Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tracy Weiss"'
Autor:
Yushan Wang, Thomas W. Sawyer, Yiu Chung Tse, Changyang Fan, Grant Hennes, Julia Barnes, Tyson Josey, Tracy Weiss, Peggy Nelson, Tak Pan Wong
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Traumatic brain injury (TBI) due to blast from improvised explosive devices has been a leading cause of morbidity and mortality in recent conflicts in Iraq and Afghanistan. However, the mechanisms of primary blast-induced TBI are not well understood.
Externí odkaz:
https://doaj.org/article/b509053722e9406baebf30cebb146f73
Autor:
Julia Barnes, Grant Hennes, Thomas W. Sawyer, Tracy Weiss, Changyang Fan, Tak Pan Wong, Tyson Josey, Yiu Chung Tse, Peggy Nelson, Yushan Wang
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Traumatic brain injury (TBI) due to blast from improvised explosive devices has been a leading cause of morbidity and mortality in recent conflicts in Iraq and Afghanistan. However, the mechanisms of primary blast-induced TBI are not well understood.
Autor:
M. Tracy Weiss, Claire Beaup, Yushan Wang, Frédéric Dorandeu, André Peinnequin, Catherine Tenn
Publikováno v:
Toxicology Letters. 210:71-77
The link between cell death and increased cyclooxygenases-2 (COX-2) activity has not been clearly established. In this study, we examined whether COX-2 activation contributed to the mechanism of neurotoxicity produced by an organophosphorous nerve ag
Autor:
Catherine Tenn, Yushan Wang, Cory Vair, M. Tracy Weiss, Junfei Yin, Robert Frew, Peggy Nelson, Thomas W. Sawyer
Publikováno v:
Toxicon. 54:95-102
Maitotoxin (MTX) is one of the most potent toxins known to date. It causes massive calcium (Ca(2+)) influx and necrotic cell death in various tissues. However, the exact mechanism(s) underlying its cellular toxicity is not fully understood. In the pr
Publikováno v:
Neurotoxicity Research. 13:163-172
Exposure of the central nervous system to organophosphorus (OP) nerve agents induces seizures and neuronal cell death. Here we report that the OP nerve agent, VX, induces apoptotic-like cell death in cultured rat cortical neurons. The VX effects on n
Publikováno v:
Toxicon. 51:1400-1408
The highly potent marine toxin maitotoxin (MTX) evoked an increase in cytosolic Ca 2+ levels in fura-2 loaded rat aortic smooth muscle cells, which was dependent on extracellular Ca 2+ . This increase was almost fully inhibited by KB-R7943, a potent
Autor:
David V. Ritzel, Mercy Villanueva, Cory Vair, Changyang Fan, Tracy Weiss, Thomas W. Sawyer, Peggy Nelson, Grant Hennes, Yushan Wang, Julia Barnes, Tyson Josey, Yimin Shei
Publikováno v:
Journal of neurotrauma. 33(13)
The role of primary blast in blast-induced traumatic brain injury (bTBI) is controversial in part due to the technical difficulties of generating free-field blast conditions in the laboratory. The use of traditional shock tubes often results in artif
Publikováno v:
Neurotoxicity research. 20(4)
Exposure of the central nervous system to organophosphorus (OP) nerve agents causes seizures and neuronal cell death. Benzodiazepines are commonly used to treat seizures induced by OPs. However, it is known that soman-induced seizures are particularl
Publikováno v:
Toxicology. 100(1-3)
The toxicity of the chemical warfare agent sulphur mustard, (bis-(2-chloroethyl)sulphide, HD), was examined in adult rat lung organ cultures. Assessment of HD-induced damage by the MTT cytotoxicity assay indicated that the median lethal concentration
Publikováno v:
Journal of applied toxicology : JAT. 12(1)
A soil sample originating from an area of suspected chemical warfare activity was subjected to chemical analysis and bioassay. Sarin and several related compounds were confirmed in the soil by capillary column gas chromatography-mass spectrometry (GC