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pro vyhledávání: '"Tracy A. Chin"'
Publikováno v:
Cell Motility and the Cytoskeleton. 33:208-222
Several metal ions are known to cause depolymerization of the actin cytoskeleton under some circumstances. We found that in renal mesangial and vascular smooth muscle cells, micromolar concentrations of Cd2+ result in loss of phalloidinstainable fila
Autor:
Douglas M. Templeton, Tracy A. Chin
Publikováno v:
Toxicology. 77:145-156
Exposure of cultured rat mesangial cells to CdCl2 caused a dose- and time-dependent increase in intracellular glutathione that was significant at 0.5 microM and maximal at 1 microM Cd2+. The effect depended on glutathione synthesis and was masked by
Publikováno v:
Carcinogenesis. 12:29-34
We have determined the mutational specificity of the 5-nitrofuran derivative furylfuramide (AF2) in the lacI gene of Escherichia coli. Treatment of a delta uvrB, pKM101 strain with 1 M AF2 yielded a mutation frequency approximately 300 times greater
Autor:
Tracy A. Chin, Douglas M. Templeton
Publikováno v:
Toxicology and applied pharmacology. 116(1)
Cadmium is a potent nephrotoxin known to cause damage to the proximal tubular epithelium in vivo. The renal glomerulus is less frequently a target and is sensitive to Cd in vitro. We have previously presented evidence that the mesangial cell is a maj