Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tracy L. Wolfe"'
Autor:
Chad N. Hancock, Luke H. Stockwin, Dianne L. Newton, Suzanne Borgel, Lawrence R. Phillips, Melinda G. Hollingshead, Sherry X. Yu, Tracy L. Wolfe
Publikováno v:
International Journal of Cancer. 127:2510-2519
The "Warburg effect," also termed aerobic glycolysis, describes the increased reliance of cancer cells on glycolysis for ATP production, even in the presence of oxygen. Consequently, there is continued interest in inhibitors of glycolysis as cancer t
Autor:
Lawrence R. Phillips, Tyra House, Tracy L. Wolfe, John Buckley, Chris Bramhall, Sherman F. Stinson
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 741:205-211
During the course of our study to develop analytical methodology for quantitating the investigative antitumor agent 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-4H-1-benzopyran -4-one (DAF; NSC 686288) in plasma, a significant concentrati
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 16:1301-1309
Breflate is a water soluble prodrug developed to facilitate parenteral administration of the investigational antineoplastic agent brefeldin A (BFA). Previously, using analytical methods based upon reversed-phase high performance liquid chromatography
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 688:354-358
A simple and sensitive isocratic high-performance liquid chromatographic (HPLC) method with UV detection for the quantitation of perillic acid, a major circulating metabolite of perillyl alcohol and d-limonene, in plasma is described. Sample preparat
Publikováno v:
Synthetic Communications. 26:1805-1814
Two efficient syntheses of 3-chloro-7-[(chlorocarbonyl)methoxy]-4-methylcoumarin are described, one utilizing traditional chemistry starting from 3-chloro-7-hydroxy-4-methylcoumarin, while the other uses a novel reagent, sulfuryl chloride/thionyl chl
Publikováno v:
ChemInform. 27
Two efficient syntheses of 3-chloro-7-[(chlorocarbonyl)methoxy]-4-methylcoumarin are described, one utilizing traditional chemistry starting from 3-chloro-7-hydroxy-4-methylcoumarin, while the other uses a novel reagent, sulfuryl chloride/thionyl chl
Autor:
Sherman F. Stinson, Maria I. Rivera, Tracy L. Wolfe, Kaye Upadhyay, Lawrence R. Phillips, Jean L Jorden
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 767(1)
Alpha-Terthienyl (1) is a trithiophene found widely distributed in plants. Other naturally occurring trithiophenes are less widely distributed, but nonetheless exhibit potent antiviral and cytotoxic activities. A synthetic analog of 1, 2,5-bis(5-hydr
Autor:
Lawrence R. Phillips, Robert J. Fisher, Eric M. Towler, Stephen B. Fox, Stephen Campbell, Haleem J. Issaq, Tracy L. Wolfe, Alan Rein
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 98(19)
HIV-1 Gag protein assembles into 100- to 120-nm diameter particles in mammalian cells. Recombinant HIV-1 Gag protein assembles in a fully defined system in vitro into particles that are only 25–30 nm in diameter and that differ significantly in oth