Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Tracy L Stockley"'
Autor:
Esmail M Al-Ezzi, Zachary W Veitch, Samer H Salah, Theodorus H Van der Kwast, Tracy L Stockley, Shamini Selvarajah, Tong Zhang, Srikala S Sridhar, Adrian G Sacher, Nazanin Fallah-Rad, Girish S Kulkarni, Alexandre R Zlotta, Antonio Finelli, Aaron R Hansen
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259272 (2021)
BackgroundNon-schistosomiasis related-squamous cell carcinoma of urinary bladder (NSR-SCCUB) is a rare tumor subtype distinct from urothelial carcinoma (UC). Studies assessing molecular biomarkers in bladder cancer have generally focused on UC, and g
Externí odkaz:
https://doaj.org/article/e3799ed33ecf4271a5cb805e2c0260da
Autor:
Shelley Kuang, Kaitlin Chen, Sachin Sayal, Gajeni Prabahan, Mary R. Rabey, Lisa W. Le, Andrew Seto, Frances A. Shepherd, Geoffrey Liu, Penelope Bradbury, Adrian G. Sacher, Jennifer H. Law, Peter Sabatini, Tracy L. Stockley, Ming S. Tsao, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4476-4485 (2024)
In advanced non-squamous non-small-cell lung cancer (NSCLC), routine testing with next-generation sequencing (NGS) is recommended to identify actionable genomic alterations (AGAs). The therapeutic implications of repeated NGS testing on synchronous a
Externí odkaz:
https://doaj.org/article/b1046990507e43358bd21c8d115538a3
Autor:
Alberto Hernando-Calvo, Paul Nguyen, Philippe L. Bedard, Kelvin K.W. Chan, Ramy R. Saleh, Deirdre Weymann, Celeste Yu, Eitan Amir, Dean A. Regier, Bishal Gyawali, Danielle Kain, Brooke Wilson, Craig C. Earle, Nicole Mittmann, Albiruni R. Abdul Razak, Wanrudee Isaranuwatchai, Peter Sabatini, Anna Spreafico, Tracy L. Stockley, Trevor J. Pugh, Christine Williams, Lillian L. Siu, Timothy P. Hanna
Publikováno v:
EClinicalMedicine, Vol 69, Iss , Pp 102443- (2024)
Summary: Background: To date, economic analyses of tissue-based next generation sequencing genomic profiling (NGS) for advanced solid tumors have typically required models with assumptions, with little real-world evidence on overall survival (OS), cl
Externí odkaz:
https://doaj.org/article/19ab2f66fed24a75a727e76111c21e84
Autor:
Meghan J. Walker, Kristina M. Blackmore, Amy Chang, Laurence Lambert-Côté, Annie Turgeon, Antonis C. Antoniou, Kathleen A. Bell, Mireille J. M. Broeders, Jennifer D. Brooks, Tim Carver, Jocelyne Chiquette, Philippe Després, Douglas F. Easton, Andrea Eisen, Laurence Eloy, D. Gareth Evans, Samantha Fienberg, Yann Joly, Raymond H. Kim, Shana J. Kim, Bartha M. Knoppers, Aisha K. Lofters, Hermann Nabi, Jean-Sébastien Paquette, Nora Pashayan, Amanda J. Sheppard, Tracy L. Stockley, Michel Dorval, Jacques Simard, Anna M. Chiarelli
Publikováno v:
Cancers, Vol 16, Iss 11, p 2116 (2024)
Risk-stratified breast screening has been proposed as a strategy to overcome the limitations of age-based screening. A prospective cohort study was undertaken within the PERSPECTIVE I&I project, which will generate the first Canadian evidence on mult
Externí odkaz:
https://doaj.org/article/8a68e19c738f4a9cba3c62f7e4dedcb4
Autor:
Tracy L. Stockley, Bryan Lo, Adrian Box, Andrea Gomez Corredor, John DeCoteau, Patrice Desmeules, Harriet Feilotter, Daria Grafodatskaya, Cynthia Hawkins, Weei Yuarn Huang, Iyare Izevbaye, Guylaine Lepine, Andreas I. Papadakis, Paul C. Park, Brandon S. Sheffield, Danh Tran-Thanh, Stephen Yip, Ming Sound Tsao
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 3989-3997 (2023)
