Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tracy A. Cole"'
Autor:
Tracy A. Cole, Hien Zhao, Timothy J. Collier, Ivette Sandoval, Caryl E. Sortwell, Kathy Steece-Collier, Brian F. Daley, Alix Booms, Jack Lipton, Mackenzie Welch, Melissa Berman, Luke Jandreski, Danielle Graham, Andreas Weihofen, Stephanie Celano, Emily Schulz, Allyson Cole-Strauss, Esteban Luna, Duc Quach, Apoorva Mohan, C. Frank Bennett, Eric E. Swayze, Holly B. Kordasiewicz, Kelvin C. Luk, Katrina L. Paumier
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Parkinson’s disease (PD) is a prevalent neurodegenerative disease with no approved disease-modifying therapies. Multiplications, mutations, and single nucleotide polymorphisms in the SNCA gene, encoding α-synuclein (aSyn) protein, either cause or
Externí odkaz:
https://doaj.org/article/d06ea6f3c76f4b97a20be199ac938389
Autor:
Michael X. Hernandez, Shan Jiang, Tracy A. Cole, Shu-Hui Chu, Maria I. Fonseca, Melody J. Fang, Lindsay A. Hohsfield, Maria D. Torres, Kim N. Green, Rick A. Wetsel, Ali Mortazavi, Andrea J. Tenner
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2017)
Abstract Background Pharmacologic inhibition of C5aR1, a receptor for the complement activation proinflammatory fragment, C5a, suppressed pathology and cognitive deficits in Alzheimer's disease (AD) mouse models. To validate that the effect of the an
Externí odkaz:
https://doaj.org/article/8eb524f09fa344599b227977638d4d31
Autor:
Tracy A Cole, Xia Yang, Graciel Diamante, Jie Gao, Xu Xiao, Peter Tontonoz, Russell Littman, In Sook Ahn
Publikováno v:
Molecular and cellular biology, vol 40, iss 8
Mol Cell Biol
Mol Cell Biol
Brain lipoprotein receptors have been shown to regulate the metabolism of ApoE and β-amyloid (Aβ) and are potential therapeutic targets for Alzheimer’s disease (AD). Previously, we identified E3 ubiquitin ligase IDOL as a negative regulator of br
Autor:
Jie Gao, Stephen Lee, Jason K. Kim, Daniel Lindén, In Sook Ahn, Tracy A Cole, Andrea Ahnmark, Xia Yang, Magnus Althage, Stephanie M. Correa, Frank Seeliger, Harriet Andersén, Helen Boyd, Pernilla Eliasson, Peter Tontonoz, Ingela Maxvall, J. Edward van Veen, Alba Carreras, Anna C. Calkin, Cynthia Hong, Mohammad Bohlooly-Y, Mikael Bjursell, Peter Åkerblad, Megan G. Massa, Christina Priest, Michelle J. Porritt, Graciel Diamante, Richard T. Lee, Prashant Rajbhandari, Douglas Arneson
Publikováno v:
Nature metabolism, vol 1, iss 11
Nature metabolism
Nature metabolism
Liver X receptors limit cellular lipid uptake by stimulating the transcription of Inducible Degrader of the LDL Receptor (IDOL), an E3 ubiquitin ligase that targets lipoprotein receptors for degradation. The function of IDOL in systemic metabolism is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92483fa48677032510e1ff08d752b28d
https://escholarship.org/uc/item/8xp778j5
https://escholarship.org/uc/item/8xp778j5
Autor:
Lindsay A. Hohsfield, Michael X. Hernandez, Maria D. Torres, Melody J. Fang, Shan Jiang, Maria I. Fonseca, Shu Hui Chu, Kim N. Green, Ali Mortazavi, Rick A. Wetsel, Tracy A. Cole, Andrea J. Tenner
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2017)
Hernandez, MX; Jiang, S; Cole, TA; Chu, S-H; Fonseca, MI; Fang, MJ; et al.(2017). Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. MOLECULAR NEURODEGENERATION, 12. doi: 10.1186/s13024-017-0210-z. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/72n4f4fj
Molecular Neurodegeneration
Hernandez, MX; Jiang, S; Cole, TA; Chu, S-H; Fonseca, MI; Fang, MJ; et al.(2017). Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. MOLECULAR NEURODEGENERATION, 12. doi: 10.1186/s13024-017-0210-z. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/72n4f4fj
Molecular Neurodegeneration
Background Pharmacologic inhibition of C5aR1, a receptor for the complement activation proinflammatory fragment, C5a, suppressed pathology and cognitive deficits in Alzheimer's disease (AD) mouse models. To validate that the effect of the antagonist
Autor:
Tracy L. Cole, Tara P. Dasgupta, Colin D. Hubbard, Paul H. Miyares, Suzanne Leebert, John Burgess
Publikováno v:
Transition Metal Chemistry. 30:957-963
The kinetics of base hydrolysis of the low-spin iron(II)-diimine complex [Fe(fertri)3]2+, where fertri=3-(2-pyridyl)-5,6-bis(2-furyl)-1,2,4-triazine, as a function of hydroxide concentration, solvent composition (water; aqueous MeOH), and pressure ar
Publikováno v:
International Journal for the Scholarship of Teaching and Learning, Vol 6, Iss 2 (2012)
What are the most efficient and effective methods in measuring outcomes for assurance of learning in higher education? This study examines the merits of outsourcing part of the assessment workload by comparing ratings completed by trained student int
Publikováno v:
Molecular Immunology. 47:2274-2274
Autor:
John Burgess, Colin D. Hubbard, Paul H. Miyares, Tracy L. Cole, Tara P. Dasgupta, Suzanne Leebert
Publikováno v:
Transition Metal Chemistry; Nov2005, Vol. 30 Issue 8, p957-963, 7p
Publikováno v:
Weed Science. 37:639-644
Imazethapyr was applied at 0.14 kg ae/ha to soybean, peanut, sicklepod. Florida beggarweed, and redroot pigweed as either a soil, foliar, or soil plus foliar application. Soybean and peanut were the most tolerant species; redroot pigweed was the most