Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tracy McGaha"'
Autor:
Derek L. Clouthier, Scott C. Lien, S. Y. Cindy Yang, Linh T. Nguyen, Venkata S. K. Manem, Diana Gray, Michael Ryczko, Albiruni R. A. Razak, Jeremy Lewin, Stephanie Lheureux, Ilaria Colombo, Philippe L. Bedard, David Cescon, Anna Spreafico, Marcus O. Butler, Aaron R. Hansen, Raymond W. Jang, Sangeet Ghai, Ilan Weinreb, Valentin Sotov, Ramy Gadalla, Babak Noamani, Mengdi Guo, Sawako Elston, Amanda Giesler, Sevan Hakgor, Haiyan Jiang, Tracy McGaha, David G. Brooks, Benjamin Haibe-Kains, Trevor J. Pugh, Pamela S. Ohashi, Lillian L. Siu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Immune checkpoint inhibitors (ICIs) demonstrate unprecedented efficacy in multiple malignancies; however, the mechanisms of sensitivity and resistance are poorly understood and predictive biomarkers are scarce. INSPIRE is a phase
Externí odkaz:
https://doaj.org/article/31ba8dd2f028423db6db252c1c7723fb
Autor:
Shiyan Wang, Shanshan Gao, Yong Zeng, Lin Zhu, Yulin Mo, Chi Chun Wong, Yi Bao, Peiran Su, Jianning Zhai, Lina Wang, Fraser Soares, Xin Xu, Huarong Chen, Kebria Hezaveh, Xinpei Ci, Aobo He, Tracy McGaha, Catherine O’Brien, Robert Rottapel, Wei Kang, Jianfeng Wu, Gang Zheng, Zongwei Cai, Jun Yu, Housheng Hansen He
Publikováno v:
Gastroenterology. 162(4)
N6-methyladenosine (mYTH N6-methyladenosine RNA binding protein 1 (Ythdf1) knockout mouse was generated to determine the effect of Ythdf1 in CRC tumorigenesis in vivo. Multiomic analysis of RNA-sequencing, mDNA copy number gain of YTHDF1 is a frequen
Autor:
Shiyan Wang, Shanshan Gao, Yong Zeng, Lin Zhu, Chi Chun Wong, Yi Bao, Peiran Su, Jianning Zhai, Lina Wang, Fraser Soares, Xin Xu, Huarong Chen, Kebria Hezaveh, Yulin Mo, Xinpei Ci, Aobo He, Tracy McGaha, Catherine O'Brien, Robert Rottapel, Wei Kang, Jianfeng Wu, Gang Zheng, Zongwei Cai, Jun Yu, Housheng Hansen He
Publikováno v:
Gastroenterology. 162:S-73
Autor:
Kebria Hezaveh, Rahul Shinde, Andreas Klotegen, Marie Jo Halaby, Sara Lamorte, Teresa Ciudad, Barbara Gruenwald, Elisabeth G. Foerster, Danica Chaharlangi, Mengdi Guo, Luke Neufeld, Kitty Liu, Priya Makijani, Trevor J. Pugh, Devanand Pinto, Ileana Co, Alison McGuigan, Gun Ho Jang, Rama Kokha, Pamela S. Ohashi, Grainne O'Kane, Steven Gallinger, William W. Navarre, Heather Maughan, Dana J. Philpott, David G. Brooks, Tracy McGaha
Publikováno v:
SSRN Electronic Journal.
Autor:
Marc Oliva Bernal, Douglas Chepeha, Amy Prawira, Douglass Vines, Anna Spreafico, Scott Bratman, John De Almeida, Aaron Hansen, David Goldstein, Ralph Gilbert, Patrick Gullane, Dale H. Brown, Ilan Weinreb, Bayardo Perez-Ordoñez, Pamela S. Ohashi, Tracy McGaha, Ben X. Wang, Jonathan Irish, Isan Chen, Lillian L. Siu
Publikováno v:
Cancer Research. 79:CT124-CT124
Background: Squamous cell carcinoma of the oral cavity (SCCOC) often presents at early stages but its prognosis remains guarded, with a 5-year survival rate of 60% despite curative-intent therapies. Preoperative window-of-opportunity (WOO) studies in
Autor:
Rahul Suresh Shinde, Kebria Hezaveh, Marie Jo Halaby, Andreas Kloetgen, Sara Lamorte, David Munn, Aristotelis Tsirigos, Michael Madaio, Sussane Gabrielsson, Joan Wither, Daniel De Carvalho, Tracy McGaha
Publikováno v:
The Journal of Immunology. 200:175.6-175.6
The Aryl hydrocarbon receptor (AhR) can potently modulate immunity at multiple levels, but its mechanistic role in immune regulation is still being elucidated. Here we show phagocytes exposed to apoptotic cells exhibit rapid activation of AhR driving
Autor:
Rahul Suresh Shinde, Kebria Hezaveh, Lara Utsch, Sara Lamorte, Buvana Ravishankar, Haiyun Liu, Kapil Chaudhary, Tiago Medina, Andreas Kloetgen, Marie Jo Halaby, Michael Madaio, Joan Wither, Aristotelis Tsirigos, Daniel De Carvalho, David Munn, Tracy McGaha
Publikováno v:
The Journal of Immunology. 198:224.15-224.15
Tissue-resident macrophages (MΦ) are crucial in driving tolerance and preventing systemic autoimmunity. We have previously shown that exposure to apoptotic cells triggers a regulatory circuit dependent on IL-10 production in resident MΦ. However, k
Autor:
Amy Paschall, Ruihua Zhang, Kankana Bardhan, Chen-Feng Qi, Liang Peng, Geming Lu, Jianjun Yang, Miriam Merad, Mary Zimmerman, Tracy McGaha, Gang Zhou, Andrew Mellor, Scott I. Abrams, Herbert Morse, Keiko Ozato, Huabao Xiong, Kebin Liu
Publikováno v:
Cancer Immunology Research. 3:A84-A84
This abstract is being presented as a short talk in the scientific program. A full abstract is printed in the Proffered Abstracts section (PR05) of the Conference Proceedings. Citation Format: Amy Paschall, Ruihua Zhang, Kankana Bardhan, Chen-Feng Qi
Autor:
Amy Paschall, Rui-hua Zhang, Chen-Feng Qi, Kankana Bardhan, Liang Peng, Geming Lu, Jianjun Yang, Miriam Merad, Tracy McGaha, Gang Zhou, Andrew Mellor, Scott Abrams, Herbert Morse, Keiko Ozato, Huabao Xiong, Kebin Liu
Publikováno v:
The Journal of Immunology. 194:141.3-141.3
During hematopoiesis, hematopoietic stem cells differentiate into granulocytes and macrophages via a distinct differentiation program that is controlled by myeloid lineage-specific transcription factors. Mice with a null mutation of IFN Regulatory Fa
Publikováno v:
The Journal of Immunology. 192:127.11-127.11
T cell independent (TI) antibody responses are crucial for humoral immunity to viruses and encapsulated bacteria. Here we report a novel mechanism where the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) 1 regulates the B cell respo