Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tracy Kerby"'
Autor:
Krystal S. Bottom, David M. Ashley, Henry S. Friedman, Darryl C. Longee, Albert Moghrabi, Joanne Kurtzberg, Elizabeth Stewart, Tracy Kerby, Jennifer Lawyer, Margaret Duncan-Brown, Janis Ryan, Melody Watral, Mary Parry
Publikováno v:
Journal of Neuro-Oncology. 46:151-156
Cyclophosphamide is an alkylating agent that has shown activity in the treatment of pediatric brain tumors, including high-grade gliomas. This study was designed to evaluate the response of patients with newly diagnosed glioblastoma multiforme to pre
Autor:
Henry S. Friedman, David Graden, Peter J. Houghton, Roger E. McLendon, Janice E. Zilisch, Allan H. Friedman, Ilkcan Cokgor, Susan G. Arbuck, Tracy Kerby, Scott Fields
Publikováno v:
Cancer. 85:1160-1165
BACKGROUND Topotecan activity was evaluated for the treatment of malignant glioma. METHODS Sixty-three patients with newly diagnosed (n = 25) or recurrent (n = 38) malignant glioma were treated with topotecan at a dose of 2.6 mg/m2 over a 72-hour per
Autor:
James M. Pluda, DM Kokkinakis, Robert C. Moschel, ME Dolan, Michael M. Haglund, Henry S. Friedman, Darell D. Bigner, Jeremy N. Rich, Tracy Kerby, Allan H. Friedman, David M. Ashley, Ilkcan Cokgor, James E. Herndon, S. C. Schold, Roger E. McLendon, Anthony E. Pegg
Publikováno v:
Journal of Clinical Oncology. 16:3570-3575
PURPOSE The major mechanism of resistance to alkylnitrosourea therapy is the DNA repair protein O6-alkylguanine-DNA alkyltransferase (AGT), which removes chlorethylation or methylation damage from the O6-position of guanine. O6-benzylguanine (O6-BG)
Autor:
Tracy Kerby, Geoffrey B. Mccowage, Margaret Duncan-Brown, Herbert E. Fuchs, O. Michael Colvin, Elizabeth S. Stewart, David M. Ashley, Albert Moghrabi, Darryl C. Longee, Roger E. McLendon, Robert D. Tien, Lee Ferrell, Lisa Meier, Joanne Kurtzberg, Henry S. Friedman
Publikováno v:
Medical and Pediatric Oncology. 30:75-80
Seventeen patients less than or equal to 20 years of age with newly diagnosed (n = 10) or recurrent (n = 7) malignant gliomas (anaplastic astrocytoma and glioblastoma multiforme) were treated with cyclophosphamide in association with hematopoietic cy
Autor:
Michael L. Graham, Geoffrey B. Mccowage, Margaret Duncan-Brown, O. Michael Colvin, Joanne Kurtzberg, Roger E. McLendon, Patricia L. Robertson, Gary J. Felsberg, Albert Moghrabi, Herbert E. Fuchs, Barry Golembe, Elizabeth S. Stewart, Henry S. Friedman, Darrell D. Bigner, Robert D. Tien, Lee Ferrell, Tracy Kerby
Publikováno v:
Medical and Pediatric Oncology. 27:32-39
Leptomeningeal dissemination of childhood pilocytic astrocytoma (PA) is a rare event with little information available regarding therapy. We report here four children with disseminated PA whom we treated with high doses of cyclophosphamide with clini
Autor:
Darell D. Bigner, Michael L. Graham, David M. Ashley, Geoffrey B. Mccowage, Robert D. Tien, Lisa Meier, J. R. Casey, JM Pipas, Roger E. McLendon, Margaret Duncan-Brown, Janice F. Olson, Elizabeth S. Stewart, Linda D. Ferrell, Tracy Kerby, O M Colvin, Herbert E. Fuchs, Joanne Kurtzberg, Darryl C. Longee, Henry S. Friedman
Publikováno v:
Medical and Pediatric Oncology. 26:387-392
The outcome for patients with pineoblastoma has historically been very poor, with most patients dying of disseminated disease despite irradiation. Furthermore, the low incidence of this tumor has hindered progress toward defining better treatment str
Autor:
Henry S. Friedman, Sharon L. Smith, Tracy Kerby, Larry E. Kun, Darryl C. Longee, Fernando M. Zalduondo, Lisa Meier, Patricia K. Duffner, David M. Ashley, Amar J. Gajjar
Publikováno v:
Journal of Clinical Oncology. 14:1922-1927
PURPOSE The outcome for patients with recurrent medulloblastoma has historically been poor, with most patients dying of disseminated disease. Here, we report on seven patients with recurrent medulloblastoma, most heavily pretreated with a variety of
Autor:
Michael L. Graham, Darell D. Bigner, Beverly Hockenberger, Abbe Sue Rubin, Mark Brown, Herb Fuchs, Joanne Kurtzberg, Gary J. Felsberg, Ruth Fredericks, O. Michael Colvin, Albert Moghrabi, Margaret Duncan-Brown, Dagmar Oette, Henry S. Friedman, Daniel H. Lachance, S. Clifford Schold, Frances Ann Hayes, Barry Golembe, Elizabeth S. Stewart, Iley Browning, Robert D. Tien, Lee Ferrell, Tracy Kerby
Publikováno v:
Medical and Pediatric Oncology. 24:241-247
We conducted a dose escalation trial of cyclophosphamide plus Sargramostim in the therapy of patients with newly diagnosed or recurrent central nervous system tumors. Cyclophosphamide was administered at doses ranging between 1.0 and 2.5 g/m2 daily f
Autor:
V. Baytok, Roger J. Hudgins, Claire M. Spettell, Raymond Baule, Robin P. Humphreys, Albert Moghrabi, Paul Steinbok, D. Douglas Cochrane, Michael D. Partington, Sherman C. Stein, Robert D. Tien, Necmi Aksaray, Nora Barquin, David G. McLone, Bilgin Yüksel, Miguel Reyes-Múgica, Tadanori Tomita, Emre Alhan, Tracy Kerby, Danielle K. Boal, Şakir Altunbaşak, Pauline M. Chou, Takasumi Yasuda, Henry S. Friedman, Xiao-Di Tan, Dennis L. Johnson, William R. Boydston
Publikováno v:
Pediatric Neurosurgery. 23:I-IV
Publikováno v:
Pediatric Neurosurgery. 23:293-298
Brainstem gliomas are an important oncologic problem in the pediatric age group, constituting between 10 and 15% of childhood central nervous system neoplasms. A new classification scheme based on magnetic resonance imaging (MRI) has recently been pr