Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tracy Timkey"'
Autor:
Kevin T. Chapman, Tracy Timkey, Margarita Garcia-Calvo, Vicky M. Houtzager, Dita M. Rasper, Donald W. Nicholson, Erin P. Peterson, Nancy A. Thornberry, Thomas A. Rano, Sophie Roy, John P. Vaillancourt, Penny A. Nordstrom
Publikováno v:
Journal of Biological Chemistry. 272:17907-17911
There is compelling evidence that members of the caspase (interleukin-1beta converting enzyme/CED-3) family of cysteine proteases and the cytotoxic lymphocyte-derived serine protease granzyme B play essential roles in mammalian apoptosis. Here we use
Autor:
Jennifer Rotonda, Donald W. Nicholson, Kevin T. Chapman, Erin P. Peterson, Thomas A. Rano, Nancy A. Thornberry, Tracy Timkey, Joseph W. Becker
Publikováno v:
Chemistrybiology. 4(2)
Background: Interleukin-1β converting enzyme (ICE/caspase-1) is the protease responsible for interleukin-1β (IL-1β) production in monocytes. It was the first member of a new cysteine protease family to be identified. Members of this family have fu