Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Tracy G. Anthony"'
Publikováno v:
Clocks & Sleep, Vol 5, Iss 4, Pp 639-650 (2023)
The circadian clock regulates a variety of biological processes that are normally synchronized with the solar day. Disruption of circadian rhythms is associated with health problems. Understanding the signaling mechanisms that couple cell physiology
Externí odkaz:
https://doaj.org/article/776965c8f16e4b568b2a3785d7c49928
Autor:
Wenceslao Martinez, Qian Zhang, Melissa A. Linden, Nate Schacher, Sanna Darvish, Emily T. Mirek, Jordan L. Levy, William O. Jonsson, Tracy G. Anthony, Karyn L. Hamilton
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Dietary interventions such as sulfur amino acid restriction (SAAR) target multiple drivers of aging, and show promise for preventing or delaying the onset of chronic diseases. SAAR promotes metabolic health and longevity in laboratory animals. The ef
Externí odkaz:
https://doaj.org/article/4c6709b31ba84f44ad1529f8042b1171
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The athletic horse, despite being over 50% muscle mass, remains understudied with regard to the effects of exercise and training on skeletal muscle metabolism. To begin to address this knowledge gap, we employed an untargeted metabolomics approach to
Externí odkaz:
https://doaj.org/article/fb9226b90e514950b8872c56ace6218e
Publikováno v:
Al-Qadisiyah Journal of Veterinary Medicine Sciences, Vol 16, Iss 2, Pp 162-166 (2017)
Asparaginase (ASNase) treatment results in the synthesis of some factors such as activating-transcription-factor-4 (ATF4). The eIF2-ATF4 pathway is essential for cell survival during amino acid starvation conditions. This requires the eukaryotic-init
Externí odkaz:
https://doaj.org/article/7e0a6050856546a49a2ed92e47edb8b1
Autor:
Rana J. T. Al-Baghdadi, Inna A. Nikonorova, Emily T. Mirek, Yongping Wang, Jinhee Park, William J. Belden, Ronald C. Wek, Tracy G. Anthony
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The anti-leukemic agent asparaginase activates the integrated stress response (ISR) kinase GCN2 and inhibits signaling via mechanistic target of rapamycin complex 1 (mTORC1). The study objective was to investigate the protective role of acti
Externí odkaz:
https://doaj.org/article/8c386a86451643b7ab9901fa57812237
Autor:
Alex J. Bott, Jianliang Shen, Claudia Tonelli, Le Zhan, Nithya Sivaram, Ya-Ping Jiang, Xufen Yu, Vrushank Bhatt, Eric Chiles, Hua Zhong, Sara Maimouni, Weiwei Dai, Stephani Velasquez, Ji-An Pan, Nathiya Muthalagu, Jennifer Morton, Tracy G. Anthony, Hui Feng, Wouter H. Lamers, Daniel J. Murphy, Jessie Yanxiang Guo, Jian Jin, Howard C. Crawford, Lanjing Zhang, Eileen White, Richard Z. Lin, Xiaoyang Su, David A. Tuveson, Wei-Xing Zong
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1287-1298.e6 (2019)
Summary: Glutamine is thought to play an important role in cancer cells by being deaminated via glutaminolysis to α-ketoglutarate (aKG) to fuel the tricarboxylic acid (TCA) cycle. Supporting this notion, aKG supplementation can restore growth/surviv
Externí odkaz:
https://doaj.org/article/86935149469c4359a0a906c3024b9071
Autor:
Manita Yimcharoen, Suwatsin Kittikunnathum, Chawannut Suknikorn, Wichuda Nak-on, Petcharee Yeethong, Tracy G. Anthony, Piyawan Bunpo
Publikováno v:
Journal of the International Society of Sports Nutrition, Vol 16, Iss 1 (2019)
Background Ascorbic acid is a water-soluble chain breaking antioxidant. It scavenges free radicals and reactive oxygen species (ROS), which are produced during metabolic pathways. Exercise can produce an imbalance between ROS and antioxidants, leadin
Externí odkaz:
https://doaj.org/article/a1b5a7edb950424c867d052beed2a197
Autor:
Tracy G. Anthony
Publikováno v:
Animal Nutrition, Vol 1, Iss 3, Pp 135-137 (2015)
This article provides a brief overview describing how two key signaling pathways, namely the integrated stress response and the mammalian target of rapamycin complex 1, work together to facilitate cellular adaptation to dietary amino acid insufficien
Externí odkaz:
https://doaj.org/article/4124738955ba40c19b8257685d3bd8ee
Autor:
Dorothy W. Gietzen, Tracy G. Anthony, Pierre Fafournoux, Anne-Catherine Maurin, Thomas J. Koehnle, Susan Hao
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2049-2050 (2016)
Externí odkaz:
https://doaj.org/article/a7849f98646c44c98be4156f5fc393fa
Autor:
Miriam Ferrer, Tracy G. Anthony, Janelle S. Ayres, Giulia Biffi, Justin C. Brown, Bette J. Caan, Elizabeth M. Cespedes Feliciano, Anthony P. Coll, Richard F. Dunne, Marcus D. Goncalves, Jonas Grethlein, Steven B. Heymsfield, Sheng Hui, Mariam Jamal-Hanjani, Jie Min Lam, David Y. Lewis, David McCandlish, Karen M. Mustian, Stephen O’Rahilly, Norbert Perrimon, Eileen P. White, Tobias Janowitz
Publikováno v:
Cell. 186:1824-1845