022.10.31.514499
Autor:
John W. Funder, Colin Clyne, Morag J Young, Vanessa Cheung, Tram B. Doan, Peter J. Fuller, J. Dinny Graham, Christine L. Clarke, George E.O. Muscat, Heidi N. Hilton, Natalie A. Eriksson
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-16 (2020)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling pathway
Autor:
Phuong, Dinh, J Dinny, Graham, Elisabeth N, Elder, Masrura, Kabir, Tram B, Doan, James, French, Farid, Meybodi, Rina, Hui, Nicholas R, Wilcken, Paul R, Harnett, Jeremy, Hsu, Kirsty E, Stuart, Tim, Wang, Verity, Ahern, Meagan, Brennan, Stephen B, Fox, Rachel F, Dear, Elgene, Lim, Michelle, White, G Bruce, Mann, Nirmala, Pathmanathan
Publikováno v:
Breast cancer research and treatment. 191(3)
Genomic tests improve accuracy of risk prediction for early breast cancers but these are expensive. This study evaluated the clinical utility of EndoPredict®, in terms of impact on adjuvant therapy recommendations and identification of parameters to
Publikováno v:
Journal of Molecular Endocrinology. 58:R169-R190
Nuclear receptors (NRs) have been targets of intensive drug development for decades due to their roles as key regulators of multiple developmental, physiological and disease processes. In breast cancer, expression of the estrogen and progesterone rec
Autor:
John W. Funder, Elizabeth Kuczek, Evan R. Simpson, George E.O. Muscat, Colin Clyne, Peter J. Leedman, Dinny Graham, Christine L. Clarke, Tram B. Doan, Peter J. Fuller, Natalie A. Eriksson, Wayne D. Tilley
Publikováno v:
Molecular Oncology. 8:998-1013
Although molecular signatures based on transcript expression in breast cancer samples have provided new insights into breast cancer classification and prognosis, there are acknowledged limitations in current signatures. To provide rational, pathway
Autor:
Samantha R. Oakes, Lily I. Huschtscha, Peter J. Leedman, Audrey Silvestri, Christopher J. Ormandy, Tram B. Doan, Christine L. Clarke, Silke Kantimm, Wayne D. Tilley, Nicole Santucci, George E.O. Muscat, Peter J. Fuller, Heidi N. Hilton, Evan R. Simpson, J. Dinny Graham, John W. Funder, Elizabeth Kuczek
Publikováno v:
Oncotarget
Cumulative exposure to estrogen (E) and progesterone (P) over the menstrual cycle significantly influences the risk of developing breast cancer. Despite the dogma that PR in the breast merely serves as a marker of an active estrogen receptor (ER), an
Autor:
Mahdi Moradi Marjaneh, Edwin P Kirk, Ralph Patrick, Dimuthu Alankarage, David T Humphreys, Gonzalo Del Monte-Nieto, Paola Cornejo-Paramo, Vaibhao Janbandhu, Tram B Doan, Sally L Dunwoodie, Emily S Wong, Chris Moran, Ian CA Martin, Peter C Thomson, Richard P Harvey
Publikováno v:
eLife, Vol 12 (2023)
Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely to be emergent phenomena arising from multilayer, multiscale, and highly interconnected interactions. Atrial and ventricular septal defects are the most co
Externí odkaz:
https://doaj.org/article/b0e177240240418384f4ea4e88aaa1c8