Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tracy Keates"'
Autor:
Apirat Chaikuad, Tracy Keates, Cécile Vincke, Melanie Kaufholz, Michael Zenn, Zimmermann Bastian, Carlos Gutiérrez, Rong-Guang Zhang, Catherine Hatzos-Skintges, Andrzej Joachimiak, Serge Muyldermans, Herberg, Friederich W., Knapp, S., Muller, S.
Publikováno v:
Biochemical Journal; Vol 459
Vrije Universiteit Brussel
Biochemical Journal
Vrije Universiteit Brussel
Biochemical Journal
GAK (cyclin G-associated kinase) is a key regulator of clathrin-coated vesicle trafficking and plays a central role during development. Additionally, due to the unusually high plasticity of its catalytic domain, it is a frequent ‘off-target’ of c
Autor:
Peter Canning, Christopher D.O. Cooper, Tobias Krojer, James W. Murray, Ashley C.W. Pike, Apirat Chaikuad, Tracy Keates, Chancievan Thangaratnarajah, Viktorija Hojzan, Vikram Ayinampudi, Brian D. Marsden, Opher Gileadi, Stefan Knapp, Frank von Delft, Alex N. Bullock
Publikováno v:
The Journal of Biological Chemistry
Background: BTB-Kelch proteins, including KLHL11, are proposed to bind Cul3 through a “3-box” motif to form E3 ubiquitin ligases. Results: We solved crystal structures of the KLHL11-Cul3 complex and four Kelch domains. Conclusion: The 3-box forms