Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tracy Matray"'
Autor:
Tracy Matray, Sharat Singh, Hesham Sherif, Kenneth Farber, Erin Kwang, Michael VanBrunt, Eriko Matsui, Hiroaki Yada
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243218 (2020)
In the pursuit of a novel class of fluorescent dyes we have developed a programmable polymer system that enables the rational design and control of macromolecular constructs through simple control of polymer primary sequence. These polymers are assem
Externí odkaz:
https://doaj.org/article/7fed09ee2f8140aca406457f2cd70faa
Autor:
Eriko Matsui, Sharat Singh, Kenneth Farber, Michael Vanbrunt, Erin Kwang, Hiroaki Yada, Tracy Matray, Hesham Sherif
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243218 (2020)
PLoS ONE, Vol 15, Iss 12, p e0243218 (2020)
In the pursuit of a novel class of fluorescent dyes we have developed a programmable polymer system that enables the rational design and control of macromolecular constructs through simple control of polymer primary sequence. These polymers are assem
Autor:
Marie-Annick Marloie-Provost, Cristiana Guiducci, Franck J. Barrat, Yong-Jun Liu, Vassili Soumelis, Robert L. Coffman, Tracy Matray, Cristina Ghirelli
Publikováno v:
The Journal of Experimental Medicine
Plasmacytoid predendritic cells (pDCs) are the main producers of type I interferon (IFN) in response to Toll-like receptor (TLR) stimulation. Phosphatidylinositol-3 kinase (PI3K) has been shown to be activated by TLR triggering in multiple cell types
Autor:
Robert L. Coffman, Franck J. Barrat, Jean H. Chan, Carlo Calacsan, Emily Damon, Tracy Matray, Cristiana Guiducci, Gary Ott, Kyung Dall Lee
Publikováno v:
The Journal of Experimental Medicine
Human plasmacytoid dendritic cells (PDCs) can produce interferon (IFN)-alpha and/or mature and participate in the adaptive immune response. Three classes of CpG oligonucleotide ligands for Toll-like receptor (TLR)9 can be distinguished by different s
Publikováno v:
Nucleic Acids Research. 30:5561-5569
DNA polymerases specifically insert the hydrophobic pyrene deoxynucleotide (P) opposite tetrahydrofuran (F), an stable abasic site analog, and DNA duplexes containing this non-hydrogen-bonded pair possess a high degree of thermodynamic stability. The
Autor:
Eric T. Kool, Tracy Matray
Publikováno v:
Nature. 399:704-708
In most models of DNA replication, Watson-Crick hydrogen bonding drives the incorporation of nucleotides into the new strand of DNA and maintains the complementarity of bases with the template strand. Studies with nonpolar analogues of thymine and ad
Publikováno v:
Biochemistry. 37:7757-7763
Various forms of oxidative stress, including gamma-radiolysis and UV irradiation, result in the formation of damaged bases. (5R)-Thymidine C5-hydrate is one of several modified nucleosides produced from thymidine under these conditions. N-(2-Deoxy-be
Autor:
Tracy Matray, Marc M. Greenberg
Publikováno v:
Biochemistry. 36:14071-14079
Oligonucleotides containing 5R-5,6-dihydro-5-hydroxythymidine (5R-3) and structural analogue 5,6-dihydro-5-methylthymidine (9) at defined sites were chemically synthesized via a method that obviates the use of NH4OH. Oligonucleotides prepared by this
Autor:
Hariharan Venkatesan, Mark R. Barvian, Brian K. Goodman, Marc M. Greenberg, Tracy Matray, Gary P. Cook, and Christopher Tronche
Publikováno v:
Journal of the American Chemical Society. 119:1828-1839
5,6-Dihydrothymid-5-yl (4) is generated via Norrish type I cleavage of isopropyl ketone 7. Ketone 7 was site specifically incorporated into chemically synthesized polythymidylates and an oligonucleotide containing all four native deoxyribonucleotides
Autor:
Eric T. Kool, Tracy Matray
Publikováno v:
Journal of the American Chemical Society. 120(24)
Noncovalent interactions between aromatic nucleobases are the major stabilizing forces which contribute to the structural integrity of duplex DNA and RNA.1–3 However, base pairing in nucleic acids is a consequence of more than just hydrogen bonding