The detection of gene fusions by RNA-based next-generation sequencing (NGS) is an emerging method in clinical genetic laboratories for oncology biomarker testing to direct targeted therapy selections. A recent Canadian study (CANTRK study) comparing
Externí odkaz:
https://doaj.org/article/24b1f17f55c2433ebe284fadc6a7249a
Autor:
Diana N. Ionescu, Tracy L. Stockley, Shantanu Banerji, Christian Couture, Cheryl A. Mather, Zhaolin Xu, Normand Blais, Parneet K. Cheema, Quincy S.-C. Chu, Barbara Melosky, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4981-4997 (2022)
Non-small cell lung cancer (NSCLC) has historically been associated with a poor prognosis and low 5-year survival, but the use of targeted therapies in NSCLC has improved patient outcomes over the past 10 years. The pace of development of new targete
Externí odkaz:
https://doaj.org/article/1ed9d430c59d4d3496913a7bcdcbbc84
Autor:
Shelley Kuang, Andrea S. Fung, Kirstin A. Perdrizet, Kaitlin Chen, Janice J. N. Li, Lisa W. Le, Michael Cabanero, Ola Abu Al Karsaneh, Ming S. Tsao, Josh Morganstein, Laura Ranich, Adam C. Smith, Cuihong Wei, Carol Cheung, Frances A. Shepherd, Geoffrey Liu, Penelope Bradbury, Prodipto Pal, Joerg Schwock, Adrian G. Sacher, Jennifer H. Law, Tracy L. Stockley, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4428-4437 (2022)
In advanced non-small cell lung cancer (NSCLC), patients with actionable genomic alterations may derive additional clinical benefit from targeted treatment compared to cytotoxic chemotherapy. Current guidelines recommend extensive testing with next g
Externí odkaz:
https://doaj.org/article/1eeb191a55df4e19870dc32a209c27eb
Autor:
Jeanna M. McCuaig, Sarah E. Ferguson, Danielle Vicus, Karen Ott, Tracy L. Stockley, Raymond H. Kim, Kelly A. Metcalfe
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Reflex (automatic) BRCA1 and BRCA2 (BRCA1/2) genetic testing of tumour tissue is being completed for all newly diagnosed high-grade serous ovarian cancer (HGSOC) in the province of Ontario, Canada. The objective of this study was
Externí odkaz:
https://doaj.org/article/40ae4b7e413e4d5f8c9a22e16b5adce5
Autor:
Leslie E. Oldfield, Jessica Grzybowski, Sylvie Grenier, Elizabeth Chao, Gregory S. Downs, Kirsten M. Farncombe, Tracy L. Stockley, Ozgur Mete, Raymond H. Kim
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-5 (2022)
Abstract Von Hippel-Lindau disease (VHL) is an autosomal dominant, inherited syndrome with variants in the VHL gene causing predisposition to multi-organ benign and malignant neoplasms. A germline VHL variant is identified in 95–100% of individuals
Externí odkaz:
https://doaj.org/article/cdf9e2fa2df24b4ab8df4e80fa08a011
Autor:
Kirstin Perdrizet, Tracy L. Stockley, Jennifer H. Law, Adam Smith, Tong Zhang, Roxanne Fernandes, Muqdas Shabir, Peter Sabatini, Nadia Al Youssef, Christine Ishu, Janice JN Li, Ming-Sound Tsao, Prodipto Pal, Michael Cabanero, Joerg Schwock, Hyang Mi Ko, Scott Boerner, Heather Ruff, Frances A. Shepherd, Penelope A. Bradbury, Geoffrey Liu, Adrian G. Sacher, Natasha B. Leighl
Publikováno v:
Cancer Treatment and Research Communications, Vol 31, Iss , Pp 100534- (2022)
Objectives: Standard molecular testing for patients with stage IV non-small cell lung cancer (NSCLC) in the Canadian publicly funded health system includes single gene testing for EGFR, ALK, and ROS-1. Comprehensive genomic profiling (CGP) may broade
Externí odkaz:
https://doaj.org/article/efa5907711174a89a85365493ff18f7d