Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Tracy G Anthony"'
Publikováno v:
Journal of the International Society of Sports Nutrition, Vol 19, Iss 1, Pp 603-622 (2022)
Background Exercise modality differentially alters body composition and physical performance. Metabolic changes underlying these outcomes can be tracked through assessment of circulating metabolites. Here, global responses to an acute bout of aerobic
Externí odkaz:
https://doaj.org/article/fcc2f58994c34563928bb65ee47f595d
Autor:
Ricardo A Cordova, Jagannath Misra, Parth H Amin, Anglea J Klunk, Nur P Damayanti, Kenneth R Carlson, Andrew J Elmendorf, Hyeong-Geug Kim, Emily T Mirek, Bennet D Elzey, Marcus J Miller, X Charlie Dong, Liang Cheng, Tracy G Anthony, Roberto Pili, Ronald C Wek, Kirk A Staschke
Publikováno v:
eLife, Vol 11 (2022)
A stress adaptation pathway termed the integrated stress response has been suggested to be active in many cancers including prostate cancer (PCa). Here, we demonstrate that the eIF2 kinase GCN2 is required for sustained growth in androgen-sensitive a
Externí odkaz:
https://doaj.org/article/0e190e2bb8b949968cf1c2d48ee6413b
Autor:
Jinhee Park, Qiaoqiao Zhu, Emily Mirek, Li Na, Hamidah Raduwan, Tracy G Anthony, William J Belden
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223803 (2019)
The circadian clock and aging are intertwined. Disruption to the normal diurnal rhythm accelerates aging and corresponds with telomere shortening. Telomere attrition also correlates with increase cellular senescence and incidence of chronic disease.
Externí odkaz:
https://doaj.org/article/d040fea317564bf9a67df07bf17c18a3
Autor:
Miriam Ferrer, Tracy G. Anthony, Janelle S. Ayres, Giulia Biffi, Justin C. Brown, Bette J. Caan, Elizabeth M. Cespedes Feliciano, Anthony P. Coll, Richard F. Dunne, Marcus D. Goncalves, Jonas Grethlein, Steven B. Heymsfield, Sheng Hui, Mariam Jamal-Hanjani, Jie Min Lam, David Y. Lewis, David McCandlish, Karen M. Mustian, Stephen O’Rahilly, Norbert Perrimon, Eileen P. White, Tobias Janowitz
Publikováno v:
Cell. 186:1824-1845
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The athletic horse, despite being over 50% muscle mass, remains understudied with regard to the effects of exercise and training on skeletal muscle metabolism. To begin to address this knowledge gap, we employed an untargeted metabolomics approach to
Externí odkaz:
https://doaj.org/article/fb9226b90e514950b8872c56ace6218e
Publikováno v:
Al-Qadisiyah Journal of Veterinary Medicine Sciences, Vol 16, Iss 2, Pp 162-166 (2017)
Asparaginase (ASNase) treatment results in the synthesis of some factors such as activating-transcription-factor-4 (ATF4). The eIF2-ATF4 pathway is essential for cell survival during amino acid starvation conditions. This requires the eukaryotic-init
Externí odkaz:
https://doaj.org/article/7e0a6050856546a49a2ed92e47edb8b1
Autor:
Alex J. Bott, Jianliang Shen, Claudia Tonelli, Le Zhan, Nithya Sivaram, Ya-Ping Jiang, Xufen Yu, Vrushank Bhatt, Eric Chiles, Hua Zhong, Sara Maimouni, Weiwei Dai, Stephani Velasquez, Ji-An Pan, Nathiya Muthalagu, Jennifer Morton, Tracy G. Anthony, Hui Feng, Wouter H. Lamers, Daniel J. Murphy, Jessie Yanxiang Guo, Jian Jin, Howard C. Crawford, Lanjing Zhang, Eileen White, Richard Z. Lin, Xiaoyang Su, David A. Tuveson, Wei-Xing Zong
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1287-1298.e6 (2019)
Summary: Glutamine is thought to play an important role in cancer cells by being deaminated via glutaminolysis to α-ketoglutarate (aKG) to fuel the tricarboxylic acid (TCA) cycle. Supporting this notion, aKG supplementation can restore growth/surviv
Externí odkaz:
https://doaj.org/article/86935149469c4359a0a906c3024b9071
Publikováno v:
Antioxidants & Redox Signaling.
Autor:
William O. Jonsson, Agnieszka K. Borowik, Atul Pranay, Michael T. Kinter, Emily T. Mirek, Jordan L. Levy, Elizabeth M. Snyder, Benjamin F. Miller, Tracy G. Anthony
Publikováno v:
GeroScience.
Dietary sulfur amino acid restriction (SAAR) protects against diet-induced obesity, extends healthspan, and coincides with an overall reduction in hepatic protein synthesis. To explore the underpinnings of SAAR-induced slowed growth and its impact on
Autor:
Cheng-Yu Tsai, Toshie Saito, Mayur Sarangdhar, Maisam Abu-El-Haija, Li Wen, Bomi Lee, Mang Yu, Den A. Lipata, Murli Manohar, Monique T. Barakat, Kévin Contrepois, Thai Hoa Tran, Yves Theoret, Na Bo, Ying Ding, Kristen Stevenson, Elena J. Ladas, Lewis B. Silverman, Loredana Quadro, Tracy G. Anthony, Anil G. Jegga, Sohail Z. Husain
Publikováno v:
Sci Transl Med
Among drug-induced adverse events, pancreatitis is life-threatening and results in substantial morbidity. A prototype example is the pancreatitis caused by asparaginase, a crucial drug used to treat acute lymphoblastic leukemia (ALL). Here, we used a