Reflecting on COVID-19 vaccine hesitancy among South Asian communities in the UK: A learning curve to decolonising the secondary school curriculum

Autor: Anqi Hu, Tracy Nissan, Md Zahidul Islam Pranjol

Publikováno v: Frontiers in Education, Vol 8 (2023)

COVID-19 has brought to light the systemic racism faced by ethnic minorities in the UK. During the pandemic, we saw an increase in anti-Asian hate crimes and a lack of support from the government given to both patients and healthcare workers from min

Externí odkaz: https://doaj.org/article/f13c68dcc6ac4335a6d13777e06fd366

Hiding in Plain Sight: Formation and Function of Stress Granules During Microbial Infection of Mammalian Cells

Autor: Alistair Tweedie, Tracy Nissan

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

Stress granule (SG) formation is a host cell response to stress-induced translational repression. SGs assemble with RNA-binding proteins and translationally silent mRNA. SGs have been demonstrated to be both inhibitory to viruses, as well as being su

Externí odkaz: https://doaj.org/article/9d69facf08ed440387e3eddbaf9cee82

The decapping activator Edc3 and the Q/N-rich domain of Lsm4 function together to enhance mRNA stability and alter mRNA decay pathway dependence in Saccharomyces cerevisiae

Autor: Susanne Huch, Maren Müller, Mridula Muppavarapu, Jessie Gommlich, Vidya Balagopal, Tracy Nissan

Publikováno v: Biology Open, Vol 5, Iss 10, Pp 1388-1399 (2016)

The rate and regulation of mRNA decay are major elements in the proper control of gene expression. Edc3 and Lsm4 are two decapping activator proteins that have previously been shown to function in the assembly of RNA granules termed P bodies. Here, w

Externí odkaz: https://doaj.org/article/e893b5d4206d4225ac6369ff008d1931

Data from SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells

Autor: Leandro Castellano, Justin Stebbing, Igor Ulitsky, Keith W. Vance, Tracy Nissan, Alistair Tweedie, Ylenia Lombardo, Neta Degani, Silvia Ottaviani, Angela Yiu, Paul Cathcart, Nuria Casas-Vila, Mark Kalisz, Aleksandra Dabrowska, Alex de Giorgio, Sladjana Zagorac

In many tumors, cells transition reversibly between slow-proliferating tumor-initiating cells (TIC) and their differentiated, faster-growing progeny. Yet, how transcriptional regulation of cell-cycle and self-renewal genes is orchestrated during thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77c3ca4e742f39a2740ce26ba34d2fae
https://doi.org/10.1158/0008-5472.c.6512499.v1

SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells

Autor: Justin Stebbing, Tracy Nissan, Angela Yiu, Aleksandra Dabrowska, Leandro Castellano, Keith W. Vance, Sladjana Zagorac, Nuria Casas-Vila, Alex de Giorgio, Ylenia Lombardo, Paul Cathcart, Igor Ulitsky, Silvia Ottaviani, Mark Kalisz, Neta Degani, Alistair Tweedie

Publikováno v: Zagorac, S, de Giorgio, A, Dabrowska, A, Kalisz, M, Casas-Vila, N, Cathcart, P, Yiu, A, Ottaviani, S, Degani, N, Lombardo, Y, Tweedie, A, Nissan, T, Vance, K W, Ulitsky, I, Stebbing, J & Castellano, L 2021, ' SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells ', Cancer Research, vol. 81, no. 3, pp. 580-593 . https://doi.org/10.1158/0008-5472.CAN-20-2612

In many tumors, cells transition reversibly between slow-proliferating tumor-initiating cells (TIC) and their differentiated, faster-growing progeny. Yet, how transcriptional regulation of cell-cycle and self-renewal genes is orchestrated during thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0906db9c83d79e27c9327321ed1a97ba
https://doi.org/10.1158/0008-5472.can-20-2612