Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tracy L, Swanson"'
Autor:
Ewa Galaj, Guo-Hua Bi, Benjamin Klein, Briana Hempel, Anver Basha Shaik, Emma S. Gogarnoiu, Jacob Friedman, Jenny Lam, Rana Rais, John F. Reed, Shelley H. Bloom, Tracy L. Swanson, Jennifer L. Schmachtenberg, Amy J. Eshleman, Aaron Janowsky, Zheng-Xiong Xi, Amy Hauck Newman
Publikováno v:
Neuropsychopharmacology. 47:2309-2318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d8581437ec2390de249cb8d99bc1090
https://doi.org/10.1038/s41386-022-01379-1
https://doi.org/10.1038/s41386-022-01379-1
Autor:
Laura B. Kozell, Amy J. Eshleman, Tracy L. Swanson, Shelley H. Bloom, Katherine M. Wolfrum, Jennifer L. Schmachtenberg, Randall J. Olson, Aaron Janowsky, Atheir I. Abbas
Publikováno v:
J Pharmacol Exp Ther
Novel psychoactive substances, including synthetic substituted tryptamines, represent a potential public health threat. Additionally, some substituted tryptamines are being studied under medical guidance as potential treatments of psychiatric disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c873bdb6d466b99885f6445a49a7ca
https://europepmc.org/articles/PMC10029822/
https://europepmc.org/articles/PMC10029822/
Autor:
Jenna M. Ramaker, Robert S. Cargill, Tracy L Swanson, Hanil Quirindongo, Marlène Cassar, Doris Kretzschmar, Philip F. Copenhaver
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Proteolytic processing of the Amyloid Precursor Protein (APP) produces beta-amyloid (Aβ) peptide fragments that accumulate in Alzheimer’s Disease (AD), but APP may also regulate multiple aspects of neuronal development, albeit via mechanisms that
Externí odkaz:
https://doaj.org/article/129df5b729ab47b5a9622ea1be2f45df
Autor:
Jennifer L. Schmachtenberg, John F. Reed, Randy Torralva, Tracy L. Swanson, William E. Schutzer, Katherine M. Wolfrum, Amy J. Eshleman, Shelley H. Bloom, Aaron Janowsky
Publikováno v:
J Pharmacol Exp Ther
Synthetic opioids, including fentanyl and its analogs, have therapeutic efficacy in analgesia and anesthesia. However, their illicit use in the United States has increased and contributed to the number one cause of death for adults 18–50 years old.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e92ee3ca2ff2d4f14709bce93e7be2
https://doi.org/10.1124/jpet.120.265561
https://doi.org/10.1124/jpet.120.265561
Autor:
Ewa, Galaj, Guo-Hua, Bi, Benjamin, Klein, Briana, Hempel, Anver Basha, Shaik, Emma S, Gogarnoiu, Jacob, Friedman, Jenny, Lam, Rana, Rais, John F, Reed, Shelley H, Bloom, Tracy L, Swanson, Jennifer L, Schmachtenberg, Amy J, Eshleman, Aaron, Janowsky, Zheng-Xiong, Xi, Amy Hauck, Newman
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(13)
The non-medical use of opioids has become a national crisis in the USA. Developing non-opioid pharmacotherapies for controlling this opioid epidemic is urgent. Dopamine D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f2d1b8117627a0d92163cd64304df59
https://pubmed.ncbi.nlm.nih.gov/35879349
https://pubmed.ncbi.nlm.nih.gov/35879349
Autor:
Jill S. Wentzell, Bonnie J. Bolkan, Katia Carmine-Simmen, Tracy L. Swanson, Derek T. Musashe, Doris Kretzschmar
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 78-87 (2012)
The processing of Amyloid Precursor Proteins (APPs) results in several fragments, including soluble N-terminal ectodomains (sAPPs) and C-terminal intracellular domains (AICD). sAPPs have been ascribed neurotrophic or neuroprotective functions in cell
Externí odkaz:
https://doaj.org/article/33045ddec3b049e5b1df7a6bf5d889a5
Autor:
Philip F. Copenhaver, Thimmappa S. Anekonda, Derek Musashe, Kristine M. Robinson, Jenna M. Ramaker, Tracy L. Swanson, Teri L. Wadsworth, Doris Kretzschmar, Randall L. Woltjer, Joseph F. Quinn
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 634-648 (2011)
SUMMARY A growing body of evidence supports the ‘calcium hypothesis’ of Alzheimer’s disease (AD), which postulates that a variety of insults might disrupt the homeostatic regulation of neuronal calcium (Ca2+) in the brain, resulting in the prog
Externí odkaz:
https://doaj.org/article/f3342a8f76b14e7092495bbbacfb9461
Methamphetamine (MA) is highly addictive and neurotoxic, causing cell death in humans and in rodent models. MA, along with many of its analogs, is an agonist at the G protein-coupled trace amine-associated receptor 1 (TAAR1). TAAR1 activation protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db606ac5cb00b619f8b8b6d61d0ebf7e
https://europepmc.org/articles/PMC6744391/
https://europepmc.org/articles/PMC6744391/
Autor:
Barbara A. Bricker, Uma Maheshwar Gonela, Edward Ofori, Jennifer L. Schmachtenberg, Aaron Janowsky, Tracy L. Swanson, Seth Y. Ablordeppey, Shelley H. Bloom, Amy J. Eshleman, Edem K. Onyameh, Chandrashekhar Voshavar
Publikováno v:
Eur J Med Chem
We have previously reported that dual 5-HT(1A) and 5-HT(7) receptor ligands might find utility as treatment options for various CNS related conditions including cognitive and anxiolytic impairments. We have also more recently reported that SYA16263 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cd4d2d79ea29cac08311213228c0e3
https://doi.org/10.1016/j.ejmech.2021.113243
https://doi.org/10.1016/j.ejmech.2021.113243
Autor:
Tracy L. Swanson, Sunyoung O. Kim, Katherine M. Wolfrum, Aaron Janowsky, Amy J. Eshleman, John F. Reed, Robert A. Johnson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 360:33-47
Synthetic cathinones are components of “bath salts” and have physical and psychologic side effects, including hypertension, paranoia, and hallucinations. Here, we report interactions of 20 “bath salt” components with human dopamine, serotonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9862eba441a6a5de5da06ca382b89b3e
https://doi.org/10.1124/jpet.116.236349
https://doi.org/10.1124/jpet.116.236349