Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tracy K Kambara"'
Publikováno v:
PLoS Biology, Vol 12, Iss 10, p e1001977 (2014)
Cells must coordinate DNA replication with cell division, especially during episodes of DNA damage. The paradigm for cell division control following DNA damage in bacteria involves the SOS response where cleavage of the transcriptional repressor LexA
Externí odkaz:
https://doaj.org/article/9b399878511e446dbf56b58fa65f4a77
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1543-1552 (2018)
Summary: Hfq is an RNA chaperone and an important post-transcriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions o
Externí odkaz:
https://doaj.org/article/1a2abea4d9c442e9826dcaf3e3e129c2
Publikováno v:
Proc Natl Acad Sci U S A
In the opportunistic pathogen Pseudomonas aeruginosa , RsmA is an RNA-binding protein that plays critical roles in the control of virulence, interbacterial interactions, and biofilm formation. Although RsmA is thought to exert its regulatory effects
Autor:
Simon L. Dove, Kirsty A. McFarland, Kathryn M. Ramsey, Jennifer M. Peña, Tracy K. Kambara, Samantha M. Prezioso, Padraig Deighan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In Pseudomonas aeruginosa the alp system encodes a programmed cell death pathway that is switched on in a subset of cells in response to DNA damage and is linked to the virulence of the organism. Here we show that the central regulator of this pathwa
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1543-1552 (2018)
Cell reports
Cell reports
SUMMARY Hfq is an RNA chaperone and an important posttranscriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions of
Autor:
Michele LeRoux, Kirsty A. McFarland, Tracy K. Kambara, Robin L. Kirkpatrick, Joseph D. Mougous, Emily L. Dolben, Kathryn M. Ramsey, Deborah A. Hogan, Simon L. Dove
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(27)
In mammalian cells, programmed cell death (PCD) plays important roles in development, in the removal of damaged cells, and in fighting bacterial infections. Although widespread among multicellular organisms, there are relatively few documented instan
Publikováno v:
PLoS Biology, Vol 12, Iss 10, p e1001977 (2014)
PLoS Biology
Public Library of Science
PLoS Biology
Public Library of Science
A study of the bacterium Caulobacter crescentus reveals an SOS-independent DNA damage response pathway that acts via a novel cell division inhibitor, DidA, to suppress septum synthesis.
Cells must coordinate DNA replication with cell division, e
Cells must coordinate DNA replication with cell division, e
Autor:
Jennifer M. Peña, Samantha M. Prezioso, Kirsty A. McFarland, Tracy K. Kambara, Kathryn M. Ramsey, Padraig Deighan, Simon L. Dove
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In Pseudomonas aeruginosa, the protein AlpA activates the expression of the alp locus in response to DNA damage, leading to lysis in a subset of cells and enhancing virulence of other, surviving cells. Here, the authors show that AlpA acts as an anti
Externí odkaz:
https://doaj.org/article/b438ab3975a44616a29582404e1b10c2