Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Tracy Curley"'
Autor:
Wassim Abida, Daniel Vargas Pivato de Almeida, Erica Simone Dayan, Raymond E. Baser, Daniel C. Danila, Tracy Curley, Justine Anderson, Howard I. Scher, Gabrielle Arauz, Susan F. Slovin, Michael J. Morris, Karen A. Autio
Publikováno v:
Journal of Clinical Oncology. 38:e24174-e24174
e24174 Background: Incorporation of the PRO-CTCAE during chemotherapy is associated with fewer ER visits and improved survival. Limited data exist using this tool to capture irAE in immunotherapy trials. We collected select PRO-CTCAEs in a clinical t
Autor:
Yu Chen, Alba Torres, Kalyan Banda, Andrew C. Hsieh, Dana E. Rathkopf, Brett S. Carver, Tamara L. Lotan, Tracy Curley, Greg Shelkey, Howard I. Scher, Laura S Graham, Katie Pisano
BACKGROUND: MLN0128 is a first-in-class, dual mTOR inhibitor with potential to outperform standard rapalogs through inhibition of TORC1 and TORC2. This phase II study was designed to assess antitumor activity of MLN0128 in metastatic castration-resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292efdbefe396372502e97216e2ee947
https://europepmc.org/articles/PMC6050986/
https://europepmc.org/articles/PMC6050986/
Autor:
Lawrence H. Schwartz, Tracy Curley, Dana E. Rathkopf, Chaitanya R. Divgi, Xiaoyu Jia, Christina Hong, Neeta Pandit-Taskar, Anthony Delacruz, Joseph A. O'Donoghue, Steven M. Larson, David B. Solit, William Kevin Kelly, Gretchen Gignac, Ryan D. Stephenson, Howard I. Scher, Glenn Heller, Susan F. Slovin, Michael J. Morris, Jorge A. Carrasquillo
Publikováno v:
Journal of Clinical Oncology. 27:2436-2442
Purpose Early studies of patients with castration-resistant metastatic prostate cancer (CRMPC) suggest that chemotherapy administered with a dose of a bone-seeking radiopharmaceutical is superior to chemotherapy alone. To build on this strategy and f
Autor:
Connie Collins, Glenn Heller, Michael A. Carducci, Samuel R. Denmeade, Martin Fleisher, Roberto Pili, Dana E. Rathkopf, Mario A. Eisenberger, Tracy Curley, Moshe A. Kelsen, Howard I. Scher, Susan F. Slovin, Michael J. Morris, Sharyn D. Baker, Melinda Halter
Publikováno v:
Journal of Clinical Oncology. 26:2959-2965
Purpose We evaluated rapid androgen cycling in combination with docetaxel for men with progressive noncastrate prostate cancers. Patients and Methods Noncastrate patients with ≤ 6 months of hormone therapy were eligible. Cohort 1 (62 patients) rece
Publikováno v:
Clinical journal of oncology nursing. 19(2)
Background Radium-223 dichloride, or radium-223, is a first-in-class alpha emitter that selectively targets bone metastases with high-energy, short-range alpha particles and is approved for the treatment of patients with castration-resistant prostate
Autor:
Lawrence H. Schwartz, Lee M. Krug, W. Kevin Kelly, Paul A. Marks, Judy H. Chiao, Stacie Richardson, Tracy Curley
Publikováno v:
Clinical Lung Cancer. 7:257-261
Background Histone deacetylase inhibitors are a novel class of therapeutic agents that inhibit deacetylate histones and other proteins involved in the regulation of gene expression and cell cycle progression. Phase I trials of intravenous and oral fo
Autor:
Neeta Pandit-Taskar, Susan F. Slovin, Michael J. Morris, Joseph A. O'Donoghue, Jennifer Halpern, Tracy Curley, Peter Smith-Jones, Angelo Nacca, Anthony Delacruz, Ronald D. Finn, Lawrence H. Schwartz, Nyasha Warren, Steven M. Larson, W. Kevin Kelly, Maria Batraki, Chaitanya R. Divgi, Philip O. Livingston, Howard I. Scher, David B. Solit
Publikováno v:
Clinical Cancer Research. 11:7454-7461
Background: Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein primarily expressed on benign and malignant prostatic epithelial cells. J591 is an IgG1 monoclonal antibody that targets the external domain of the PSMA. The relati
Autor:
Lawrence H. Schwartz, Barbara MacGregore-Cortelli, Lee M. Krug, Howard I. Scher, Stacy Richardson, Mark L. Heaney, Semra Olgac, Tracy Curley, Elaina Chu, Victoria M. Richon, J. Paul Secrist, William P. Tong, Owen A. O'Connor, Judy H. Chiao, Paul A. Marks, William Kevin Kelly
Publikováno v:
Journal of Clinical Oncology. 23:3923-3931
Purpose To determine the safety, dosing schedules, pharmacokinetic profile, and biologic effect of orally administered histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) in patients with advanced cancer. Patients and Methods Patient
Autor:
Tracy Curley, Louis Martone, W. Kevin Kelly, David Smith, Eric J. Small, Isan Chen, A. Dimitrios Colevas, Anthony Delacruz, William Oh, Matthew D. Galsky, Howard I. Scher
Publikováno v:
Journal of Clinical Oncology. 23:1439-1446
Purpose To evaluate the antitumor activity and safety of the epothilone B analog, ixabepilone, with or without estramustine phosphate (EMP), in chemotherapy-naive patients with progressive castrate metastatic prostate cancer. Patients and Methods Pat
Autor:
Tracy Curley, Howard I. Scher, Daniel C. Danila, Anuradha Gopalan, Erica Simone Dayan, James A. Eastham, Peter T. Scardino, Lawrence P. Bellomo, Phillip Wong, Vincent P. Laudone, Susan F. Slovin, Michael J. Morris, Wassim Abida, Karen A. Autio, Karim Touijer
Publikováno v:
Journal of Clinical Oncology. 35:203-203
203 Background: Androgen deprivation therapy (ADT) does not completely eliminate disease in mNCPC or BRPC. We explored a multimodality treatment (tx) approach combining ADT with ipilimumab (ipi) with the aim of achieving no evidence of disease or com