Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tracy A. Hookway"'
Autor:
Doan C. Nguyen, Tracy A. Hookway, Qingling Wu, Rajneesh Jha, Marcela K. Preininger, Xuemin Chen, Charles A. Easley, Paul Spearman, Shriprasad R. Deshpande, Kevin Maher, Mary B. Wagner, Todd C. McDevitt, Chunhui Xu
Publikováno v:
Stem Cell Reports, Vol 3, Iss 2, Pp 260-268 (2014)
Cardiomyocytes derived from human pluripotent stem cells (hPSCs) are a promising cell source for regenerative medicine, disease modeling, and drug discovery, all of which require enriched cardiomyocytes, ideally ones with mature phenotypes. However,
Externí odkaz:
https://doaj.org/article/288fb5c67c3d43f3a51cb2e567c4f074
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 143:105880
Autor:
David A Joy, Tracy A. Hookway, Oriane B. Matthys, Todd C. McDevitt, Reuben Thomas, Jessica E. Sepulveda
Technological advancements have enabled the design of increasingly complex engineered tissue constructs, which better mimic native tissue cellularity. Therefore, dissecting the bi-directional interactions between distinct cell types in 3D is necessar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8baed1ec0b45a564cfa2fc3a3417d174
https://doi.org/10.1101/2020.07.06.190504
https://doi.org/10.1101/2020.07.06.190504
Single-Cell Determination of Cardiac Microtissue Structure and Function Using Light Sheet Microscopy
Autor:
David A Joy, Meredith E. K. Calvert, Diwakar Turaga, Todd C. McDevitt, Tracy A. Hookway, Oriane B. Matthys
Publikováno v:
Tissue engineering. Part C, Methods. 26(4)
Native cardiac tissue is composed of heterogeneous cell populations that work cooperatively for proper tissue function; thus, engineered tissue models have moved toward incorporating multiple cardiac cell types in an effort to recapitulate native mul
Single cell determination of cardiac microtissue structure and function using light sheet microscopy
Autor:
Todd C. McDevitt, David A Joy, Meredith E. K. Calvert, Diwakar Turaga, Tracy A. Hookway, Oriane B. Matthys
Native cardiac tissue is comprised of heterogeneous cell populations that work cooperatively for proper tissue function; thus, engineered tissue models have moved toward incorporating multiple cardiac cell types in an effort to recapitulate native mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0466187497ab9e8b1d4f5fcfd2db6042
https://doi.org/10.1101/2020.01.22.915926
https://doi.org/10.1101/2020.01.22.915926
Autor:
Tracy A. Hookway
Publikováno v:
Trends in Biotechnology. 36:341-343
Achieving complex self-organization in vitro has remained a fundamental challenge in tissue engineering. A recent study in Developmental Cell by Hughes and colleagues uses computational and experimental approaches to understand and control the morpho
Phenotypic Variation Between Stromal Cells Differentially Impacts Engineered Cardiac Tissue Function
Autor:
David A Joy, Jessica E. Sepulveda, Tracy A. Hookway, Oriane B. Matthys, Sarah Rains, Federico N Mendoza-Camacho, Todd C. McDevitt
Publikováno v:
Tissue Eng Part A
Tissue engineering. Part A, vol 25, iss 9-10
Tissue engineering. Part A, vol 25, iss 9-10
Throughout heart development, cardiomyocytes differentiate and mature in direct contact with nonparenchymal cell types, such as cardiac fibroblasts. Thus, when modeling myocardial tissue in vitro, tissue engineers include a supporting stromal cell po
Publikováno v:
Journal of Visualized Experiments : JoVE
Engineered tissues are being used clinically for tissue repair and replacement, and are being developed as tools for drug screening and human disease modeling. Self-assembled tissues offer advantages over scaffold-based tissue engineering, such as en
Autor:
Gianfranco Beniamino Fiore, Eben Alsberg, Tracy A. Hookway, Marco Piola, Monica Soncini, Hannah A. Strobel, Marsha W. Rolle
Tissue-engineered human blood vessels may enable in vitro disease modeling and drug screening to accelerate advances in vascular medicine. Existing methods for tissue-engineered blood vessel (TEBV) fabrication create homogenous tubes not conducive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1868e52936af002d102d367ceec346e7
http://hdl.handle.net/11311/1079601
http://hdl.handle.net/11311/1079601
Autor:
Praveen Taneja, Frederico N. Mendoza-Camacho, Linda J. Noble-Haeusslein, Casey A. Gifford, Jorge Alexis Martinez-Vargas, Jessica C. Butts, Tracy A. Hookway, Todd C. McDevitt, Dylan A. McCreedy
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 19
The spinal cord consists of multiple neuronal cell types that are critical to motor control and arise from distinct progenitor domains in the developing neural tube. Excitatory V2a interneurons in particular are an integral component of central patte